Robert (Bob) Blouin, Pharm.D., is the Bryson Distinguished Professor in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC Eshelman School of Pharmacy. Dr. Blouin’s academic interests are in the areas of pharmacokinetics, drug metabolism, and the effect of disease and altered physiologic states on the disposition of drugs.
Drug Optimization: PhD Program
Working from bench to bedside
The Division of Pharmacotherapy and Experimental Therapeutics has the unique responsibility within the UNC Eshelman School of Pharmacy to provide classroom and clinical instruction for pharmacy students in the practice of pharmacy and to train graduate and postgraduate scientists in the principles of translational research. We engage in innovative teaching and research, preparing our students to be professional and scientific leaders.
Our PhD program develops scientists who excel at conducting innovative and clinically relevant translational research that integrates biomedical and pharmaceutical sciences in a laboratory- and computer-based environments that leverage preclinical and clinical investigations.
We generate and disseminate new knowledge in pharmacotherapy and accelerate its application to improve patient care through:
- Delivering innovative education and training
- Integrating experimental and clinical pharmacology discoveries into the practice of precision medicine
- Unique collaborations with industry, regulatory agencies, renowned health science centers, and international entities
- Leading and participating in local, state, national and international organizations, communities, and programs.
- Engaging students in innovative clinical and translational research
Tracks for Clinicians and Non-Clinicians
The concentration area in pharmacotherapy and experimental therapeutics was developed with two curricular tracks based on previous experience of the applicant:
- Clinician track: for students with a Pharm.D. or M.D., or equivalent
- Nonclinician track: for highly motivated, exceptionally qualified students lacking previous clinical training
Areas of coursework and research
- Drug metabolism and transport
- Pharmacokinetics/pharmacodynamics/pharmacometrics
- Pharmacogenomics/genomics
- Clinical research
- Experimental therapeutics
- Mechanisms of drug toxicity
These are applied to therapeutic areas, including:
- cardiovascular disease,
- epilepsy/neurological diseases,
- hepatology/gastroenterology/transplant,
- infectious disease/HIV,
- oncology/hematology, and
- pulmonary disease
Graduates from both tracks have enjoyed an outstanding employment rate in both academia and the pharmaceutical industry.
DPET Fellowship and Graduate Student 2022 Recorded Webinar & Brochure
Information specific to the graduate program begins at 01:02 in the webinar video.
2022 Webinar BrochureCurriculum
Faculty and Staff
Our faculty include clinical practitioners who bring insights from the patient-care setting to their teaching, translational research, and professional service activities. Many of our faculty hold joint appointments in the UNC School of Medicine, the Department of Pharmacy at the UNC Medical Center, and other allied health schools. They lend their expertise through speaking engagements and memberships on advisory panels and committees, and play important roles in local, state, national, and international organizations.
DPET Faculty
Kim L. R. Brouwer
Kim L.R. Brouwer, Pharm.D., Ph.D., is the William R. Kenan Jr. Distinguished Professor in the Division of Pharmacotherapy and Experimental Therapeutics of the UNC Eshelman School of Pharmacy, associate dean for research and graduate education, and a professor in the curriculum in toxicology.
Yanguang Cao
Yanguang Cao, Ph.D., joined the UNC Eshelman School of Pharmacy initially as an assistant professor and then promoted as an associate professor in the division of Pharmacotherapy and Experimental Therapeutics. Prior to joining the School, Cao served as a research assistant professor at SUNY Buffalo for two years after completing a postdoctoral training program at SUNY, Buffalo.
Rachel Church
Rachel Church, PhD, is an assistant professor within the Division of Pharmacotherapy and Experimental Therapeutics and the Director of the Organ Injury Biomarker Core within the UNC Institute for Drug Safety Sciences. Dr. Church has expertise in identifying and characterizing novel translational biomarkers of drug-induced organ injury, especially drug-induced liver injury, and developing innovative methodologies to maximize the utility of traditional biomarkers.
Amber Cipriani
Amber.Cipriani@unchealth.unc.edu
Amber Cipriani, Pharm.D., joined the UNC Eshelman School of Pharmacy as a clinical assistant professor in the Division of Pharmacotherapy and Experimental Therapy. Cipriani’s appointment is cofunded by UNC Hospitals, where she serves as a clinical oncology specialist in thoracic oncology.
Amanda Corbett
Amanda Corbett, Pharm.D., is an associate professor in the Division of Pharmacotherapy and Experimental Therapeutics and the Global Pharmacology Coordinator for the UNC Institute of Global Health and Infectious Diseases. Her expertise are in HIV, antiviral, and opportunistic infection clinical pharmacy and ethnopharmacology. She has extensive experience in developing countries and more recently in integrative medicine practices.
Mackenzie Leigh Cottrell
Mackenzie Cottrell, Pharm.D., M.S. is an assistant professor in the Division of Pharmacotherapy and Experimental Therapeutics. Her research focuses on describing pharmacokinetic/pharmacodynamic relationships in mucosal tissues for antiretrovirals being used in HIV prevention and cure interventions.
Daniel Crona
Daniel Crona, Pharm.D., Ph.D., joined the UNC Eshelman School of Pharmacy in 2015. His translational research program focuses on how genetic variations can lead to differences in the pharmacokinetics and pharmacodynamics of therapeutic treatments used in oncology, and how inter-individual differences in clinical pharmacology measures can affect survival and drug toxicity phenotypes.
Julie Dumond
Julie Dumond, Pharm.D., M.S., is an associate professor in the Division of Pharmacotherapy and Experimental Therapeutics. Her primary research interest is the pharmacokinetics/pharmacodynamics of antiretrovirals. She is currently conducting a clinical study in aging, HIV-infected subjects to explore the effects of cellular aging and frailty on antiretroviral toxicity and efficacy.
Robert Dupuis
Robert Dupuis, PharmD, FCCO, is a clinical professor and vice department chair within the Division of Pharmacotherapy and Experimental Therapeutics. Dr. Dupuis is also the division’s director of fellowship programs. In this role, he advises postdoctoral fellows on clinical research in the areas of regulatory affairs, medical affairs, clinical development, and pharmacometrics. Dr. Dupuis has expertise in clinical pharmacology, drug metabolism, drug disposition, pharmacogenomics, adverse effects, outcomes and enhancement of care.
Amber Frick
Amber Frick, Pharm.D., Ph.D., is an assistant professor with the Division of Pharmacotherapy and Experimental Therapeutics. Her main responsibilities at the School are to develop an expertise in the implementation and assessment of new approaches to and best practices in teaching while also taking part in collaborative teaching activities.
Daniel Gonzalez
Daniel Gonzalez, Pharm.D., Ph.D., is an associate professor in the Division of Pharmacotherapy and Experimental Therapeutics. His research interests include pediatric clinical pharmacology and the application of mathematical modeling and simulation techniques to characterize the pharmacokinetics and pharmacodynamics of drugs, guide dosage selection, and improve drug safety in children.
Erin Heinzen
The Heinzen Lab focuses on the genetic and genomic basis of epilepsy disorders, including analyses of the role of germline mutations, somatic mutations, and how regulation of the cellular transcriptome influences the risk and presentation of seizures. In collaboration with a number of investigators in neurology, neuropathology, and neurosurgery, my group is to studies the role of somatic mutations in epilepsy and other neurological diseases.
Klarissa Dawniette Jackson
Klarissa Jackson joined the faculty at the UNC Eshelman School of Pharmacy as an assistant professor in the Division of Pharmacotherapy and Experimental Therapeutics. Jackson obtained her B.S. in chemistry from Jackson State University and her Ph.D. in pharmacology from Vanderbilt University. She completed a postdoctoral fellowship at the University of Washington School of Pharmacy in the Department of Medicinal Chemistry under the mentorship of Drs. Allan Rettie and Sidney Nelson. Prior to joining the faculty at UNC, Jackson was as an assistant professor at Lipscomb University College of Pharmacy in the Department of Pharmaceutical Sciences and an adjunct assistant professor in the Department of Pharmacology at Vanderbilt University.
Angela Kashuba
Dr. Kashuba’s research focuses on the clinical pharmacology of drugs used in the treatment, prevention, and cure of HIV infection. She is working on optimizing dosing strategies for HIV prevention including the role of sex and ethnicity, characterizing drug distribution in putative viral reservoirs using mass spectrometry imaging, determining predictors of drug tissue distribution, and developing in vitro models for optimizing combination therapy for HIV cure.
Dulcie Lai, Pharm.D., Ph.D.
Dr. Lai is a research assistant professor in the Heinzen Lab. She focuses on modeling SLC35A2 epilepsy in hiPSC-derived neuronal models.
Craig Lee
RECRUITING GRADUATE STUDENTS
Craig Lee, Pharm.D, Ph.D. is a professor and the chair of the Division of Pharmacotherapy and Experimental Therapeutics. His research focuses on cytochrome P450 metabolism, cardiovascular experimental therapeutics, and precision medicine/pharmacogenomics.
Benyam Muluneh
Benyam Muluneh, Pharm.D., is an assistant professor in the Division of Pharmacotherapy and Experimental Therapeutics. Muluneh coordinates a course in the integrative pharmacotherapy series and teaches in several PharmD courses. His research interests include optimization of pharmacotherapy in leukemias through the precision dosing initiative and a multidimensional approach to understanding and improving adherence to oral oncolytics. Muluneh also leads the school’s collaborations with Addis Ababa University in Ethiopia with a focus on hematology/oncology including serving as a GPS preceptor.
Herb Patterson
Herb Patterson, Pharm.D., is a professor in the Division of Pharmacotherapy and Experimental Therapeutics and a research professor of medicine at the University of North Carolina at Chapel Hill. His clinical research focuses on drugs used in heart failure.
Adam M Persky
Adam Persky is a professor in the Division of Pharmacotherapy and Experimental Therapeutics. He teaches physiology and pharmacokinetics. His research focuses on translating the science of learning and memory into practical application in the classroom and experiential settings.
Gauri Rao
Gauri Rao, Pharm.D., M.S., is an associate professor in the Division of Pharmacotherapy and Experimental Therapeutics. Rao’s principal research interests surround quantitative systems pharmacology, and she is working to understand the processes of infectious diseases.
Jo Ellen Rodgers
Jo Ellen Rodgers, Pharm.D., is a professor in the Division of Pharmacotherapy and Experimental Therapeutics and serves as director of postdoctoral programs for the Eshelman School of Pharmacy. Rodgers’ primary research interest is in the care of heart failure patients.
Elias Rosen
Dr. Rosen’s research focuses on the development of methods to measure intracellular distribution of therapeutics and their metabolites in a variety of biological matrices using mass spectrometry imaging. He is currently quantifying the penetration of drugs relevant to HIV treatment and eradication into putative viral reservoirs, and combining this approach with traditional imaging modalities to evaluate efficacy of experimental treatment regimens.
Deborah Sturpe
Deborah Sturpe, PharmD, MA, BCPS is a clinical associate professor in the Division of Pharmacotherapy and Experimental Therapeutics. Her primary responsibilities in the Eshelman School of Pharmacy include didactic teaching, ambulatory care practice, and investigating how to best teach and assess students. In particular, she is interested in PharmD curricular revision and curricular/program assessment planning as well as best practices in competency education and performance-based assessment. Dr. Sturpe also serves as Associate Editor for Manuscript Quality for the journal Currents in Pharmacy Teaching and Learning.
Jacqueline B. Tiley
Jacqueline B. Tiley, Ph.D., is an assistant professor in the Division of Pharmacotherapy and Experimental Therapeutics. Her research interest is on disease- and drug-mediated alterations in hepatic and placental transport proteins and its impact on drug disposition and toxicity. Her overall goal is to improve the safety of medications used during pregnancy and breastfeeding, as well as advance precision medicine strategies.
Michael Wagner
Paul B. Watkins
Paul Watkins, M.D., is director of the the Watkins Lab for Drug Safety Sciences at the UNC Eshelman School of Pharmacy and the Howard Q. Ferguson Distinguished Professor in the Division of Pharmacotherapy and Experimental Therapeutics.
Dennis Williams
Dennis Williams, Pharm.D., is an associate professor and the vice chair for professional education and practice for the Division of Pharmacotherapy and Experimental Therapeutics.
Tim Wiltshire
Tim Wiltshire, Ph.D., is an associate professor in the Division of Pharmacotherapy and Experimental Therapeutics and Director of the UNC Center for Pharmacogenomics and Individualized Therapy. The major focus of his laboratory and CPIT is to take the pharmacogenetic knowledge we already have and develop approaches for that information to be used effectively in clinical practice.
William Zamboni
William Zamboni, Pharm.D., Ph.D., is a professor in the Division of Pharmacotherapy and Experimental Therapeutics and UNC Lineberger Comprehensive Cancer Center. He is the director of the UNC Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Lab and Recharge Center in the Eshelman School of Pharmacy, the UNC Lineberger Comprehensive Cancer Center (LCCC), and the Carolina Institute of Nanomedicine. His research interests focus on the application of pharmacokinetic, pharmacodynamic, and pharmacogenetic principles in the optimization of the chemotherapeutic treatment of cancer.
DPET Joint Appointments
DPET Adjunct Faculty
Kirkwood Adams, MD
Adams is an associate professor of medicine and radiology at the University of North Carolina. He specializes in heart failure, nuclear cardiology, cardiac transplantation, and general cardiology.
Hugh A. Barton, PhD
Barton currently works as a consultant for Barton Systems Pharmacology and Toxicology. His area of expertise includes translational modeling and stimulation, pharmacokinetics, and dynamics and metabolism.
Danny Benjamin, MD, PhD, MPH, Kiser-Arena Distinguished Professor of Pediatrics
Benjamin’s research group pioneered much of the methods in completing pharmacokinetic and safety trials in premature infants. His group has since expanded to the study of therapeutics in children of all ages and most therapeutic areas as evidenced by >300 publications in peer-reviewed journals.
William Brock, PhD
Brock has expertise and experience with non-clinical safety program study design, conduct, interpretation and reporting for a broad range of xenobiotics.
Gilbert Burckart, PharmD
Burkhart is the associate director of pediatrics in the office of clinical pharmacology at the US Food and Drug Administration.
Scott Clark, PhD
Clark, of SCSClark Networks, specializes in pharmacogenomics.
Michael Cohen-Wolkowiez, MD, PhD
Cohen-Wolkowiez is a professor of Pediatrics at Duke University. His areas of expertise include minimal-risk methods including bioanalytical, PK/PD modeling, and clinical trial design to advance pediatric drug development.
Austin Combest, PharmD, BCOP, MBA
Combest is the senior director of Clinical Science and Information for PPD’s Strategic Development Consulting group and head of the clinical science department at PPD. His therapeutic area of expertise is in hematology/oncology, with a strong background in immune-oncology, pharmacokinetics and pharmacology, pharmaceutics, nanoparticles, biologics, biosimilars, epidemiology, and pharmacogenomics. He has experience with all phases of drug development from preclinical to Phase IV.
Ronald Fleming, PharmD
Fleming’s research area is oncology and provides expertise in the pharmaceutical industry.
John Edgar French, PhD
French is involved in research collaborations with DPET in the area of toxicology, genetics, and nutrient impact on experimental therapies for cancer.
Giulia Ghibellini, PhD
Ghibellini is a director of clinical pharmacology at Teva Pharmaceuticals (Specialty Products) and the team leader for the Clinical Pharmacology group in the US. Her research expertise is in the fields of pharmacokinetics and clinical pharmacology.
Roberto Gomeni, PhD, HDR
Gomeni is the former global head of pharmacometrics for GlaxoSmithKline. His experience includes the development of novel pharmacometrics methodologies for improving efficiency of placebo-controlled clinical trials of antidepressant drugs, analyzing data of clinical trials, and for developing a disease progression model for amyotrophic lateral sclerosis.
Alison H. Harrill, PhD
Harrill is a geneticist at the National Toxicology Program (NIH/NIEHS). Her area of research covers systems toxicology, pharmacogenetics and personalized medicine, and biomarkers.
Alan Higgins, PhD
Higgins, of Baskerville Consulting, is an expert in the field of preclinical drug development.
Howard L. McLeod, PharmD
McLeod’s research is focused on pharmacogenomics and individualized therapy. He is affiliated with Moffitt Cancer Center.
Alison A. Motsinger-Reif, PhD
Motsinger-Reif’s research at North Carolina State University is focused on pharmacogenetics and bioinformatics.
Jai Narendra Patel, PharmD
Patel is the chief of Pharmacology Research in the Department of Cancer Pharmacology and an associate professor in the Division of Hematology/Oncology at Atrium Health’s Levine Cancer Institute. Patel oversees cancer pharmacology and pharmacogenomics research.
Nita Patel, PhD
Patel is a senior research advisor at Eli Lilly and Company. Dr. Patel has 20+ years of drug discovery and development experience optimizing compounds for drug metabolism/transporter interactions, pharmacokinetics and understanding PKPD relationships in pharmacology.
Kenneth Phares, PhD
Phares has extensive experience in the pharmaceutical industry, specifically in the areas of pre-formulation, formulation development, and bioanalytical method development.
Mathew T. Pletcher, PhD
Pletcher is the head of Rare Disease Discovery at Roche. His research is focused on genetics, pharmacogenomics, drug development, and genomic medicine.
Bob Powell, PharmD
Powell is a clinical pharmacologist who is interested in developing better dosing strategies in emerging markets with the goal of making drugs safer and more effective.
Virginia Schmith, PhD, FCP
Schmith provides expert consulting in clinical development and pharmacometric strategies for compounds from candidate selection through registration and beyond; development, implementation, and interpretation of strategies for PK/PD and modeling and simulation; participating in regulatory meetings; and evaluating the probability of successful differentiation from competitors.
Todd Schwartz, DrPH
Schwartz is an associate professor of biostatistics at the UNC Gillings School of Global Public Health. His efforts are focused on supporting various research projects across Health Affairs at UNC with regard to their biostatistical aspects, including consultation on design, conduct, analysis, and dissemination.
Russell Thomas, PhD
Thomas is the director for the EPA’s National Center for Computational Toxicology and Exposure. His research is focused on developing more efficient ways to evaluate the safety of chemicals.
Jian Wang, PhD, MSRS, FCP
Wang is an associate director for regulatory science in Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration. He has many years of working experience in drug development, clinical pharmacology, and regulatory science.
Daniel Weiner, PhD
Weiner is a private drug development consult and a part-time faculty with DPET. His expertise is in the field of pharmacometrics and pharmaceutical biostatistics.
Maciej Jan Zamek-Gilszczynski, PhD
Zamek-Gilszczynski is a senior fellow and director at GlaxoSmithKline. His research focuses on clinical drug development.
Darryl C. Zeldin, MD
Zeldin is the NIEHS Scientific Director and is responsible for one of the largest intramural research programs at the NIH with over 1000 scientists in 10 Departments and 15 Core Facilities, and an annual budget of over $130M. He is an internationally recognized expert on eicosanoids (lipid mediators) and their role in regulating cardiovascular function, and on environmental causes of asthma.
Zhiyang Zhao, PhD
Zhao is the chief scientific officer at Alliance Pharma. His area of research is pharmacokinetics and drug metabolism.
DPET Emeritus Faculty
DPET Primary Staff
August/September 2022
- Danny Gonzalez received the 2023 ASCPT Leon I. Goldberg Early Investigator Award, which honors an academic, industrial, or regulatory scientist who has made a substantial contribution to clinical pharmacology within 10 years of the completion of an advanced degree and/or a post-doctoral fellowship or residency program. The award will be presented to Dr. Gonzalez at the ASCPT Annual Meeting in March 2023 (in Atlanta, GA), which will be accompanied by a research presentation.
- Johghwa (Kyle) Lee (postdoc in the Jackson Lab) presented his work titled “Ibrutinib metabolism in vitro is correlated with hepatic CYP3A expression and activity and plasma 4β-hydroxycholesterol/cholesterol ratio” at the International Society for the Study of Xenobiotics (ISSX)/Microsomes and Drug Oxidations (MDO) 2022 Meeting in Seattle and was awarded 2nd place for the best presentation in the postdoctoral category.
- Gauri Rao received a NIH/NIAID R01 grant for her project titled, “Development of a broad spectrum teixobactin-lipopeptide hybrid for the treatment of lung infections caused by pan-drug resistant ‘superbugs.’” The funding will provide $3.6M in research funding over a 5-year period.
- Dan Crona was selected as an author on the Clinical Pharmacogenomics Implementation Consortium (CPIC) guideline update for CYP3A5/tacrolimus.
- Dennis Williams was selected as Vice Chair for the Geriatric Pharmacy Specialty Council for the Board of Pharmacy Specialties (BPS) beginning in 2023.
- Benyam Muluneh is the UNC site Co-PI on a 5-year international collaborative NIH/NCI U01 grant titled, “Adapting a point of the use test card, the chemoPAD, for protecting chemotherapy drug quality in sub-Saharan Africa.” The UNC site was awarded $667K of the $2.7M overall project award.
- Jo Ellen Rodgers has been nominated and selected as the recipient of this year’s ACCP Cardiology PRN Lifetime Achievement Award. Dr. Rodgers will be recognized for this outstanding achievement at the October 2022 ACCP Global Conference on Clinical Pharmacy in San Francisco.
June 2022
- Fifth-year graduate student Jessica Beers was selected as a recipient of the AFPE Pre-Doctoral Fellowship in Pharmaceutical Sciences. She was selected from a highly accomplished pool of applicants.
- Second-year graduate student Meethila Gade, MPH, was accepted into the Cold Spring Harbor Laboratory (CSHL) Single Cell Analysis Course and received a scholarship from Regeneron to help cover the course fee. CSHL offers this highly competitive course to teach students cutting-edge wet-lab approaches for single cell analysis and to provide familiarity with basic bioinformatic approaches to single cell data.
May 2022
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Benyam Muluneh served on a multidisciplinary guideline panel to develop recommendations on Oral Chemotherapy Adherence for Oncology Nursing Society (ONS). The guideline is available at: https://onf.ons.org/ons-guidelines-support-patient-adherence-oral-anticancer-medications. Sarah Belcher (University of Pittsburgh), Emily Mackler (Michigan Oncology Quality Consortium) and Benyam served as leads for the guideline.
- Two DPET faculty members were honored at the 2022 Awards Ceremony: Adam Persky for PY1 Instructor of the Year and Dennis Williams for PY3 Instructor of the Year. In addition, PharmD student JB Collins received the DPET award for demonstrating a high degree of professional motivation and and has generated and disseminated new knowledge in pharmacotherapy and/or accelerated its application to improve patient care.
- Adam Persky (in collaboration with UNC Eshelman School of Pharmacy faculty members Kathryn Fuller and Nicole Pinelli) received the 2022 Award for Excellence in Assessment from the American Association of Colleges of Pharmacy (AACP). The award acknowledges an assessment initiative or project that improves a PharmD program through continuous quality improvement. Their project entry focused on their Redesigned Entrustable Professional Activity Assessments in Pharmacy Practice Experiences.
March/April 2022
- Research performed by the Gonzalez lab in collaboration with Duke University and the Pediatric Trials Network resulted in medication label change for diazepam use in pediatric patients 3 months to 17 years of age, and a separate medical label change that added dosing information for clindamycin use in premature and term infants. Danny Gonzalez spent a large portion of his T32 fellowship training and first year on faculty working on these analyses.
- Craig Lee is first author on a recently published Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 Genotype and Clopidorgrel Therapy
- Jo Ellen Rodgers, along with her colleague Dr. Craig Beavers, led a writing group in developing a statement titled Cardio-oncology Drug Interactions: A Scientific Statement from the American Heart Association. The statement addresses the importance of drug interactions used in managing cardiovascular disease in patients with cancer.
- Four DPET trainees received $200 travel awards at the 2022 Pharmaceutical Sciences Research & Graduate Education Retreat. Jiawei Zhou (fourth-year grad student) won for Best 3-minute Thesis Presentation. Jessica Beers (fourth-year grad student) won a Best Poster Award. Tyler Dunlap (industry fellow) won for Best Podium Presentation. Preston Skersick (industry fellow) won a Best Poster Award.
February 2022
- Bill Zamboni has been promoted to Professor effective 3/15/22.
- Kim Brouwer was recognized by UNC for 35 years of service with the state of North Carolina.
- Bob Dupuis was recognized by UNC for 35 years of service with the state of North Carolina.
- Craig Lee was recognized by UNC for 15 years of service with the state of North Carolina.
- Klarissa Jackson received the 2022 ASPET Division for Translational and Clinical Pharmacology Early Career Award. The award recognizes excellence in translational and clinical pharmacology research that comes from early career scientists. Klarissa was chosen for her work with translational research in drug metabolism/toxicology on individual variations of cytochrome P450 enzymes that aim to elucidate the mechanisms of and risk factors for adverse drug reactions. She will receive the award at the ASPET Annual Meeting in Philadelphia in April.
- Bill Zamboni was appointed as a member of the Pharmaceutical Science and Clinical Pharmacology Advisory Committee of the US Food and Drug Administration.
- Jiawei Zhou is the recipient of this year’s Heyward Hull Travel Award. She will receive funding for an upcoming conference.
- Carter Cao and SOM collaborator Justin Milner have won the 2021 Intersect Fellowship Award from The American Association of Immunologists. The proposal title is: Driving T cell residency and functionality in pancreatic ductal adenocarcinoma.
January 2022
- Julie Leemkuil won the “Positivity Award (Staff Impact Awards)” at the December Staff Holiday Event. This award is for the person who is upbeat and exhibits the can-do spirit. Talking to this person never fails to brighten your day because they exhibit respect and kindness always.
- Sontina Greene won the “Making a Difference (Staff Impact Awards)” at the December Staff Holiday event. This person fosters morale and helps build a sense of community. They embrace diversity and inclusion of thought, backgrounds, and experiences that adds to the richness the School brings to the community.
- Anh Nguyen and Julia Quintanilha has been selected as ASCPT Presidential Trainees. Anh is a Drug Development Fellow with the Lee lab and Julia is a post-doc with the Wiltshire lab.
- Bethany Latham, a 2nd year graduate student was recognized as the 3rd place winner for her 3-minute presentation at the PharmAlliance Graduate Research E-Symposium.
- Chitra Saran, a BBSP student in the Brouwer Lab has been selected as the Journal of Pharmacology and Experimental Therapeutics Highlighted Trainee Author for February 2022.
December 2021
- Carter Cao was selected for a UNC Computational Medicine Program Pilot Award for his proposal titled Adaptive Vaccination: Model-informed peptide selection for neoantigen booster vaccines.
- Danny Gonzalez, in collaboration with the BPCA Framework to Enable Pediatric Drug Developing Assemblies Team, have been selected to receive a National Institute of Child Health and Human Development (NICHD) Collaboration Award. The Collaboration Award recognizes individuals who have advanced the Institute’s mission through successful collaboration with partners across NICHD or outside the Institute.
- Gauri Rao in collaboration with Dr. Jian Li has received an R21 NIH/NIAID award for their project titled Towards the Translation of Synergistic Phage-Polymyxin Combination Therapy against Pandrug-resistant Klebsiella pneumoniae: A Systems Approach.
- Gauri Rao in collaboration with Dr. Babu Tekwani has received a grant from Southern Research Institute for their project titled Evaluation of Therapeutic Product Candidates in Bacterial in vitro Hollow Fiber Models.
- Bill Zamboni in collaboration with Vickie Bae-Jump have received an NIH R21 award for their project titled Phase 1 Clinical Trial of Atezolizumab+ ONC201 using an Innovative Trial Design Parallel Cohorts of Obese and Non-Obese Patients with Metastaic/Recurrent Endometrial Cancer
November 2021
- Carter Cao was promoted to Associate Professor with Tenure
- Dean Angela Kashuba gave the inaugural Charles Boucher Memorial Lecture for the International Workshop on Clinical Pharmacology of HIV, Hepatitis, and Antivirals. This conference took place September 20th– September 22nd, 2021. Her presentation was titled “Contributions of Pharmacology to HIV Cure”. (October 2021)
- Kim Brouwer, in collaboration with Tom Kralj and Darren Creek, created a figure for their paper titled “Creek Analytical&Omics-Based Advances in Study of DILI Toxicol Sci 183.1-13, 2021” which was selected to be on the cover of the September issue of Toxicological Sciences.
- Dan Crona was awarded an American Cancer Society (ACS) Research Scholar Grant for his work with Nate Hathaway and the dCas9-FKBP-CEM system and this grant will focus on repressing EPAS1 and activating VHL in kidney cancer.
- Benyam Muluneh in collaboration with Katie Buhlinger, John Valgus, Maurice Alexander, Stephanie Jean and Suzanne Francart received the “Best Practice Award” by ASHP. They submitted an innovative model on managing Acute Myeloid Leukemia patients in the outpatient setting with intensive pharmacy support (for clinical monitoring) and advance technician roles (for drug access).
- Dan Weiner received the 2022 Sheiner-Beal Pharmacometrics Award from ASCPT and he will be recognized during the 2022 ASCPT Annual Meeting which will take place March 16-18, 2022. (October 2021).
- Jessica Beers, a 4th year graduate student, was selected as the Highlighted Trainee Author for the journal Drug Metabolism and Disposition for the October 2021 issue.
- Anh Nguyen, a 1st year PPD Clinical Research/Drug Development Fellow was awarded an ASCPT Presidential Award for her abstract titled “Investigation of Cardiovascular Outcomes in black patients following implementation of CYP2C19 Genotype-guided Antiplatelet Therapy in a Real-World Clinical Setting.
- Julia Quintanilha, a post-doc in the Wiltshire Lab was awarded an ASCPT Presidential Trainee Award for her abstract titled “Polygenic Risk Scores for blood pressure may predict risk of severe Bevacizumab-induced hypertension in cancer patients”.
September 2021
- Mackenzie Cottrell received a two year R21 award for her proposal titled “Accelerating to the Cure: A Novel IVIVE Model for Advancing HIV Eradiction Strategies”.
- Dan Crona received a second 3-yr grant from DoD for his proposal titled “Discovery of a First-in-Class MPP8 Antagonist to Reverse Lineage Plasticity in Bladder Cancer” and a DoD grant for “Discovery of a First-in-Class MPP8 Antagonist to Reverse Lineage Plasticity in Treatment-Resistant Prostate Cancer.
- Dan Crona received a grant from NIH/NIGMS Phase 1 for his grant titled “Site-specific epigenetic activation of TP53 to improve cancer therapy”.
- Jacob Robinson, a RASP student who works in the Crona Lab, was awarded an AFPE Gateway to Research grant. He was the only UNC student to win this award.
- Timothy Qi a first year graduate student has been named a Venture Catalyst Fellow for 2021-2022. He is one of ten UNC Graduate Students chosen for this program that provides fellows with business development skills in a real-world setting.
July 2021
- Herb Patterson was selected as the 2021 Fred M. Eckel Pharmacy Leadership Award Recipient.
June 2021
- Julie Dumond was promoted to Associate Professor with tenure effective July 1, 2021.
- Craig Lee was promoted to Professor with tenure effective July 1, 2021.
- Dan Crona received a 3-year grant from DoD for his proposal titled “Discovery of a First-In-Class MPP8 Antagonist to Reverse Lineage Plasticity in Treatment-Resistant Prostate Cancer”.
- Rachel Church and Merrie Mosedale were selected to receive a 2021 Burroughs Wellcome Fund Center Career Guidance for Trainees awards. The title of their proposal is “Micro-Credentials to Support Career Readiness for Pharmaceutical Industry Roles”. This award will be used to develop a micro-credential for the Ph.D. students from the “Fundamentals of Regulatory Affairs” course in the Regulatory Science Master’s Program.
- Danny Gonzalez, has been selected as the first Hartmut Derendorf Young Investigator Lecture Award Winner. This annual award recognizes a meeting presenter who is also a young investigator at the Marbach Castle-Drug Interaction Workshop. Dr. Hartmut Derendorf was a Distinguished Professor Emeritus at The University of Florida, College of Pharmacy. He was considered one of the “fathers” of modern pharmacokinetics and pharmacometrics.
- Ricardo Gonzalez, a fourth-year graduate student has been selected as the Elliot S. Vesell Award Winner for the 2021 Virtual Annual Meeting of the American College of Clinical Pharmacology (ACCP). The title of his abstract is “ Functional Follow-up of GWAS Associated SNP Effects in the RYK and MKXAS1 Genes Associated with Drug Response Variation of Monotherapy Temozolomide and Oxaliplatin”.
- Eric Mui, PharmD and Riddhi Virparia, PharmD, second year Regulatory Affairs Fellows at GSK published their co-authored paper entitled “Analysis of the Real-Time Oncology Review (RTOR) Pilot Program for Approvals of New Molecular Entities” in Therapeutic Innovation & Regulatory Science.
- Patty Maglalang, PharmD, a rising first-year student received an AFPE-Phi Lambda Sigma (PLS) First Year Graduate Research Fellowship in the amount of $7500.
May 2021
- Julie Dumond received a 5-year NIH R01 grant in the amount of $3.5 million for her proposal titled Quantifying Sex-and-Age Related Differences in Antiretroviral Exposure and Adverse Effects in the MACS/WIHS Combined Cohort Study.
- Daniel Gonzalez received a 5-year NIH grant for his proposal titled Application of Physiologically-Based Pharmacokinetic Modeling to Characterize Drug-Drug Interactions in Infants.
- Bill Zamboni in collaboration with Dr. David Lawrence received a 4-yr NIH grant for their proposal titled “Design and Application of Photoresponsive Modules in Circulating Erythrocytes.”
- Adam Persky was named the Eshelman School of Pharmacy “PY1 Instructor of the Year” award.
- Aaron Devanathan, a fourth-year graduate student has been selected to received a Royster Society of Fellows Dissertation Completion Fellowship for the AY2021-2022. He has also been selected as an American Foundation for Pharmaceutical Education (AFPE) Award recipient.
- Daisy Zhu, a fourth-year graduate student has been selected as a recipient for the P.E.O. Sisterhood Award for Women in Science. She is one of 100 doctoral students in the U.S. and Canada selected to receive a $20,000 Scholar award. She has also been selected as an American Foundation for Pharmaceutical Education (AFPE) Award recipient.
- Spinel Karas, a fourth-year graduate student has been selected for a GSK Fellowship and a T-32 Fellowship in Clinical Pharmacology.
- Jiawei Zhou, a third-year graduate student has been selected for a GSK Fellowship.
- Jessica Beers, a third-year graduate student has been selected for a T-32 Fellowship in Clinical Pharmacology.
April 2021
- Bill Zamboni received a NIH National Cancer Institute (NCI) R01 grant for his proposal titled Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors.
- Julia Quintanilha, a post-doctoral research associate, received a post-doctoral fellowship with the American Heart Association(AHA) for her proposal entitled Genetic Modifiers of Drug-Induced Hypertension for Risk Assessment of Patients Treated with VEGF-Pathway Inhibitors. The one-year fellowship provides Dr. Quintanilha with $67K in funding.
- Danny Gonzalez has been recognized as one of the “40 Gators under 40 for 2021”. This award honors the University of Florida, Outstanding Young Alumni whose achievements positively impact their communities and professions.
March 2021
- Dr. Klarissa Jackson along with Carla White and Suzie Harris was awarded a grant by Genentech, Inc. This grant is for their project titled “Well-Being Initiative for Woman Faculty of Color to Promote Professional Advancement in Pharmacy and Pharmaceutical Sciences Research.” This award is in the amount of $386,895.25.
- Dr. Jo Ellen Rodgers has been appointed the Director of Postdoctoral Programs for the School of Pharmacy (effective March 1, 2021). In this role she will be responsible for overseeing the postdoctoral training for the school.
February 2021
- Dr. Benyam Muluneh has been selected as a KL2 Scholar with the TraCS KL2 Program starting on July 1, 2021.
- Dr. Merrie Mosedale has been awarded the 2021 Junior Faculty Development Award from the Provost’s Office for her proposal: “Development of High-Content Imaging Assays for In-Vitro Mouse Genetics Platform”.
- Dr. Merrie Mosedale passed the Regulatory Affairs Certification (RAC) Exam for Drugs in December 2020 and now holds the RAC Credential.
January 2021
- Dr. Benyam Muluneh’s perspective piece co-authored with Stacie Dusetzina, Nancy Keating and Haiden A. Huskamp “Broken Promises-How Medicare Part D has Failed to Deliver Savings to Older Adults” was published in the New England Journal of Medicine.
- Dr. Kim Brouwer, Danny Gonzalez and team received a perfect impact score of 10 on their 2nd NICHD Pediatric Clinical Pharmacology T32 application.
- Dr. Mackenzie Cottrell and the UNC CFAR Pharmacology Core, along with the UNC CFAR received a perfect score on their competitive renewal. This is the first time ever a CFAR has received a score of 10.
December 2020
- Dr. Benyam Muluneh’s perspective piece co-authored with Stacie Dusetzina “Broken Promises — How Medicare Part D Has Failed to Deliver Savings to Older Adults” was published in the New England Journal of Medicine.
November 2020
- Dr. Herb Patterson received the ACCP Cardiology Practice & Research Network (PRN) Lifetime Achievement Award, which recognizes a PRN member who has consistently contributed “above and beyond” to the PRN, to cardiovascular pharmacotherapy, and to the advancement of cardiovascular clinical pharmacy practice during their career.
October 2020
- Dr. Gauri Rao received a 2 year DoD grant of $1,888,916 for “Novel Antimicrobial Hybrid Hydrogel Dressing Targeting Wound Infections Caused by Superbugs Resistant to All Current Antibiotics.”
- Dr. Jacqueline Bezençon received a $165,167 grant to investigate the “Effect of Overt Type 2 Diabetes and Metformin Treatment on Placental Transport Proteins” in humans funded by an administrative supplement to Kim Boggess’ NICHD R01 grant.
September 2020
- Dr. Julie Dumond received a NIH Award for the project “Quantifying Sex-and-Age-Related Differences in Antiretroviral Exposure and Adverse Effects in the MACS/WIHS Combined Cohort Study” for the amount of $567,218.
August 2020
- Dr. Carter Cao received a UNC Lineberger Innovation Award for the project “ Measuring CAR T cell–tumor cell interactions in vivo to overcome resistance to CAR-T therapy in solid tumors” for the amount of $150,000 over 2 years.
July 2020
- Dr. Erin Heinzen was awarded a RO1 grant titled “Defining disease mechanisms in SLC35A2 epilepsy” in the amount of $732,007.
- Dr. Craig Lee received funding from NHLBI/NIH for a Multiple PI RO1 grant with Larisa Cavallari (University of Florida) titled “Precision Antiplatelet Therapy after Percutaneous Coronary Intervention.” Total funding is $3.5M over 5 years ($1.25M to UNC).
- Dr. Kim Brouwer received funding for the NIGMS T32 Administrative supplement to Enhance Program Evaluation Capacity grant.
June 2020
- Dr. Gauri Rao is the recipient of the Friends Fighting Cystic Fibrosis award of $30,000 through the UNC School of Medicine.
May 2020
- Dr. Craig Lee received funding for an RO1 grant “Mechanisms of Altered Hepatic Drug Metabolism and Transport in Pregnancy” from NICHD/NIH, with total funding of $1,643,385 over 4 years.
- Dr. Federico Innocenti was awarded a $200k Alliance Special Projects Allocation Award for a proposal entitled “Machine learning prognostic and predictive analyses for metastatic colorectal cancer – C80405.”
- Dr. Amber Cipriani has been named as a one of the 2020 Experiential Precepting Stars for UNC Medical Center and UNC Eshelman School of Pharmacy.
March 2020
- Dr. Craig Lee, Dr. Alexis Williams (2nd year fellow), and Dr. Rick Stouffer published “Frequency and clinical outcomes of CYP2C19genotype-guided escalation and de-escalation of antiplatelet therapy in a real-world clinical setting” in the January issue of Genetics in Medicine. The Genomic Medicine Working Group of the National Advisory Council for Human Genome Research of the National Human Genome Research Institute (NIH/NHGRI) highlighted this paper as one of the top 10 advances in genomic medicine in 2019.
- Dr. Klarissa Jackson’s $50k “Phenotypic Biomarkers of Cytochrome P450 3A for Precision Dosing in Chronic Lymphocytic Leukemia” grant has been chosen for funding by NC TraCS.
January 2020
- Dr. Andrew Lucas received the 2020 Junior Faculty Development Award for $10,000 from the UNC Committtee on Faculty Research and Scholarly Leaves.
- Drs. Gauri Rao was awarded the PharmAlliance Grant (MONASH-UNC) of $50,000: Big data approach analyzing clinical and genomic data combined with in vitro pharmacokinetic/pharmacodynamic modelling: towards precision therapy for life-threatening infections.
- Dr. Merrie Mosedale was presented with the 2020 ASPET Early Career Award.
November 2019
- Dr. Kim Brouwer was invited to present in the opening session of the NASH and Cholestatic Liver Disease Meeting that the Duke-Margolis Center for Health Policy is jointly organizing with the U.S. FDA.
October 2019
- Dr. Angela Kashuba will be receiving one of the American Society for Clinical Pharmacology and Therapeutics’ most prestigious awards, the Rawls-Palmer Progress in Medicine Award. She will be acknowledged during the 2020 ASCPT Annual Meeting in Houston, TX.
- Dr. Dennis Williams received the APhA Foundation’s Bowl of Hygeia Award during the NCAP Convention this past week. This annual award is given in each state for a pharmacist based on their contributions to the profession and community.
- Dr. Benyam Muluneh had a paper selected for a Journal of Oncology Pharmacy Practice (JOPP) Best Paper Award in the Research Article category. The article is entitled, “Patient Perspectives on the Barriers Associated with Medication Adherence to Oral Chemotherapy” and was published in the March 2018 issue of the JOPP.
- Dr. Jo Ellen Rodgers was selected to participate in an American College of Cardiology – Heart House Roundtable called the Cardio-Oncology: Risk Assessment & Management Strategies Roundtable.
September 2019
- Dr. Julie Dumond has received another NIH R21 from the National Institute of Aging. Her project is titled “Interaction of Nucleoside Reverse Transcriptase Inhibitor Pharmacology and Aging in the Multicenter AIDS Cohort Study.”
- Dr. Bill Zamboni has received a C-CCNE Pilot Grant for his proposal “Modulation of Tumor Fibroblasts by MRX-2843 to Increase the Tumor Delivery and Efficacy of Nanoparticles in In Vivo and In Vitro 3D Tumor Models.”
- Dr. Carter Cao had a program proposal titled “Overcoming Tumor Resistance in Cancer Therapy: Applying Evolutionary Principles from Bench to Bedside” accepted at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) 2020 Annual Meeting, March 18-21, 2020.
August 2019
- Dr. Gauri Rao has received an NIH R01 from the National Institute of Allergy and Infectious Diseases. Her project is titled “Pharmacology of intrathecal/intraventricular polymyxins: A systems-based approach.”
- Dr. Gauri Rao has received a Center for AIDS Research (CFAR) supplement award for a project entitled, “The Relationship between Pyrazinamide Pharmacokinetics, Tuberculosis Disease, and Host Immune Responses.”
- Dr. Craig Lee has been selected to participate as an author on the CYP2C19/clopidogrel Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline update.
- Dr. Dan Crona and Mackenzie Cottrell have both received NIH Loan Repayment Programs Awards. This award is designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers.
June 2019
- Dr. Kim Brouwer was distinguished as Inventor of the Year during the 2019 UNC Celebration of Inventorship. The UNC Office of Technology Commercialization presents the Inventor of the Year Award to a UNC-Chapel Hill innovator in recognition of their contributions to inventions and patents. The award honors the recipient’s commitment to the University’s culture of encouraging innovation, disseminating knowledge, and promoting entrepreneurship.
- Dr. Dan Crona has received a Translational Tier 2 Eshelman Institute for Innovation Award for his project entitled, “Chemically catalyzed epigenetic gene regulation in prostate cancer.”
- Dr. Merrie Mosedale has received an NIH R21 from the Office of Research Infrastructure Programs and is entitled, “Development of an in vitro mouse genetic reference platform to improve preclinical drug safety assessment.” The goal of the research is to evaluate the utility of an in vitro platform developed from the Collaborative Cross mouse population to improve preclinical safety assessment and identify interspecies differences in drug toxicity between animals and humans.
- Dr. Rachel Church won the best poster award at the AASLD-FDA Drug-Induced Liver Injury Conference for the most outstanding DILI poster.
May 2019
- Dr. Jo Ellen Rodgers has been selected to be a member of the American Heart Association, Cardio-Oncology Science Subcommittee.
April 2019
- Dr. Dan Crona has received a HOPA Early Career Research Grant for his project entitled: “Precision Dosing of TKIs for Real World Patients with Chronic Myelogenous Leukemia”. The HOPA Early Career Research Grant (ECR) provides funding to promising investigators early in their career to encourage and promote quality basic and pre-clinical translational lab-based research in oncology.
- Dr. Amanda Corbett has been selected to participate in the Mary Frances Picciano Dietary Supplement Research Practicum through the Office of Dietary Supplements. This intensive practicum will provide a thorough overview and grounding about issues, concepts, unknowns, and controversies about dietary supplements and supplement ingredients. It will also emphasize the importance of scientific investigations to evaluate the efficacy, safety, and value of these products for health promotion and disease prevention as well as how to carry out this type of research.
- Dr. Mackenzie Cottrell has received a 12 on her R21 NIH/NIAID grant application. The title of the submitted grant is “Feminizing Sex Hormones Impact on PrEP Pharmacology in Transgender Women”.
- Dr. Paavo Honkakoski, a global expert on nuclear receptors, has returned to the UNC Eshelman School of Pharmacy as a recipient of the Nannerl O. Keohane Distinguished Visiting Professorship in 2019-20. Honkakoski is a professor of Biopharmacy at the School of Pharmacy and Faculty of Health Sciences at the University of Eastern Finland. DPET is serving as the sponsoring unit for Prof. Honkakoski’s visit.
February 2019
- Dr. Federico Innocenti has received supplemental funding from the Alliance for Clinical Trials in Oncology Foundation in support of his work associated with Alliance protocol CALGB 80802, “A Phase III Randomized Study of Sorafenib plus Doxorubicin versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma (HCC) – CALGB 80802 and Correlative Substudy – CALGB 150902.”
January 2019
- Dr. Dan Crona received a Junior Faculty Development Award. His project is entitled, “Evaluation of combined PARP and BET inhibition in preclinical models of urothelial bladder cancer.”
Kim Brouwer
- Mechanisms of Altered Hepatic Transport: Impact on Drug Therapy
NIH National Institutes of Health (NIH), 4/1/2022-3/31/2027
Mackenzie Cottrell
- Delivery of Antiretrovirals via Implantable System for Young children (DAISY)
NIH National Institute of Allergy and Infectious Diseases (NIAID), 3/15/20-2/28/23 - Impact of Concomitant Chemotherapy on HIV Resistance to cART and Reservoir Size
NIH National Cancer Institute (NCI), 1/8/2019-12/31/2023 - Accelerating to the Cure: A Novel IVIVE Model for Advancing HIV Eradication Strategies
NIH National Institute of Allergy and Infectious Disease (NIAID), 8/12/21-7/31/23 - GM3 Nanoparticles for Sustained Delivery of Anti-Retrovirals to Lymphatic Tissues
NIH National Institute of Allergy and Infectious Diseases (NIAID), 11/1/19-10/31/22
Daniel Crona
- Discovery of a First-In-Class MPP8 Antatgonist to Reverse Lineage Plasticity in Bladder Cancer
Department of Defense (DOD), 9/15/21-9/14/24 - Chemically Catalyzed Epigenetic Gene Regulation in Renal Cell Carcinoma
American Cancer Society (ACS), 1/1/22-12/31/25
Julie Dumond
- Quantifying Sex-and-Age-Related Differences in Antiretroviral Exposure and Adverse Effects in the MACS/WIHS Combined Cohort Study
NIH National Institute of Allergy and Infectious Diseases (NIAID), 4/9/2021-3/31/2026
Daniel Gonzalez
- Physiologically-Based Pharmacokinetic Modeling to Guide Drug Dosing in Children with Obesity (5R01HD096435-02)
NIH/NCICHD, 9/1/2018-7/31/2023 - Application of Physiologically-Based Pharmacokinetic Modeling to Characterize Drug-Drug Interactions in Infants
NIH National Institute of Child Health and Human Development (NICHD), 5/1/2021-4/30/2026
Erin Heinzen
- Defining disease mechanisms in SLC35A2 epilepsy
NIH National Institute of Neurological Disorders and Stroke (NINDS), 7/1/2020-4/30/2025 - Somatic Mutation in Intractible Focal Epilepsy 3(GG015295-01)
NIH National Institute of Neurological Disorders and Stroke (NINDS), 8/15/2020-7/31/2025
Klarissa Jackson
- Interindividual Variability in Drug Metabolism in Ethnically Diverse Populations
NIH National Institute of General Medical Sciences (NIGMS), 7/1/2021-6/30/2026 - An In Vitro Investigation of the Metabolism, Pharmacokinetics, and Hepatotoxicity of Cannabidiol
American Foundation for Pharmaceutical Education (AFPE), 9/1/2022-8/31/2023
Craig Lee
- Mechanisms of Altered Hepatic Drug Metabolism and Transport in Pregnancy (1R01HD098742-01) NICHD/NIH, 04/01/2020 – 03/31/2024
- Precision antiplatelet therapy after percutaneous coronary intervention
NIH National Heart, Lung, and Blood Institute (NHLBI), 7/15/2020-6/30/2025
Gauri Rao
- Development of a broad spectrum teixobactin-lipopeptide hybrid for the treatment of lung infections caused by pan-drug resistant ‘superbugs’
NIH National Institute of Allergy and Infectious Diseases (NIAID), 6/21/2022-5/31/2027
- Pharmacology of Intrathecal/Intraventricular Polymyxins: A Systems-Based Approach (1R01AI146241-01)
NIAID, 7/8/2019-6/30/2024 - Advancing innovative therapies against pandrug-resistant Gram-negative superbugs
NIH National Institute of Allergy and Infectious Diseases (NIAID), 7/1/1022-6/30/2024 - Facilitating the Translation of Synergistic Phage-Polymyxin Combination Therapy against Pandrug-resistant Klebsiella pneumoniae using a Systems Approach
NIH National Institute of Allergy and Infectious Disease (NIAID), 8/16/21-7/31/23
Paul Watkins
- Coordinating Center for Drug Induced Liver Injury Network (DILIN)
NIH National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDKD), 8/21/2018-6/3/2023 - AAV toxicity to hepatocyte spheroids
Bayer HealthCare, 8/21/2022-2/28/2023 - AAV8 induced toxicities in primary human hepatocytes with MTM1 deficiency using spheroid culture model
Audentes Therapeutics, 6/2/2022-6/1/2023
William Zamboni
- Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors
NIH National Cancer Institute (NCI), 4/1/2021-3/31/2026 - A Triple Quadrupole LC-MS/MS System for Bioanalytical Studies Supporting the Translational Development of Complex and Small Molecule Agents
North Carolina Biotechnology Center (NCBC), 5/31/22-5/30/23