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A career full of family, opportunities and “accidental” success

November 22, 2023

Stephen Eckel, BSPharm ‘95, Pharm.D. ‘97, M.H.A. ‘05, associate dean for global engagement and associate professor in the Division of Practice Advancement and Clinical Education at the UNC Eshelman School of Pharmacy, often tells his students to hold their careers with an open hand.   He recently received the Individual Award for Career Achievement at the American Pharmacists Association (APhA) 2023 Pinnacle Awards, which highlighted his career of advancing the medication use process. Eckel also leads a two-year Master of Science concentrating in Health-System Pharmacy Administration. In addition to his roles at the School, he serves as residency program director for … Read more


Incorporating career exploration and professional development into Ph.D. training: an NSF Innovations in Graduate Education award

October 25, 2023

Assistant Dean Michael Jarstfer and Associate Professor Jacqui McLaughlin are working together to ensure Ph.D. programs offer students contemporary professional development and opportunities for career growth.  To start this effort, a three-year National Science Foundation (NSF) Innovations in Graduate Education grant, of almost $500,000, was awarded to this project. Michael Jarstfer, Ph.D., Assistant Dean for Graduate Education at the UNC Eshelman School of Pharmacy and associate professor in the Division of Chemical Biology and Medicinal Chemistry is the principal investigator of this project.   “Ph.D. training has largely followed an apprenticeship model over the last 100 years. The result is that … Read more


New center to help advance placenta and fetal health

October 23, 2023

The UNC Eshelman School of Pharmacy is partnering with Rutgers University, Tulane University, the University of Pennsylvania and the University of Rochester to launch the Integrated Transporter Elucidation Center (InTEC) supported by a $5 million grant from the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) of the National Institutes of Health (NIH).   The goal of InTEC is to better understand the placental transport proteins involved in the prenatal disposition of nutrients, drugs and toxic chemicals. This work will support drug development and post-marketing drug safety for medications used during pregnancy.  “We will fill the knowledge … Read more


Research on extracellular vesicles will help in the fight against cancer

October 2, 2023

Juliane Nguyen, Ph.D., is studying how exosomal ribonucleic acid (RNA) cargo contributes to progression in cancer and other diseases. Nguyen is a professor and vice chair in the Division of Pharmacoengineering and Molecular Pharmaceutics at the UNC Eshelman School of Pharmacy. She also serves as director of graduate admissions.  Nguyen will continue this research through a $1.6 million research project grant (R01) from the National Institutes of Health (NIH). This research project is in collaboration with Klaus Hahn, Ph.D., Ronald G. Thurman Distinguished Professor in Pharmacology at the UNC School of Medicine.  RNA is a molecule that is present in … Read more


Improving pediatric brain cancer treatments

September 20, 2023

Alexander “Sasha” Kabanov, Ph.D., Dr.Sci., is researching a new way to treat pediatric brain cancer.  “If successful, our therapy will improve medulloblastoma treatment by replacing the current radiation and chemotherapy with one that is less toxic and more effective,” said Kabanov, Mescal S. Ferguson Distinguished Professor and director of the Center for Nanotechnology in Drug Delivery at the UNC Eshelman School of Pharmacy.  In July, the St. Baldrick’s Foundation, the largest charity funder of childhood cancer research grants, awarded $8.4 million to various researchers. Of those awarded, Kabanov was awarded $200,000 to further his research into medulloblastoma treatments. This grant … Read more


Utilizing AI and machine learning for drug discovery 

September 14, 2023

Alexander Tropsha, Ph.D., is exploring unchartered territory through research into ways artificial intelligence and machine learning can help advance the drug discovery process.   Tropsha, a professor in the Division of Chemical Biology and Medicinal Chemistry at the UNC Eshelman School of Pharmacy and director of the Laboratory for Molecular Modeling, is an expert in the fields of computational chemistry, cheminformatics and structural bioinformatics who works to develop new methodologies and software tools for computer-assisted drug design.   His particular expertise lies in the field of cheminformatics, a discipline where information and informatics methodologies are applied to storing, managing, exploring and exploiting … Read more


Research to help eliminate barriers patients face when taking oral chemotherapy drugs

September 13, 2023

Benyam Muluneh, Pharm.D. ‘10, assistant professor in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC Eshelman School of Pharmacy is starting a new project focused on optimizing the delivery of cancer care for North Carolinian patients taking orally administered chemotherapy drugs.   With the support of a $1 million National Cancer Institute grant, Muluneh’s end goal for the project, which will be piloted in urban community and rural cancer centers, is to better understand the barriers patients face in being able to start and then stay on their oral anticancer drugs, which will lead to a patient-centered intervention that … Read more


Shawn Hingtgen advances his research on pediatric cancer

August 23, 2023

Professor Shawn Hingtgen, Ph.D. will further his research on pediatric brain cancer patients with funding from the Ian’s Friends Foundation for his joint effort with project lead Scott Floyd, M.D., Ph.D., of Duke University around living tissue brain slices.   “Ian’s Friends is an amazing foundation that is changing the lives of children with brain cancer. We are so grateful for all their incredible support over the years,” said Hingtgen. “This new award will allow us to explore exciting new aspects of the living tissue brain slice platform. Working in partnership with Dr. Scott Floyd and his team at Duke University, … Read more


Owen Fenton receives NIH award to help fund research to treat skin cancer

August 9, 2023

Owen Fenton, Ph.D. received the National Institutes of Health (NIH) Trailblazer R21 Award. He will receive a total of $601,122 over three years for his project focused on developing new medicines to treat skin cancer that are safer and more effective than current therapies. This project will be conducted in collaboration with co-investigator Stergios Moschos, M.D., associate professor of medicine at the UNC School of Medicine.  “My group focuses broadly within the field of genetic medicine, with a particular focus on developing mRNA therapies for the treatment of disease. We are excited to receive this award which will enable us … Read more


Eshelman Institute for Innovation establishes research collaboration with Aston University

August 1, 2023

As part of a new collaboration, the Eshelman Institute for Innovation (EII), within the UNC Eshelman School of Pharmacy, will work with Aston University in the U.K. on a three-year project focused on preventing damage caused by swelling of the central nervous system (CNS).  The EII was established in 2014 with a $100 million commitment from Fred Eshelman, Pharm.D, and provides translational grant funding to Carolina faculty for therapeutic research focused on oncology, infectious disease, and neuroscience (including rare diseases); however, the EII welcomes ideas for devices and diagnostics, and other therapeutic areas and services. Through their grant mechanism, the … Read more