Category: Pharmacotherapy and Experimental Therapeutics
Brouwer Honored by the University of Kentucky
September 1, 2006Kim Brouwer, chair of the Division of Pharmacotherapy and Experimental Therapeutics, has been selected as the inaugural recipient of the University of Kentucky Outstanding Graduate Program Alumni for the Pharmaceutical Sciences. The goal of this award is to honor graduates of the University of Kentucky in recognition of their accomplishments and contributions to scholarship, education, and research in the pharmaceutical sciences.
Graduate Students Win AAPS Award
August 21, 2006Maciej Zamek-Gliszczynski and Cory Kalvass, graduate students in the Division of Pharmacotherapy and Experimental Therapeutics, have received the 2006 American Association of Pharmaceutical Scientists Pharmacokinetics, Pharmacodynamics, and Drug Metabolism Award. PPDM recognizes individuals who have significantly contributed to the promotion and dissemination of PPDM principles through exemplary and sustained activities in the achievement of PPDM goals.
McLeod Joins School as Eshelman Professor
July 19, 2006Howard McLeod, PharmD, formerly of Washington University in St. Louis, has been appointed the Fred Eshelman Distinguished Professor in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC School of Pharmacy. He is also the director of the new UNC Institute for Pharmacogenomics and Individualized Therapy and a member of the UNC Lineberger Comprehensive Cancer Center. “Dr. McLeod is one of the pioneers in the field of cancer pharmacogenomics and we are extremely pleased that he has decided to join the faculty,” said Kim Brouwer, PharmD, chair of the division. Richard Goldberg, MD, associate director of UNC Lineberger, said, … Read more
Ghibellini Awarded Travel Grant
July 13, 2006Giulia Ghibellini, a graduate student in the Division of Pharmacotherapy and Experimental Therapeutics, has been awarded a travel grant to attend the 14th North American International Society for the Study of Xenobiotics meeting. Ghibellini’s abstract, “In Vitro Characterization and Pharmacokinetic Modeling of Tc-99m Mebrofenin Hepatobiliary Disposition in Humans” was selected as a finalist in the postdoctoral category in the ISSX award program.
Kashuba Awarded $1.7 Million to Study Drug-Interaction Potential of New HIV Protease Inhibitor
June 19, 2006Angela D. M. Kashuba, PharmD, has been awarded a $1.7 million contract from Boehringer Ingelheim to study the drug-interaction potential of tipranavir, a new HIV protease inhibitor. Protease is an enzyme that HIV needs in order to make new viruses. When protease is blocked, HIV makes copies of itself that can’t infect new cells. According to Kashuba, many individual drug-drug interaction studies have demonstrated tipranavir’s high interaction potential. Kashuba’s novel phenotyping approach will help in understanding the basis for these interactions and will form the groundwork for further exploration of potentially important drug interactions. The title of Kashuba’s project is “Evaluating the Effects of Tipranavir (with Ritonavir) … Read more
Chen Presents Poster at ISPOR Meeting
June 14, 2006Shih-Yin (Sharon) Chen, a second-year doctoral student in the Division of Pharmaceutical Outcomes and Policy, presented her poster “Cost-utility Analysis of Tegaserod for the Treatement of Irritable Bowel Syndrome” at the 11th annual ISPOR meeting in May. Chen’s poster was recognized as “high impact” and was among the top 25 percent eligible for poster awards.
Researchers Link Gene Variation to Coronary Heart Disease
May 24, 2006Research led by Craig Lee, PharmD, a graduate student in the Division of Pharmacotherapy and Experimental Therapeutics, shows that a common genetic variation makes some people more susceptible to coronary heart disease. About 15 percent of all Caucasians have the genetic variation, which is also known as a polymorphism. Those who carry the polymorphism are approximately 1.5 times more likely to have a CHD event, such as a heart attack, than those who do not. “We found that Caucasians who carry this polymorphism, named K55R, were at significantly higher risk of coronary heart disease, independent of other risk factors, like cigarette smoking, diabetes, and hypertension,” said … Read more
DPET News Briefs
April 28, 2006Angela Kashuba, associate professor, has been awarded $1.8 million to evaluate the drug interaction potential of a new HIV protease inhibitor. Bruce Canaday, clinical professor, was installed on March 20 as the 2006-2007 APhA president. Jo Ellen Rodgers, clinical assistant professor, is president-elect, Cardiology PRN. Tim Ives, associate professor, was elected secretary of the AACP Pharmacy Practice Section. Ralph Raasch, associate professor, and Christine Walko, academic fellow, received the PY3 Instructor of the Year Award. Dee Melnyk, clinical assistant professor, was named AHEC Instructor of the Year. Angela Kashuba, associate professor, and Julie Dumond, academic fellow, have received the ACCP Infectious Disease Fellowship Award.
Kos Continues Funding of Cardiology Residency
February 15, 2006Kos Pharmaceuticals provided a $10,000 grant to support the School of Pharmacy’s cardiology specialty residency for the fourth year. T. Don Marsh, PharmD, FASHP, associate director of medical affairs at Kos and former director of pharmacotherapy at the Mountain AHEC, has been instrumental in securing the funding for the program, says assistant professor Jo Ellen Rodgers, PharmD. She is one of the residency’s coordinators along with clinical assistant professor Debbie Montague, PharmD. “There are only a handful of cardiology specialty residencies available in the U.S.,” Rodgers says. “These residencies are critically important, helping us achieve our mission of elevating the … Read more
Kashuba Awarded “Paper of the Year” by SIDP
December 14, 2005A manuscript by associate professor Angela Kashuba has been selected by the Society of Infectious Diseases Pharmacists as “Paper of the Year.” The manuscript is entitled “Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results”. The Society of Infectious Diseases Pharmacists is an association of health professionals dedicated to promoting the appropriate use of antimicrobials. SIDP provides education, advocacy and leadership in all aspects of the treatment of infectious diseases.