1: Bopp SE, Ramachandran V, Henson K, Luzader A, Lindstrom M, Spooner M, Steffy
BM, Suzuki O, Janse C, Waters AP, Zhou Y, Wiltshire T, Winzeler EA. Genome Wide
Analysis of Inbred Mouse Lines Identifies a Locus Containing Ppar-gamma as
Contributing to Enhanced Malaria Survival. PLoS One. 2010 May 28;5(5):e10903.
PubMed PMID: 20531941.

2: Eisener-Dorman AF, Grabowski-Boase L, Steffy BM, Wiltshire T, Tarantino LM.
Quantitative trait locus and haplotype mapping in closely related inbred strains
identifies a locus for open field behavior. Mamm Genome. 2010 May 15. [Epub ahead
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3: Kelly SA, Nehrenberg DL, Peirce JL, Hua K, Steffy BM, Wiltshire T, Pardo
Manuel de Villena F, Garland T Jr, Pomp D. Genetic architecture of voluntary
exercise in an advanced intercross line of mice. Physiol Genomics. 2010 Apr 13.
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4: Lee JM, Zhang J, Su AI, Walker JR, Wiltshire T, Kang K, Dragileva E, Gillis T,
Lopez ET, Boily MJ, Cyr M, Kohane I, Gusella JF, MacDonald ME, Wheeler VC. HA
novel approach to investigate tissue-specific trinucleotide repeat instability.
BMC Syst Biol. 2010 Mar 19;4:29. PubMed PMID: 20302627; PubMed Central PMCID:
PMC2856555.

5: Rakhra-Burris TK, Auman JT, Deverka P, Dressler LG, Evans JP, Goldberg RM,
Havener TM, Hoskins JM, Jonas DE, Long KM, Motsinger-Reif AA, Irvin WJ, Richards
KL, Roederer MW, Valgus JM, Riper M, Vernon JA, Zamboni WC, Wagner MJ, Walko CM,
Weck KE, Wiltshire T, McLeod HL. Institutional profile. UNC Institute for
Pharmacogenomics and Individualized Therapy: interdisciplinary research for
individual care. Pharmacogenomics. 2010 Jan;11(1):13-21. PubMed PMID: 20017668.

6: Schwander M, Lopes V, Sczaniecka A, Gibbs D, Lillo C, Delano D, Tarantino LM,
Wiltshire T, Williams DS, Müller U. A novel allele of myosin VIIa reveals a
critical function for the C-terminal FERM domain for melanosome transport in
retinal pigment epithelial cells. J Neurosci. 2009 Dec 16;29(50):15810-8. PubMed
PMID: 20016096; PubMed Central PMCID: PMC2834289.

7: Grillet N, Schwander M, Hildebrand MS, Sczaniecka A, Kolatkar A, Velasco J,
Webster JA, Kahrizi K, Najmabadi H, Kimberling WJ, Stephan D, Bahlo M, Wiltshire
T, Tarantino LM, Kuhn P, Smith RJ, Müller U. Mutations in LOXHD1, an
evolutionarily conserved stereociliary protein, disrupt hair cell function in
mice and cause progressive hearing loss in humans. Am J Hum Genet. 2009
Sep;85(3):328-37. PubMed PMID: 19732867; PubMed Central PMCID: PMC2771534.

8: Bryant CD, Chang HP, Zhang J, Wiltshire T, Tarantino LM, Palmer AA. A major
QTL on chromosome 11 influences psychostimulant and opioid sensitivity in mice.
Genes Brain Behav. 2009 Nov;8(8):795-805. Epub 2009 Jul 21. PubMed PMID:
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9: Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA,
Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris
C, Contractor T, Wiltshire T, Rusyn I, Threadgill DW. Mouse population-guided
resequencing reveals that variants in CD44 contribute to acetaminophen-induced
liver injury in humans. Genome Res. 2009 Sep;19(9):1507-15. Epub 2009 May 5.
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10: Schwander M, Xiong W, Tokita J, Lelli A, Elledge HM, Kazmierczak P,
Sczaniecka A, Kolatkar A, Wiltshire T, Kuhn P, Holt JR, Kachar B, Tarantino L,
Müller U. A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to
defects in tip links of mechanosensory hair cells. Proc Natl Acad Sci U S A. 2009
Mar 31;106(13):5252-7. Epub 2009 Mar 6. PubMed PMID: 19270079; PubMed Central
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11: Williams R 4th, Lim JE, Harr B, Wing C, Walters R, Distler MG, Teschke M, Wu
C, Wiltshire T, Su AI, Sokoloff G, Tarantino LM, Borevitz JO, Palmer AA. A common
and unstable copy number variant is associated with differences in Glo1
expression and anxiety-like behavior. PLoS One. 2009;4(3):e4649. Epub 2009 Mar 6.
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12: Barouch-Bentov R, Che J, Lee CC, Yang Y, Herman A, Jia Y, Velentza A, Watson
J, Sternberg L, Kim S, Ziaee N, Miller A, Jackson C, Fujimoto M, Young M, Batalov
S, Liu Y, Warmuth M, Wiltshire T, Cooke MP, Sauer K. A conserved salt bridge in
the G loop of multiple protein kinases is important for catalysis and for in vivo
Lyn function. Mol Cell. 2009 Jan 16;33(1):43-52. PubMed PMID: 19150426; PubMed
Central PMCID: PMC2683036.

13: Baile JS, Grabowski-Boas L, Steff BM, Wiltshire T, Churchil GA, Tarantino LM.
Identification of quantitative trait loci for locomotor activation and anxiety
using closely related inbred strains. Genes Brain Behav. 2008 Oct;7(7):761-9.
PubMed PMID: 19130624.

14: Breitling R, Li Y, Tesson BM, Fu J, Wu C, Wiltshire T, Gerrits A, Bystrykh
LV, de Haan G, Su AI, Jansen RC. Genetical genomics: spotlight on QTL hotspots.
PLoS Genet. 2008 Oct;4(10):e1000232. Epub 2008 Oct 24. PubMed PMID: 18949031;
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15: Bailey JS, Grabowski-Boase L, Steffy BM, Wiltshire T, Churchill GA, Tarantino
LM. Identification of QTL for locomotor activation and anxiety using
closely-related inbred strains. Genes Brain Behav. 2008 Jun 30. [Epub ahead of
print] PubMed PMID: 18616613.

16: Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL,
Zhang J, Orth AP, Walker JR, Glynne RJ, Cooke MP, Takahashi JS, Shimomura K,
Kohsaka A, Bass J, Saez E, Wiltshire T, Su AI. Gene set enrichment in eQTL data
identifies novel annotations and pathway regulators. PLoS Genet. 2008 May
9;4(5):e1000070. PubMed PMID: 18464898; PubMed Central PMCID: PMC2346558.

17: Howden R, Liu E, Miller-DeGraff L, Keener HL, Walker C, Clark JA, Myers PH,
Rouse DC, Wiltshire T, Kleeberger SR. The genetic contribution to heart rate and
heart rate variability in quiescent mice. Am J Physiol Heart Circ Physiol. 2008
Jul;295(1):H59-68. Epub 2008 May 2. PubMed PMID: 18456734; PubMed Central PMCID:
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18: Lattin JE, Schroder K, Su AI, Walker JR, Zhang J, Wiltshire T, Saijo K, Glass
CK, Hume DA, Kellie S, Sweet MJ. Expression analysis of G Protein-Coupled
Receptors in mouse macrophages. Immunome Res. 2008 Apr 29;4:5. PubMed PMID:
18442421; PubMed Central PMCID: PMC2394514.

19: Cheli Y, Jensen D, Marchese P, Habart D, Wiltshire T, Cooke M, Fernandez JA,
Ware J, Ruggeri ZM, Kunicki TJ. The Modifier of hemostasis (Mh) locus on
chromosome 4 controls in vivo hemostasis of Gp6-/- mice. Blood. 2008 Feb
1;111(3):1266-73. Epub 2007 Nov 8. PubMed PMID: 17991808; PubMed Central PMCID:
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20: Labialle S, Yang L, Ruan X, Villemain A, Schmidt JV, Hernandez A, Wiltshire
T, Cermakian N, Naumova AK. Coordinated diurnal regulation of genes from the
Dlk1-Dio3 imprinted domain: implications for regulation of clusters of
non-paralogous genes. Hum Mol Genet. 2008 Jan 1;17(1):15-26. Epub 2007 Sep 27.
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21: McClurg P, Janes J, Wu C, Delano DL, Walker JR, Batalov S, Takahashi JS,
Shimomura K, Kohsaka A, Bass J, Wiltshire T, Su AI. Genomewide association
analysis in diverse inbred mice: power and population structure. Genetics. 2007
May;176(1):675-83. Epub 2007 Apr 3. PubMed PMID: 17409088; PubMed Central PMCID:
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22: Schwander M, Sczaniecka A, Grillet N, Bailey JS, Avenarius M, Najmabadi H,
Steffy BM, Federe GC, Lagler EA, Banan R, Hice R, Grabowski-Boase L, Keithley EM,
Ryan AF, Housley GD, Wiltshire T, Smith RJ, Tarantino LM, Müller U. A forward
genetics screen in mice identifies recessive deafness traits and reveals that
pejvakin is essential for outer hair cell function. J Neurosci. 2007 Feb
28;27(9):2163-75. PubMed PMID: 17329413.

23: Wiltshire T, Senft J, Wang Y, Konat GW, Wenger SL, Reed E, Wang W. BRCA1
contributes to cell cycle arrest and chemoresistance in response to the
anticancer agent irofulven. Mol Pharmacol. 2007 Apr;71(4):1051-60. Epub 2007 Jan
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24: Wang Y, Wiltshire T, Senft J, Wenger SL, Reed E, Wang W. Fanconi anemia D2
protein confers chemoresistance in response to the anticancer agent, irofulven.
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25: Walker JR, Wiltshire T. Databases of free expression. Mamm Genome. 2006
Dec;17(12):1141-6. Epub 2006 Dec 1. Review. PubMed PMID: 17143588.

26: Wang Y, Wiltshire T, Senft J, Reed E, Wang W. Irofulven induces
replication-dependent CHK2 activation related to p53 status. Biochem Pharmacol.
2007 Feb 15;73(4):469-80. Epub 2006 Oct 27. PubMed PMID: 17118344; PubMed Central
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27: Reijmers LG, Coats JK, Pletcher MT, Wiltshire T, Tarantino LM, Mayford M. A
mutant mouse with a highly specific contextual fear-conditioning deficit found in
an N-ethyl-N-nitrosourea (ENU) mutagenesis screen. Learn Mem. 2006
Mar-Apr;13(2):143-9. PubMed PMID: 16585790; PubMed Central PMCID: PMC1409825.

28: Delano DL, Montesinos MC, D'Eustachio P, Wiltshire T, Cronstein BN. An
interaction between genetic factors and gender determines the magnitude of the
inflammatory response in the mouse air pouch model of acute inflammation.
Inflammation. 2005 Feb;29(1):1-7. PubMed PMID: 16502340.

29: McClurg P, Pletcher MT, Wiltshire T, Su AI. Comparative analysis of haplotype
association mapping algorithms. BMC Bioinformatics. 2006 Feb 9;7:61. PubMed PMID:
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30: Moran JL, Bolton AD, Tran PV, Brown A, Dwyer ND, Manning DK, Bjork BC, Li C,
Montgomery K, Siepka SM, Vitaterna MH, Takahashi JS, Wiltshire T, Kwiatkowski DJ,
Kucherlapati R, Beier DR. Utilization of a whole genome SNP panel for efficient
genetic mapping in the mouse. Genome Res. 2006 Mar;16(3):436-40. Epub 2006 Feb 3.
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31: Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N,
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disrupts exogenous antigen presentation and signaling via Toll-like receptors 3,
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32: Fries S, Grosser T, Price TS, Lawson JA, Kapoor S, DeMarco S, Pletcher MT,
Wiltshire T, FitzGerald GA. Marked interindividual variability in the response to
selective inhibitors of cyclooxygenase-2. Gastroenterology. 2006
Jan;130(1):55-64. PubMed PMID: 16401468.

33: Ishimori N, Li R, Walsh KA, Korstanje R, Rollins JA, Petkov P, Pletcher MT,
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Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred
mice. J Bone Miner Res. 2006 Jan;21(1):105-12. Epub 2005 Sep 9. PubMed PMID:
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34: Delano DL, Montesinos MC, Desai A, Wilder T, Fernandez P, D'Eustachio P,
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effects of methotrexate in the air-pouch model of acute inflammation. Arthritis
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35: Owens SE, Broman KW, Wiltshire T, Elmore JB, Bradley KM, Smith JR,
Southard-Smith EM. Genome-wide linkage identifies novel modifier loci of
aganglionosis in the Sox10Dom model of Hirschsprung disease. Hum Mol Genet. 2005
Jun 1;14(11):1549-58. Epub 2005 Apr 20. PubMed PMID: 15843399.

36: Bystrykh L, Weersing E, Dontje B, Sutton S, Pletcher MT, Wiltshire T, Su AI,
Vellenga E, Wang J, Manly KF, Lu L, Chesler EJ, Alberts R, Jansen RC, Williams
RW, Cooke MP, de Haan G. Uncovering regulatory pathways that affect hematopoietic
stem cell function using 'genetical genomics'. Nat Genet. 2005 Mar;37(3):225-32.
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37: Sandberg ML, Sutton SE, Pletcher MT, Wiltshire T, Tarantino LM, Hogenesch JB,
Cooke MP. c-Myb and p300 regulate hematopoietic stem cell proliferation and
differentiation. Dev Cell. 2005 Feb;8(2):153-66. PubMed PMID: 15691758.

38: Pletcher MT, McClurg P, Batalov S, Su AI, Barnes SW, Lagler E, Korstanje R,
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39: Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD,
Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ,
Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD,
Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J,
Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G,
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Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G,
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Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman
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Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K,
Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi
Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K,
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LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams
RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F; Complex Trait Consortium. The
Collaborative Cross, a community resource for the genetic analysis of complex
traits. Nat Genet. 2004 Nov;36(11):1133-7. PubMed PMID: 15514660.

40: Pletcher M, Wiltshire T. Can we find the genes involved in complex traits?
Genome Biol. 2004;5(10):347. Epub 2004 Sep 22. PubMed PMID: 15461809; PubMed
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41: Wang J, Wiltshire T, Wang Y, Mikell C, Burks J, Cunningham C, Van Laar ES,
Waters SJ, Reed E, Wang W. ATM-dependent CHK2 activation induced by anticancer
agent, irofulven. J Biol Chem. 2004 Sep 17;279(38):39584-92. Epub 2004 Jul 20.
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42: Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, Zhang J, Soden R,
Hayakawa M, Kreiman G, Cooke MP, Walker JR, Hogenesch JB. A gene atlas of the
mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A. 2004
Apr 20;101(16):6062-7. Epub 2004 Apr 9. PubMed PMID: 15075390; PubMed Central
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43: Wen BG, Pletcher MT, Warashina M, Choe SH, Ziaee N, Wiltshire T, Sauer K,
Cooke MP. Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection
of T cells and modulates Erk activity. Proc Natl Acad Sci U S A. 2004 Apr
13;101(15):5604-9. Epub 2004 Apr 2. PubMed PMID: 15064401; PubMed Central PMCID:
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44: Panda S, Provencio I, Tu DC, Pires SS, Rollag MD, Castrucci AM, Pletcher MT,
Sato TK, Wiltshire T, Andahazy M, Kay SA, Van Gelder RN, Hogenesch JB. Melanopsin
is required for non-image-forming photic responses in blind mice. Science. 2003
Jul 25;301(5632):525-7. Epub 2003 Jun 26. PubMed PMID: 12829787.

45: Wiltshire T, Pletcher MT, Batalov S, Barnes SW, Tarantino LM, Cooke MP, Wu H,
Smylie K, Santrosyan A, Copeland NG, Jenkins NA, Kalush F, Mural RJ, Glynne RJ,
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46: Su AI, Cooke MP, Ching KA, Hakak Y, Walker JR, Wiltshire T, Orth AP, Vega RG,
Sapinoso LM, Moqrich A, Patapoutian A, Hampton GM, Schultz PG, Hogenesch JB.
Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U
S A. 2002 Apr 2;99(7):4465-70. Epub 2002 Mar 19. PubMed PMID: 11904358; PubMed
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47: Crabtree J, Wiltshire T, Brunk B, Zhao S, Schug J, Stoeckert CJ Jr, Bucan M.
High-resolution BAC-based map of the central portion of mouse chromosome 5.
Genome Res. 2001 Oct;11(10):1746-57. PubMed PMID: 11591652; PubMed Central PMCID:
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48: Pletcher MT, Wiltshire T, Cabin DE, Villanueva M, Reeves RH. Use of
comparative physical and sequence mapping to annotate mouse chromosome 16 and
human chromosome 21. Genomics. 2001 May 15;74(1):45-54. PubMed PMID: 11374901.

49: Tarantino LM, Feiner L, Alavizadeh A, Wiltshire T, Hurle B, Ornitz DM, Webber
AL, Raper J, Lengeling A, Rowe LB, Bucan M. A high-resolution radiation hybrid
map of the proximal portion of mouse chromosome 5. Genomics. 2000 May
15;66(1):55-64. PubMed PMID: 10843805.

50: Moreira ES, Wiltshire TJ, Faulkner G, Nilforoushan A, Vainzof M, Suzuki OT,
Valle G, Reeves R, Zatz M, Passos-Bueno MR, Jenne DE. Limb-girdle muscular
dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric
protein telethonin. Nat Genet. 2000 Feb;24(2):163-6. PubMed PMID: 10655062.

51: Wiltshire T, Pletcher M, Cole SE, Villanueva M, Birren B, Lehoczky J, Dewar
K, Reeves RH. Perfect conserved linkage across the entire mouse chromosome 10
region homologous to human chromosome 21. Genome Res. 1999 Dec;9(12):1214-22.
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52: Lengeling A, Wiltshire T, Otmani C, Bucán M. A sequence-ready BAC contig of
the GABAA receptor gene cluster Gabrg1-Gabra2-Gabrb1 on mouse chromosome 5.
Genome Res. 1999 Aug;9(8):732-8. PubMed PMID: 10447508; PubMed Central PMCID:
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53: Wallis DE, Roessler E, Hehr U, Nanni L, Wiltshire T, Richieri-Costa A,
Gillessen-Kaesbach G, Zackai EH, Rommens J, Muenke M. Mutations in the
homeodomain of the human SIX3 gene cause holoprosencephaly. Nat Genet. 1999
Jun;22(2):196-8. PubMed PMID: 10369266.

54: Cole SE, Wiltshire T, Rue EE, Morrow D, Hieter P, Brahe C, Fisher EM,
Katsanis N, Reeves RH. High-resolution comparative physical mapping of mouse
chromosome 10 in the region of homology with human chromosome 21. Mamm Genome.
1999 Mar;10(3):229-34. PubMed PMID: 10051316.

55: Cabin DE, McKee-Johnson JW, Matesic LE, Wiltshire T, Rue EE, Mjaatvedt AE,
Huo YK, Korenberg JR, Reeves RH. Physical and comparative mapping of distal mouse
chromosome 16. 5 p5. Genome Res. 1998 Sep;8(9):940-50. PubMed PMID: 9750193;
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56: Cole SE, Wiltshire T, Reeves RH. Physical mapping of the evolutionary
boundary between human chromosomes 21 and 22 on mouse chromosome 10. Genomics.
1998 May 15;50(1):109-11. PubMed PMID: 9628829.

57: Fang Y, Spisz TS, Wiltshire T, D'Costa NP, Bankman IN, Reeves RH, Hoh JH.
Solid-state DNA sizing by atomic force microscopy. Anal Chem. 1998 May
15;70(10):2123-9. PubMed PMID: 9608850.

58: Wiltshire T, Park C, Handel MA. Chromatin configuration during meiosis I
prophase of spermatogenesis. Mol Reprod Dev. 1998 Jan;49(1):70-80. PubMed PMID:
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59: Caldwell KA, Wiltshire T, Handel MA. A genetic strategy for differential
screening of meiotic germ-cell cDNA libraries. Mol Reprod Dev. 1996
Apr;43(4):403-13. PubMed PMID: 9052930.

60: Wiltshire T, Park C, Caldwell KA, Handel MA. Induced premature G2/M-phase
transition in pachytene spermatocytes includes events unique to meiosis. Dev
Biol. 1995 Jun;169(2):557-67. PubMed PMID: 7781899.

61: Handel MA, Caldwell KA, Wiltshire T. Culture of pachytene spermatocytes for
analysis of meiosis. Dev Genet. 1995;16(2):128-39. PubMed PMID: 7736663.