Pharmacogenomics is the study of how genes and genetic information influences the action of a drug.

Most drugs do not work effectively in all people and some also have undue side effects or toxicity. The variation people show in response to a drug, whether it is for efficacy or toxicity, can in part be explained by their own genetic makeups. Understanding the interactions of genes and drugs enables us to identify the most appropriate drug or dose for each individual.

At the UNC Center of Pharmacogenomics and Individualized Therapy, our goal is to use pharmacogenomic information to make drug and dose selection more personalized and precise, leading to improved efficacy and reduced side effects.


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