Pearce Lab
Pearce Lab
The Pearce lab utilizes numerous methods for conducting early drug and chemical probe discovery research. These techniques include development of biochemical and cell assays, high-throughput screening, DNA-encoded library technology, peptide phage display, and mechanistic/biophysical studies. Targets for these discovery campaigns include proteins involved in epigenetic regulation, signal transduction, and enzymatic modifications. Projects are typically collaborative efforts with labs across the UNC campus and span several therapeutic areas, with a particular focus on oncology targets.
Ken Pearce, PhD
Research Professor, Chemical Biology and Medicinal Chemistry
Director of Lead Discovery and Characterization
khpearce@unc.edu
Brian Hardy
Compound and Laboratory Manager
brianhardy@unc.edu
Jacob Larson
Graduate Student
jlarson7@email.unc.edu
Tina Leisner
Research Associate
tina_leisner@med.unc.edu
Jacqueline Norris-Drouin
Research Associate
jnorris@unc.edu
Devan Shell
Graduate Student
dshell19@live.unc.edu
Michael Stashko
Research Associate
mstashko@email.unc.edu