Skip to main content

Pearce Lab

The Pearce lab utilizes numerous methods for conducting early drug and chemical probe discovery research. These techniques include development of biochemical and cell assays, high-throughput screening, DNA-encoded library technology, peptide phage display, and mechanistic/biophysical studies. Targets for these discovery campaigns include proteins involved in epigenetic regulation, signal transduction, and enzymatic modifications. Projects are typically collaborative efforts with labs across the UNC campus and span several therapeutic areas, with a particular focus on oncology targets.


Ken Pearce, PhD

Research Professor, Chemical Biology and Medicinal Chemistry
Director of Lead Discovery and Characterization



Brian Hardy

Compound and Laboratory Manager




Jacob Larson

Graduate Student




Tina Leisner

Research Associate




Jacqueline Norris-Drouin

Research Associate





Devan Shell

Graduate Student




Michael Stashko

Research Associate