The Pattenden lab develops innovative techniques in chromatin-based therapeutic target discovery and cancer diagnostics. Our research program enables the discovery of novel molecular targets, pathways, and mechanisms. Our central strategy exploits tumor-specific changes in chromatin accessibility, a universal feature that is directly linked with transcriptional activation, DNA damage repair, replication, RNA processing, and nuclear organization.
Associate Professor, Chemical Biology and Medicinal Chemistry
Director of Applied Epigenetic Screening Technologies