The James lab is interested in modulating the activity of chromatin reader proteins with small-molecule ligands, specifically potent and selective chemical probes, in order to open new avenues of research in the field of chromatin biology and potentially translate to compounds of therapeutic value. They are also interested in applying novel probe-based techniques, such as affinity labeling technologies, to the study of epigenetic regulators.
Assistant Professor, Chemical Biology and Medicinal Chemistry
Director of Chemical Biology
Fred Eshelman Distinguished Professor
John Tabor, PhD
Mélanie Uguen, PhD