James/Frye Lab

The James lab is interested in modulating the activity of chromatin reader proteins with small-molecule ligands, specifically potent and selective chemical probes, in order to open new avenues of research in the field of chromatin biology and potentially translate to compounds of therapeutic value. They are also interested in applying novel probe-based techniques, such as affinity labeling technologies, to the study of epigenetic regulators.

Lindsey James, PhD

Assistant Professor, Chemical Biology and Medicinal Chemistry
Director of Chemical Biology
ingerman@email.unc.edu

Stephen Frye, PhD

Fred Eshelman Distinguished Professor
svfrye@email.unc.edu

Peter Buttery

Graduate Student
peterhb@live.unc.edu

Caroline Foley

Graduate Student
cfoley3@live.unc.edu

Rebecca Johnson

Graduate Student
rlj323@live.unc.edu

Lilyan Mather

Graduate Student
lmather@unc.edu

Juanita Sanchez

Graduate Student
jsanchex@unc.edu

John Tabor, PhD

Postdoc
jrtabor@email.unc.edu

Mélanie Uguen, PhD

Postdoc
muguen@email.unc.edu