James/Frye Lab

The James lab is interested in modulating the activity of chromatin reader proteins with small-molecule ligands, specifically potent and selective chemical probes, in order to open new avenues of research in the field of chromatin biology and potentially translate to compounds of therapeutic value. They are also interested in applying novel probe-based techniques, such as affinity labeling technologies, to the study of epigenetic regulators.

Lindsey James, PhD

Assistant Professor, Chemical Biology and Medicinal Chemistry
Director of Chemical Biology
ingerman@email.unc.edu

Stephen Frye, PhD

Fred Eshelman Distinguished Professor
Center Director
svfrye@email.unc.edu

Peter Buttery

Graduate Student
peterhb@live.unc.edu

Isabelle Engelberg

Graduate Student
iae17@email.unc.edu

Caroline Foley

Graduate Student
cfoley3@live.unc.edu

Kenneth Guzman-Rodriguez

Graduate Student
kennethb@live.unc.edu

Ronan Hanley, PhD

Postdoc
ronanh@email.unc.edu

Bryce Hart

Graduate Student
hartb1@live.unc.edu

Rebecca Johnson

Graduate Student
rlj323@live.unc.edu

John Tabor, PhD

Postdoc
jrtabor@email.unc.edu

Jarod Waybright

Postdoc
jarodw@email.unc.edu