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The James lab is interested in modulating the activity of chromatin reader proteins with small-molecule ligands, specifically potent and selective chemical probes, in order to open new avenues of research in the field of chromatin biology and potentially translate to compounds of therapeutic value. They are also interested in applying novel probe-based techniques, such as affinity labeling technologies, to the study of epigenetic regulators.

Lindsey James, PhD

Assistant Professor, Chemical Biology and Medicinal Chemistry
Director of Chemical Biology
ingerman@email.unc.edu
 
 
 

stephen_frye

Stephen Frye, PhD

Professor, Chemical Biology and Medicinal Chemistry
svfrye@email.unc.edu
 
 
 

Peter Buttery

Graduate Student
peterhb@live.unc.edu

 
 
 

Rebecca Johnson

Graduate Student
rlj323@live.unc.edu
 
 
 

Lilyan Mather

Graduate Student
lmather@unc.edu
 
 
 

Juanita Sanchez

Graduate Student
jsanchez@unc.edu

 
 
 

John Tabor, PhD

Postdoc
jrtabor@email.unc.edu

 
 
 

Mélanie Uguen, PhD

Postdoc
muguen@email.unc.edu