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Academic Programs Divisions Fellows PhD Pharmacotherapy and Experimental Therapeutics Students,
Grayson Mendenhall
January 7, 2013



Kyunghee Yang
Kyunghee Yang, MS

Kyunghee Yang, MS, a graduate student in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC Eshelman School of Pharmacy, has been awarded the Amgen Predoctoral Fellowship for the 2012-2013 academic year.

The fellowship is awarded annually to a third- or fourth-year student in the School’s PhD in pharmaceutical sciences program who has started a dissertation project in the field of drug metabolism or pharmacokinetics. It provides a full stipend, health insurance, and tuition for one academic year, as well as funds for research supplies. It also provides travel funds for the awardee to visit the PKDM Amgen site in Boston during the fall to meet with Amgen scientists and give a seminar presentation.

Yang entered the School’s PhD program in 2010. Before joining DPET, she received a BS and an MS in pharmacy from Seoul National University in South Korea and worked as a research specialist in the Department of Biopharmaceutical Sciences at the University of Illinois-Chicago. Kenan Distinguished Professor Kim Brouwer, PharmD, PhD, chair of DPET, is Yang’s major adviser.

She has authored twelve peer-reviewed manuscripts, including seven as first or co-first author, all focused on pharmacokinetics and drug metabolism. Her translational doctoral dissertation research project integrates pharmacokinetics, drug metabolism and transport, and toxicology using novel in vitro model systems with state-of-the-art mathematical modeling and simulation.

One of the aims of Yang’s dissertation is to develop physiologically based pharmacokinetic models of bile acid-drug interactions for incorporation into DILIsym™, a predictive systems pharmacology model of drug-induced liver injury. DILIsym™ is under development by the Institute for Drug Safety Sciences, a partnership between the Hamner Institutes for Health Sciences and the University of North Carolina at Chapel Hill.

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