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Chemical Biology and Medicinal Chemistry Divisions Grants and Awards,
Grayson Mendenhall
August 31, 2009



The American Chemical Society has announced that Michael T. Crimmins, senior associate dean for the natural sciences in the College of Arts and Sciences, has been awarded the 2010 Ernest Guenther Award for outstanding achievement in the chemistry of natural products. Crimmins holds a joint appointment in the UNC Eshelman School of Pharmacy as a professor in the Division of Medicinal Chemistry and Natural Products and is the Mary Ann Smith Professor of Chemistry in the Department of Chemistry.

The award recognizes and encourages outstanding achievements in the analysis, structure elucidation, and chemical synthesis of natural products. In selecting the nominee, special consideration is given to independence of thought and originality.

Crimmins’s research interests focus on the development of new synthetic methods and their application to the total synthesis of biologically active compounds, particularly natural products. A variety of new synthetic methods have been developed in his laboratories including stereoselective intramolecular photochemical cycloadditions, asymmetric aldol addition reactions of chlorotitanium enolates, tandem conjugate addition-cyclization reactions, radical fragmentation and rearrangement reactions, methods for spiroketal synthesis, and ring closing metathesis of medium rings. His research group has completed the total synthesis of more than thirty-five architecturally complex natural products.

He is a previous chair of the North Carolina section of the American Chemical Society and received its Arthur C. Cope Scholar Award in 2001 and the Charles Holmes Herty Medal in 2004. With more than 154,000 members, the American Chemical Society is the world’s largest scientific society.

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