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This fellowship is part of the DPET fellowship program.

  • Length: Two to three years
  • Accreditation: American College of Clinical Pharmacy

This fellowship program prepares highly motivated individuals to become independent researchers and academic faculty members in anti-infective clinical pharmacology. The program helps fellows develop the research expertise they need to compete for and secure research funding. Fellows will gain experience in all areas of translational research, ranging from grant writing to manuscript submission, and are expected to present research findings at scientific meetings. Research activities will focus on investigator-initiated programs and collaborative research programs within UNC’s Center for AIDS Research.

Residency experience is strongly preferred. Appointment includes a UNC benefits package and a competitive stipend.

Program Components

  • PK/PD investigations: The fellow will work within existing Center for AIDS Research collaborations to assist in the design, conduct and analysis of preclinical and clinical PK studies, and harness existing datasets to perform computational modeling and simulation for novel HIV therapeutics.
  • Laboratory investigations: The fellow may use in vitro model systems in addition to analytical chemistry and molecular biology techniques to advance training in translational research.
  • Clinical investigations: The fellow will learn about conduct of clinical investigations for both healthy-volunteer and patient populations and may participate in clinical studies as study enrollment allows.
  • Clinical service: This fellowship is primarily focused on developing proficiency in translational research, but limited clinical service is available through participation in the Laboratory’s CAP/CLIA accredited Therapeutic Drug Monitoring (TDM) program.
  • Teaching: The fellowship will provide opportunities to develop student-teaching skills in both didactic and small, problem-based group environments.
  • Scientific meetings: The fellow will attend at least two annual scientific meetings such as ICAAC, CROI, or ASCPT. Attendance at additional meetings will be supported as abstracts are accepted for presentation. The fellow will attend at least two annual scientific meetings such as ICAAC, CROI, or ASCPT. Attendance at additional meetings will be supported as abstracts are accepted for presentation.

Available Courses

  • Ethical Dilemmas in Research
  • Experimental Design Considerations in Clinical Research
  • Principles of Statistical Inference
  • Research seminar series
  • Introduction to Applied Pharmacogenomics
  • Advanced Pharmacokinetics and Pharmacodynamics
  • Drug Metabolism

Program Director

Angela Kashuba, BScPhm, PharmD, DABCP, FCP
Dean, UNC Eshelman School of Pharmacy
John A and Margaret P McNeill Sr. Distinguished Professor
Director, Clinical Pharmacology and Analytical Chemistry Core, UNC Center for AIDS Research
Adjunct Professor of Medicine, UNC School of Medicine, Division of Infectious Diseases

Kashuba’s research interests include preclinical and clinical antiretroviral pharmacology, HIV therapy for treatment, prevention, and cure, and PK/PD relationships. She is director of the UNC Center for AIDS Research Clinical Pharmacology and Analytical Chemistry Core, and Director of the Pharmacology Core for the UNC Delaney CARE Collaboratory for HIV Eradication. She also co-directs the UNC-Duke-Hamner Clinical Pharmacology T32 Fellowship program.  She is currently a member of the Advisory Committee for the NIH Office of Research on Women’s Health, the Organizing Committee for the International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy, and the Organizing Committee for the International HIV and Women Workshop.

Additional Research Infrastructure at UNC-Chapel Hill

UNC Center for AIDS Research
Provides infrastructure to support investigation of HIV/AIDS using clinical and behavioral research, investigation into HIV biology and pathogenesis at the molecular level, and educational outreach.

UNC AIDS Clinical Trials Unit
Conducts and develops research into HIV infection and its associated opportunistic infections and provides access to promising clinical protocols to HIV patients.

Application Requirements:

Contact for Program Information

Angela D. M. Kashuba, Pharm.D.