Certara Pharmacokinetics/Pharmacodynamics Fellowship

This fellowship is sponsored in collaboration with Certara and is part of the DPET fellowship program.

• Length: Two years

The UNC Eshelman School of Pharmacy and Certara offers a two-year postdoctoral fellowship in pharmacokinetics/pharmacodynamics (PK/PD).

Requirements: Minimum of a PharmD, MD, or PhD with knowledge of PK/PD analyses. Excellent communication skills and ability to work independently as well as a member of an interdisciplinary team are essential. Interested applicants can apply through this web site: http://pharmacydpetfellowships.web.unc.edu/

Program Description

First Year

Fellows will participate in clinical pharmacology and drug-transport and metabolism studies with faculty at the UNC Eshelman School of Pharmacy. Each fellow will design, initiate, conduct, and analyze various research projects as part of the learning experience.

Fellows will also enroll in advanced courses in PK/PD and clinical research methods and may attend additional courses such as biostatistics, advanced therapeutics, drug metabolism, and molecular biology.

Second Year

Fellows will work at Certara’s Raleigh, NC office, with an option to focus on either pharmacometrics or clinical pharmacology.   For pharmacometrics, fellows be involved in the application of state-of-the-art quantitative methodologies to drug development, such as conventional and population PK and PD analyses, exposure-response, and clinical trial simulations. They will use advanced techniques as they participate in modeling and simulation efforts for quantitative decision making. For clinical pharmacology, fellows may review, design and/or analyze a variety of clinical pharmacology studies, including first-in-human, proof-of-concept, drug-drug interaction, QT, end-organ dysfunction studies.

At the completion of the Fellowship, the post-doctoral fellow will be able to:

• Describe the importance of clinical research in drug development;
• Describe the nature and relevance of clinical data evaluations relative to drug development;
• Design and implement studies to examine drug absorption, drug disposition, pharmacodynamic endpoints and drug interactions in healthy human volunteers or diseased patient populations;
• Understand foundational concepts related to population PK/PD and physiologically-based PK modeling and simulation techniques;
• Understand important considerations in clinical trial design and the conduct of clinical investigations in specific patient populations (e.g., pediatrics);
• Perform PK/PD and statistical data analysis using relevant software packages;
• Prepare manuscripts, seminars and other scholarly vehicles for communication of scientific results.

The fellowship provides a competitive stipend, health insurance, and professional travel.

About Certara

Certara optimizes R&D productivity, commercial value and patient outcomes through its unique portfolio of model-informed drug development, regulatory science, and market access solutions. In fact, 90+% of all novel drugs approved by the US FDA in the past six years were supported by Certara software or services. Its clients include 1,600 global biopharmaceutical companies, leading academic institutions, and key regulatory agencies across 60 countries. For more information, visit www.certara.com.

To Apply

Visit http://pharmacydpetfellowships.web.unc.edu/  for instructions on submitting an application.

Application Opens: September 1, 2022

Early Application Deadline: October 31, 2022

Final Application Deadline:  November 21, 2022

Contact for Program Information: