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Experienced faculty mentors are chosen based on their research productivity in at least one of four focus areas that form the core of this training program: Drug Disposition and Action; Quantitative Pharmacology/Pharmacometrics & Clinical Trial Design; Individualized Therapy; Drug-induced Organ Toxicity.

 

Affiliation:Assistant Professor of Medicine, Division of Infectious Diseases, UNC School of Medicine

Research Interests: HIV latency


Affiliation: Distinguished Professor, Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy and Curriculum in Toxicology, UNC School of Medicine

Research Interests: Hepatic drug transport (mechanisms, model systems, clinical probes); clinical DDIs and disease state alterations in drug disposition/biliary clearance; drug-induced hepatotoxicity


Affiliation: Professor, Division of Hematology & Oncology, School of Medicine; Lineberger Comprehensive Cancer Center

Research Interests: Breast Cancer; Phase I trials, focus on the elderly


Affiliation: Professor, Division of Gastroenterology and Hepatology, UNC School of Medicine; Director, UNC Liver Center

Research Interests: Novel treatments for viral hepatitis B and C, Phase 2, 3 clinical trials; drug-induced liver injury


Affiliation: Associate Professor of Neurology, UNC School of Medicine

Research Interests: Neurobiology of cerebellar development and medulloblastoma


Affiliation: Associate Professor, Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy

Research Interests: Pharmacokinetics/pharmacodynamics of drugs, including the application of pharmacometrics to inform individualized drug dosing and clinical trial design


Affiliation: Associate Professor, Division of Infectious Diseases, UNC School of Medicine

Research Interests: Malaria drug resistance, diversity & population evolution


Affiliation: Distinguished Professor, Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy; Director, Clinical Pharmacology and Analytical Chemistry Core, UNC Center for AIDS Research; Director, Pharmacology Core, UNC Collaboratory of AIDS Researchers for Eradication; Division of Infectious Diseases, UNC School of Medicine

Research Interests: Clinical pharmacology of antiretroviral agents in HIV infection; preventing HIV transmission; understanding/predicting drug-drug interactions and adverse events; sex and ethnicity in drug disposition


Affiliation: Professor of Pediatrics, Division of Neonatal-Perinatal Medicine, UNC School of Medicine

Research Interests: Epidemiology; clinical trials; pharmacology


Affiliation: Professor, Dept. of Pediatrics, School of Medicine; Dept. of Microbiology & Immunology, School of Medicine; Curriculum in Toxicology, UNC School of Medicine; Dept. of Epidemiology, School of Public Health

Research Interests: Translational and clinical research in environmental lung disease, particularly asthma;  novel treatments for asthma


Affiliation: Professor, Division of Hematology & Oncology, UNC School of Medicine; Dept. of Microbiology & Immunology, School of Medicine

Research Interests: Migration of dendritic cells and subpopulations of T lymphocytes during graft-versus-host disease (GVHD) after allogeneic stem cell transplantation and as a consequence of induction of an immune response to tumors using vaccine therapy


Affiliation: Associate Professor, Division of Infectious Diseases, UNC School of Medicine

Research Interests: Antimicrobial resistance


Affiliation: Howard Q. Ferguson Distinguished Professor, Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy and Director, UNC Institute for Drug Safety Sciences

Research Interests: Mechanisms underlying idiosyncratic hepatotoxicity; inter-individual differences in the pharmacokinetics of drugs and other chemicals (xenobiotics); Quantitative Systems Toxicology


Affiliation: Associate Professor, Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy; Lineberger Comprehensive Cancer Center

Research Interests: Application of pharmacokinetic, pharmacodynamic, and pharmacogenetic principles in the optimization of the chemotherapeutic treatment of cancer


Affiliation: Professor of Medicine, Cardiology, and Director of Cardiovascular Research, Duke Clinical Research Institute

Research Interests: Therapeutics for acute coronary syndromes, chronic coronary artery disease, and cardiac surgery and novel methodological approaches to clinical trials


Affiliation: Professor of Pediatric Infectious Diseases; Associate Director of the Duke Clinical Research Institute

Research Interests: Neonatal antimicrobial pharmacokinetic and therapeutic drug trials; antifungal pharmacokinetics/pharmacodynamics


Affiliation: Professor of Pediatrics, Duke University School of Medicine

Research Interests: Pharmacokinetics and pharmacodynamics of drugs in children, minimal risk methods, Phase 1 studies in humans


Affiliation: Professor, Division of Infectious Diseases, Department of Medicine; Department of Molecular Genetics and Microbiology, Duke University School of Medicine

Research Interests: Pathogenesis of bacterial infections; infections due to resistant organisms


Affiliation: Associate Professor of Neurology, Duke University School of Medicine

Research Interests: Phase 1 studies in humans; neuro-therapeutics


Affiliation: Associate Professor of Pediatrics, Duke University School of Medicine and Member of Duke Clinical Research Institute

Research Interests:Applications of pharmacokinetic/ pharmacodynamic modeling and simulation to promote safe and effective drug use in critically ill children


Affiliation: Associate Professor, Obstetrics/Gynecology, Division Chief, Maternal Fetal Medicine, Department of Obstetrics and Gynecology, and Vice Chair, Obstetrics, Duke University

Research Interests: Infectious diseases in pregnancy


Affiliation: Professor & Division Chief, Pediatric Cardiology, Duke University School of Medicine, and Member of the Duke Clinical Research Institute

Research Interests: Pediatric cardiovascular diseases and treatment including Phase I and multi-center trials


Affiliation: Associate Professor of Cardiology, Duke University School of Medicine and Member of Duke Clinical Research Institute

Research Interests: Co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research


Affiliation: Professor, Department of Medicine, Division of Geriatrics, Duke University School of Medicine

Research Interests: Pharmacotherapy and drug toxicity in the elderly; vaccine trials in the elderly


Affiliation: Professor, Department of Pediatrics, Division of Neonatology, Duke University School of Medicine

Research Interests: Nosocomial infections; neonatal candidiasis; neonatal pharmacology; drug safety


Affiliation: Professor, Department of Pediatrics, Duke University School of Medicine

Research Interests: Vaccine trials


Affiliation: Professor, Department of Anesthesiology, Duke University School of Medicine

Research Interests: Nutritional therapy

Junior Program Faculty

Affiliation: Assistant Professor, Division of Pharmacotherapy and Experimental Therapeutics in the UNC Eshelman School of Pharmacy

Research Interests: Pharmacokinetics/pharmacodynamics, and systems pharmacology/biology, Integrating antibody pharmacokinetics/pharmacodynamics and host system to optimize antibody-based therapies


Affiliation: Assistant Professor, Division of Pharmacotherapy and Experimental Therapeutics in the UNC Eshelman School of Pharmacy

Research Interests: Anticancer Pharmacotherapy


Affiliation: Associate Professor, Division of Pharmacotherapy and Experimental Therapeutics in the UNC Eshelman School of Pharmacy

Research Interests: Antiretroviral clinical pharmacology, including pharmacokinetics/pharmacodynamics, drug-drug interactions, and intracellular disposition of the nucleoside reverse transcriptase inhibitors


Affiliation: Professor, Division of Pharmacotherapy and Experimental Therapeutics in the UNC Eshelman School of Pharmacy

Research Interests: Metabolism of drugs and eicosanoids by the cytochromes P450 enzyme system; cardiovascular and metabolic disease


Affiliation: Assistant Professor, Division of Pharmacotherapy and Experimental Therapeutics in the UNC Eshelman School of Pharmacy

Research Interests: Quantitative systems pharmacology, complex host-pathogen interactions and perturbations imposed by therapeutic interventions

Affiliation: Assistant Professor of Pediatrics, Assistant Professor of Medicine, Member of the Duke Clinical Research Institute, Duke University School of Medicine

Research Interests: Clinical trials and precision medicine through population pharmacokinetic/pharmacodynamic modeling


Affiliation: Assistant Professor of Pediatrics and Member of the Duke Clinical Research Institute, Duke University School of Medicine

Research Interests: Treatment of infections in the neonatal intensive care unit, and improving the safety and efficacy of drugs in premature infants


Affiliation: Associate Professor of Pediatrics, Associate of the Duke Initiative for Science & Society, Member of the Duke Clinical Research Institute, Duke University School of Medicine

Research Interests: Clinical research including outcomes, drug and device trials, short and long term safety and efficacy of interventions and hemodynamic effects of interventions.


Affiliation: Associate Professor of Pediatrics, Duke University School of Medicine and Member of the Duke Clinical Research Institute, Duke University School of Medicine

Research Interests: Pediatric pharmacotherapy; pharmacokinetics/pharmacodynamics; pharmacoepidemiology, drug safety in pediatric critical illness