Karl M Koshlap
Research Associate, Division of Chemical Biology and Medicinal Chemistry
SB205E Marsico Hall, , CB# 7363, Chapel Hill, NC, 27599
Karl Koshlap came to the UNC Eshelman School of Pharmacy in 2004 to manage the NMR Core Facility. The spectrometers in the laboratory are used to study molecular structure and dynamics, and are used both by chemists studying small molecules—drugs or natural products, for example—and those doing biomolecular NMR, e.g., studying protein dynamics or oligosaccharide structure. Before coming to UNC, Koshlap managed the Biomolecular NMR Laboratory in the Department of Biochemistry and Biophysics at Texas A&M University.
Koshlap received his PhD from the Department of Chemistry and Biochemistry at UCLA. His adviser was Juli Feigon, PhD, in whose lab he used NMR to study unusual DNA structures. He then did a postdoctoral fellowship at North Carolina State University in the laboratory of Paul Agris, PhD, where he again used NMR, this time to study modified RNAs.