Juliane Nguyen, Ph.D.
Associate Professor, Division of Pharmacoengineering and Molecular Pharmaceutics
4205 Marsico Hall, , , Chapel Hill, NC, 27599, , 125 Mason Farm Road, , , Chapel Hill, NC, 27599
Dr. Juliane Nguyen is an Associate Professor in the Division of Pharmacoengineering and Molecular Pharmaceutics. Her translational research program focuses on developing the next generation of safe and effective biotherapeutics for life-threatening diseases such as cancer and myocardial infarction.
Her research has led to the discovery of novel biomaterials that allow unprecedented loading of stem-cell derived exosomes with therapeutic cargoes including nucleic acids, paving the way for cell-free therapeutics in many diseases including cardiac regeneration after myocardial infarction. Her lab recently developed immunomodulatory protein-based agents capable of reprogramming tumor-associated macrophages and T cells to suppress the growth of triple-negative breast cancer and other aggressive cancers.
Dr. Nguyen’s work has been recognized with numerous awards, including the CMBE Young Innovator Award (2019), the AAPS Emerging Leader Award (2019), the NYSTAR Faculty Award (2019), the National Science Foundation CAREER Award (2018), the Pioneering Pharmaceutical Sciences by Emerging Investigators Award (2018), and the University at Buffalo – Exceptional Scholar Young Investigator Award (2017).
Dr. Nguyen is committed to educating and training the next generation of pharmaceutical and biomaterials science leaders. She received her PharmD and PhD from the Philipps-University of Marburg (Germany) and she completed her postdoctoral training at the University of California, San Francisco, where she trained with Dr. Francis Szoka. Prior to joining the University of North Carolina at Chapel Hill in 2019, she was an Assistant Professor at the University at Buffalo (2013-2019).
- CAREER: Active-Loadable Poresomes for the Cytoplasmic Delivery of Membrane-Impermeable Compounds
- RNA EXO-Codes: A novel way to reprogram pathological exosomes