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Juliane Nguyen

Associate Professor

Juliane Nguyen, Ph.D.

Vice Chair, Division of Pharmacoengineering and Molecular Pharmaceutics

Associate Professor, Division of Pharmacoengineering and Molecular Pharmaceutics

Associate Professor, Department of Biomedical Engineering


Juliane-Nguyen

PHONE
(919) 962-4538
EMAIL
julianen@email.unc.edu
ADDRESS
4205 Marsico Hall, 125 Mason Farm Road, , Chapel Hill, NC, 27599
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Dr. Juliane Nguyen is an Associate Professor in the Division of Pharmacoengineering and Molecular Pharmaceutics. Her translational research program focuses on developing the next generation of safe and effective biotherapeutics for life-threatening diseases such as cancer and myocardial infarction.

Her research has led to the discovery of novel biomaterials that allow unprecedented loading of stem-cell derived exosomes with therapeutic cargoes including nucleic acids, paving the way for cell-free therapeutics in many diseases including cardiac regeneration after myocardial infarction. Her lab recently developed immunomodulatory protein-based agents capable of reprogramming tumor-associated macrophages and T cells to suppress the growth of triple-negative breast cancer and other aggressive cancers.

Dr. Nguyen’s work has been recognized with numerous awards, including the CMBE Young Innovator Award (2019), the AAPS Emerging Leader Award (2019), the NYSTAR Faculty Award (2019), the National Science Foundation CAREER Award (2018), the Pioneering Pharmaceutical Sciences by Emerging Investigators Award (2018), and the University at Buffalo – Exceptional Scholar Young Investigator Award (2017).

Dr. Nguyen is committed to educating and training the next generation of pharmaceutical and biomaterials science leaders. She received her PharmD and PhD from the Philipps-University of Marburg (Germany) and she completed her postdoctoral training at the University of California, San Francisco, where she trained with Dr. Francis Szoka. Prior to joining the University of North Carolina at Chapel Hill in 2019, she was an Assistant Professor at the University at Buffalo (2013-2019).

Education, Certification and Licensure

  • 2009 – 2013: Post-doc in Bioengineering at Univerisity of California San Francisco
  • 2005 – 2009: Ph.D. in Pharmaceutical Sciences at Philipps-University Marburg (Germany)
  • 1999 – 2005: Board Certified Pharmacist (certified in Germany) at Philips-University Marburg (Germany)

Google Scholar

Lab Website

Twitter @JulieNguyenLab

ORCID iD: 0000-0002-8578-7396

Current Projects

  • Polarizing Macrophages to Tumor Suppressors by Blocking Multiple CCR2 Chemokine Receptor Epitopes
  • Antibody Fragments as Biochemical Tools to Interrogate CD9 Function in Inflammatory Diseases
  • CAREER: Active-Loadable Poresomes for the Cytoplasmic Delivery of Membrane-Impermeable Compounds
  • RNA EXO-Codes: A novel way to reprogram pathological exosomes
  • Self-replicating RNA-nanoplexes for programming monocytes to regenerate the heart

Honors and Awards

2021-25 Standing Member – NIH Gene and Drug Delivery Study Section
2019 AAPS Emerging Leader Award – American Association of Pharmaceutical Scientists
CMBE Young Innovator Award – Biomedical Engineering Society (BMES)
NY-STAR Faculty Award
2018 NSF CAREER Award
Pioneering Pharmaceutical Science by Emerging Investigators Award
Award for late-breaking talk at the Gordon Research Conference on Drug Carriers in Biology and Medicine
2017 University at Buffalo Exceptional Scholar – Young Investigator Award
2011 Biomedical Breakthrough Award at UCSF
2011-13 German Research Foundation Fellowship (DFG) Award
2007 Controlled Release Society Travel Award
2005 German PharmD Fellowship Award