Aaron Anselmo, Ph.D.
Assistant Professor, Division of Pharmacoengineering and Molecular Pharmaceutics
Marsico Hall, , , Chapel Hill, NC, 27599, , 125 Mason Farm Road, , , Chapel Hill, NC, 27599
Aaron C. Anselmo, Ph.D. joined the UNC Eshelman School of Pharmacy in 2017 as an assistant professor in the Division of Pharmacoengineering and Molecular Pharmaceutics. Anselmo, who has authored over 30 peer-reviewed publications, received his B.S. degree in Chemical Engineering from Rensselaer Polytechnic Institute and then earned his Ph.D. in Chemical Engineering at the University of California, Santa Barbara.
The Anselmo lab focuses on understanding microbe-material-host tissue interactions to develop: (i) formulations for the improved delivery of therapeutic microbes, (ii) materials-based in vitro culture approaches to enable the co-culture of microbial ecologies alongside mammalian cells, and (iii) targeted approaches for the delivery of therapeutic microbes.
Additionally, the Anselmo lab is interested in understanding how the physicochemical properties of nanoparticles influences their biological fate and function. Anselmo has developed a number of improved nanoparticle formulations based on modulating nanoparticle size, shape, and elasticity. Building on this, Anselmo has shown that it is possible to transfer the innate delivery abilities of our own cells to nanoparticles by either attaching nanoparticles to the cell’s surface (cellular hitchhiking) or by mimicking our cell’s unique physicochemical properties (synthetic cells).
Sustained Delivery of Microbes to Treat Ulerative Colitis
2010, B.S., Chemical Engineering, Rensselaer Polytechnic Institute
2015, Ph.D., Chemical Engineering, University of California, Santa Barbara
2017, Postdoctoral studies, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology