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McLeod Joins School as Eshelman Professor

July 19, 2006

Howard McLeod, PharmD, formerly of Washington University in St. Louis, has been appointed the Fred Eshelman Distinguished Professor in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC School of Pharmacy. He is also the director of the new UNC Institute for Pharmacogenomics and Individualized Therapy and a member of the UNC Lineberger Comprehensive Cancer Center. “Dr. McLeod is one of the pioneers in the field of cancer pharmacogenomics and we are extremely pleased that he has decided to join the faculty,” said Kim Brouwer, PharmD, chair of the division. Richard Goldberg, MD, associate director of UNC Lineberger, said, … Read more


Ghibellini Awarded Travel Grant

July 13, 2006

Giulia Ghibellini, a graduate student in the Division of Pharmacotherapy and Experimental Therapeutics, has been awarded a travel grant to attend the 14th North American International Society for the Study of Xenobiotics meeting. Ghibellini’s abstract, “In Vitro Characterization and Pharmacokinetic Modeling of Tc-99m Mebrofenin Hepatobiliary Disposition in Humans” was selected as a finalist in the postdoctoral category in the ISSX award program.


Kashuba Awarded $1.7 Million to Study Drug-Interaction Potential of New HIV Protease Inhibitor

June 19, 2006

Angela D. M. Kashuba, PharmD, has been awarded a $1.7 million contract from Boehringer Ingelheim to study the drug-interaction potential of tipranavir, a new HIV protease inhibitor. Protease is an enzyme that HIV needs in order to make new viruses. When protease is blocked, HIV makes copies of itself that can’t infect new cells. According to Kashuba, many individual drug-drug interaction studies have demonstrated tipranavir’s high interaction potential. Kashuba’s novel phenotyping approach will help in understanding the basis for these interactions and will form the groundwork for further exploration of potentially important drug interactions. The title of Kashuba’s project is “Evaluating the Effects of Tipranavir (with Ritonavir) … Read more


Hansen Receives NIH Career Development Award

June 14, 2006

Richard Hansen, PhD, was named a Clinical Research Scholar under the UNC Multidisciplinary Clinical Research Career Development Program. This award is part of the National Institutes of Health Roadmap Initiative and will provide salary and research funding over five years to support Hansen’s work in the multidisciplinary management of depression in primary care. Hansen’s project “The Quality of Antidepressant Use in Primary Care” focuses on understanding and improving adherence to antidepressants in non-psychiatric settings. The UNC MCRCDP is designed to re-engineer the clinical research enterprise by training new clinical research leaders, which is a key component of the NIH Roadmap. Eugene … Read more


Chen Presents Poster at ISPOR Meeting

June 14, 2006

Shih-Yin (Sharon) Chen, a second-year doctoral student in the Division of Pharmaceutical Outcomes and Policy, presented her poster “Cost-utility Analysis of Tegaserod for the Treatement of Irritable Bowel Syndrome” at the 11th annual ISPOR meeting in May. Chen’s poster was recognized as “high impact” and was among the top 25 percent eligible for poster awards.


Kohn Awarded $1.3 Million to Study Treatment of Neurological Disorders

June 14, 2006

Harold Kohn, PhD, Kenan Professor in the UNC School of Pharmacy’s Division of Medicinal Chemistry and Natural Products, has been awarded a $1.3 million grant from the National Institute of Neurological Disorders and Stroke. The title of Kohn’s project is “Novel Methods to Identify Targets of the Neurological Agent (R)-Lacosamide.” The NIH-funded study is a joint project between the Kohn and Rihe Liu Laboratories. Liu is an assistant professor at the School. According to Kohn’s proposal, epilepsy and neuropathic pain are major neurological disorders that can be treated with a number of different seizure medications. “Even with the use of these medications, many … Read more


Xiao Appointed Fred Eshelman Distinguished Professor of Gene Therapy

June 12, 2006

Xiao Xiao, PhD, has been appointed Fred Eshelman Distinguished Professor of Gene Therapy in the Division of Molecular Therapeutics in the UNC School of Pharmacy. Before coming to the School, Xiao was an associate professor at the University of Pittsburgh School of Medicine where he held several joint appointments. He was also an adjunct professor at Huazhong Science and Technology University Tongji Medical College in Wuhan, China, and a guest professor at Fudan University Shanghai Medical College in Shanghai, China. In 1982 Xiao received a BS in pharmaceutical chemistry from the Shanghai Medical University School of Pharmacy. He received a MS … Read more


Researcher Daniel Cline Receives NIH Kirschstein Award

June 7, 2006

Daniel Cline, a postdoctoral research scientist in the Singleton Lab at the UNC School of Pharmacy, has received the Ruth L. Kirschstein National Research Service Award from the National Institutes of Health. The Kirschstein NRSAs are individual postdoctoral fellowships given to promising applicants with the potential to become productive, independent investigators in fields related to the mission of the NIH constituent institutes and centers. “This post-doctoral appointment provides the opportunity to broaden my experience in molecular biology, with particular emphasis on drug design and delivery,” Cline says. “My overall goal is to become a well-rounded medicinal chemist and to develop useful therapies for treatment of infectious … Read more


Maciejewski Appointed Associate Professor

June 2, 2006

Matthew Maciejewski, PhD, has been appointed associate professor in the Division of Pharmaceutical Outcomes and Policy. Maciejewski comes to the School of Pharmacy from the University of Washington in Seattle, where he was an associate professor at the School of Public Health and Community Medicine. Maciejewski received a BS in Foreign Service from Georgetown University in 1991 and a PhD in health services and research policy from the University of Minnesota in 1998. From 1991-1993 he worked as a research assistant for the Board of Governors of the Federal Reserve System in Washington D.C. From 1993-1998 Maciejewski was a research … Read more


Roth Receives NIH Career Development Award

May 25, 2006

Mary Roth, PharmD, MHS, assistant professor in the Division of Pharmaceutical Outcomes and Policy, was awarded a Mentored Patient-Oriented Research Career Development Award from the National Institute on Aging. Roth will receive $699,170 over five years to support her project “Improving the Quality of Medication Use in Older Adults.” The goal of the project is to design, implement, and evaluate a medication management program to improve the quality of medication use for older adults. The purpose of the NIH Mentored Patient-Oriented Research Career Development Award is to support the career development of investigators who have made a commitment to focus their research endeavors … Read more