Category: Center for Nanotechnology in Drug Delivery
UNC Nanomedicine Researchers Uncover High Potential for Low-Frequency Magnetic Fields
November 16, 2012A team of researchers led by scientists at the UNC Eshelman School of Pharmacy has discovered effects of low-frequency magnetic fields that might pave the way for new approaches to designing remote-control nanomedicines. In a paper published online October 18 in the journal Angewandte Chemie, the researchers describe an experiment in which they attached an enzyme to magnetic nanoparticles, exposed them to nonheating, low-frequency magnetic fields, and observed the resulting changes in the enzymes’ structure, conformation, and catalytic activity, which were different from changes induced by heating up the nanoparticles. The results demonstrated for the first time magneto-mechanical effects triggered … Read more
Kabanov Leads Nanomedicine Team from Nebraska to UNC Pharmacy
October 4, 2012A group of twenty researchers from the University of Nebraska moved halfway across the country this summer to the University of North Carolina at Chapel Hill to join the Center for Nanotechnology and Drug Delivery in the UNC Eshelman School of Pharmacy. Led by Alexander “Sasha” Kabanov, PhD, who will direct the center, the group comprises Elena Batrakova, PhD, and a team of eighteen that includes three research faculty, postdoctoral fellows, research managers, and technicians, along with five graduate students who transferred to Carolina to continue their education. Kabanov’s group brings to UNC a research program that will receive more … Read more
Discovery by Jin, Roth Could Lead to Better Schizophrenia Drugs
October 24, 2011Scientists led by researchers at the UNC Eshelman School of Pharmacy have discovered three first-in-class chemical compounds that could lead to safer, more effective medications for schizophrenia and related disorders. Schizophrenia is typically treated with antipsychotic medications, but the medications do not adequately treat a high percentage of patients. The drugs don’t address the negative and cognitive symptoms of schizophrenia, and all current antipsychotics can lead to serious side effects such as cardiovascular conditions and weight gain with chronic use. The new compounds, which UNC has patented, will help address these problems by enabling researchers to better study which key … Read more
Mumper Appointed as Executive Associate Dean
June 8, 2010Russell Mumper, PhD, has assumed the role of the executive associate dean for academics at the UNC Eshelman School of Pharmacy effective June 1. Mumper is the John A. McNeill Distinguished Professor in the Division of Molecular Pharmaceutics and director of the School’s Center for Nanotechnology in Drug Delivery. In this new position, he succeeds Gary Pollack, PhD, who has been named as the dean of the Washington State University College of Pharmacy. Mumper’s experience and success in both industry and in academia made him a natural for the job, says Dean Robert Blouin. “Russ has published more than 200 … Read more
Mumper Named AAPS Fellow
November 9, 2009The American Association of Pharmaceutical Scientists has named Russell Mumper, PhD, one of its 2009 fellows. The honor recognizes individuals who have made sustained, remarkable scholarly and research contributions to the pharmaceutical sciences, such as original articles, scientific presentations at AAPS Annual Meetings, and patents. Mumper is the John A. McNeill Distinguished Professor in the Division of Molecular Pharmaceutics and director of the School’s Center for Nanotechnology in Drug Delivery. His research on the creation of drug-, gene-, and vaccine-delivery systems has led to several first-in-human studies in the past twenty years. His current research focuses on nanoparticle-based systems to … Read more
Mumper Study: Nanocapsules Can Overcome Chemotherapy Resistance
May 21, 2009One of the most challenging situations that oncologists face is when chemotherapy fails to slow down or stop the growth of cancer. This phenomenon, called multi-drug resistance, is the result of several simultaneous biochemical processes that scientists do not fully understand. New research led by pharmaceutical scientist Russell Mumper, PhD, director of the UNC Center for Nanotechnology in Drug Delivery and member of the UNC Lineberger Comprehensive Cancer Center, uses nanotechnology to overcome multi-drug resistance. Mumper’s team used an innovative formulation of lipid nanocapsules loaded with the anticancer drugs doxorubicin or paclitaxel to destroy cancer cells both in laboratory-based experiments … Read more
Photos: Fourth Annual Chapel Hill Drug Conference
May 19, 2009The UNC Eshelman School of Pharmacy hosted the Fourth Annual Chapel Hill Drug Conference on May 13-14. The conference focused on identifying the opportunities and challenges in bringing cutting-edge nanotechnology from discovery through preclinical evaluation and into human clinical studies and onward. The event was coordinated by theCenter for Nanotechnology in Drug Delivery, UNC’s Institute for Nanomedicine, and The Carolina Partnership, an $18 million fund created by the UNC Eshelman School of Pharmacy and the University Cancer Research Fund to support the School’s research centers. PHOTOS FROM THE CONFERENCE https://www.flickr.com//photos/uncpharmacy/sets/72157623277309237/show/
Speakers Set for Chapel Hill Drug Conference: Nanotech Is the Topic
April 14, 2009Application of nanotechnology to cancer, siRNA delivery, infectious diseases and vaccines, imaging and diagnostics, as well as nanomaterials engineering, nanotoxicology, and regulatory considerations in obtaining FDA-approved nano-based products will be the topics of this year’s Chapel Hill Drug Conference at the University of North Carolina at Chapel Hill. The conference, titled “The Use of Nanotechnology to Create Safe and Effective Therapeutic and Diagnostic Products,” will be hosted on campus by the UNC Eshelman School of Pharmacy and held in Kerr Hall on May 13 and 14. Nanotechnology is the control and manipulation of structures at the atomic and molecular level, … Read more
Undergraduate Student in Mumper’s Lab Selected for Workshop
April 1, 2009Eric Butter, a junior at the University of North Carolina at Chapel Hill, was selected by the National Institute of Allergy and Infectious Diseases to attend a workshop for academically talented, undergraduate and graduate students performing research in allergy, immunology, and infectious diseases. Only 23 students were selected out of 203 applicants for the Intramural NIAID Research Opportunities program. The four-day workshop, held Feb. 2-5, gave students the opportunity to learn about research and training opportunities in NIAID’s Division of Intramural Research, hear scientific lectures and participate in informal discussions with world-renowned researchers within the various NIAID laboratories, tour NIAID … Read more
UNC Announces Fourth Annual Chapel Hill Drug Conference
November 14, 2008Application of nanotechnology to cancer, siRNA delivery, infectious diseases and vaccines, imaging and diagnostics, as well as nanomaterials engineering and nanotoxicology will be the topics of this year’s Chapel Hill Drug Conference at the University of North Carolina at Chapel Hill. The conference, titled “The Use of Nanotechnology to Create Safe and Effective Therapeutic and Diagnostic Products,” will be hosted by the UNC Eshelman School of Pharmacy and held in Kerr Hall on May 13 and 14. Nanotechnology is the control and manipulation of structures at the atomic and molecular level, generally those smaller than 100 nanometers in size. A … Read more