Kenan Professor Kim L. R. Brouwer, PharmD, PhD, has been named associate dean of research and graduate education at the UNC Eshelman School of Pharmacy. Angela Kashuba, PharmD, the John A. and Deborah S. McNeill Jr. Distinguished Professor, will succeed Brouwer as chair of the Division of Pharmacotherapy and Experimental Therapeutics.
Brouwer is the William R. Kenan Jr. Distinguished Professor in DPET and a professor in the curriculum in toxicology in the School of Medicine. She served as the DPET chair from 2004 until her appointment as associate dean. She previously served as the School’s director of graduate studies from 1996 to 2004.
Brouwer directs an NIH-funded research program focused on hepatobiliary drug disposition and development and refinement of in vitro model systems to predict in vivo hepatobiliary disposition, drug interactions, and hepatotoxicity. She has mentored more than eighty-five undergraduate, graduate, and postdoctoral students and published more than 295 research papers, abstracts, and book chapters. She joined the School in 1986.
After receiving her BS in pharmacy from Oregon State University, Brouwer completed her PharmD at the University of Kentucky College of Pharmacy in conjunction with a pharmacy residency at the UK Medical Center. She went on to earn a PhD in pharmaceutical sciences/pharmacokinetics at UK and completed a postdoctoral fellowship in pharmacology and drug metabolism at the UK College of Medicine.
Brouwer is a co-inventor of B-CLEAR (U.S. Patent No. 6,780,580), an in vitro method to assess hepatic uptake, excretion, and biliary clearance that correlates with in vivo data. This technology has been exclusively licensed from the University of North Carolina at Chapel Hill to Qualyst, Inc., a UNC Eshelman School of Pharmacy biotechnology spin-off company. Brouwer is a cofounder of Qualyst.
From 1998 to 2002 Brouwer served as a member of the NIH Pharmacology Study Section and is a member of the editorial boards for Drug Metabolism and Disposition, Clinical Pharmacology and Therapeutics, CPT Pharmacometrics and Systems Pharmacology, and the AAPS PharmSci. She was elected an AAPS Fellow in 1998, was recipient of the PhRMA Foundation Award in Excellence in Pharmaceutics in 2001, and received the inaugural Pharmaceutical Sciences Outstanding Graduate Program Alumni Award and the Paul F. Parker Award from the University of Kentucky.