Recent Publications

1. Curran, D. P.; Zhang, Q.; Lu, H.; Gudipati, V. On the Proof and Disproof of Natural Product Stereostructures: Characterization and Analysis of a Twenty-Eight Member Stereoisomer Library of Murisolins and Their Mosher Ester Derivatives. J. Am. Chem. Soc. 2006, 128, 9943–9956.

2. Curran, D. P.; Zhang, Q.; Richard, C. R.; Lu, H.; Gudipati, V. Total Synthesis of a Twenty-eight Member Stereoisomer Library of Murisolins. J. Am. Chem. Soc. 2006, 128, 9561–9573.

3. Chen, S.; Do, J.; Zhang, Q.; Yao, S.; Yan, F.; Scholer, H. Schultz, P. G.; Ding, S. Maintenance of human and mouse embryonic stem cells self-renewal by a small molecule. Proc. Natl. Acad. Sci. U. S. A. 2006, 103, 17266–17271.

4. Zhang, Q.; Major, B.; Takanashi, S.; Camp, N. D.; Nishiya, N.; Peters, E. C.; Ginsberg, M.; Schultz, P. G.; Moon, R. T.; Ding, S. A Small Molecule Synergist of the Wnt/β-catenin Signaling Pathway. Proc. Natl. Acad. Sci. U. S. A. 2007, 104, 7444–7448.

5.  Chen, S.; Takanashi, S.; Zhang, Q.; Xiong, W.; Peters, E.C.; Ding, S.; Schultz, P.G. Reversine Induces Cellular Reprogramming of Lineage-Committed Mammalian Cells. Proc. Natl. Acad. Sci. U. S. A. 2007, 104, 10482-10487.

6. Song, Z. and Zhang, Q. Fluorous Aryl Diazirine Photoaffinity Labeling Reagents. Org. Lett. 2009, 11, 4883-4885.

7. Jones, C. A.; Nishiya, N.; London, N. R.; Zhu, W.; Sorensen, L. K.; Chan, A.; Lim, C. J.; Chen, H.; Zhang, Q.; Schultz, P. G.; Hayallah, A. M.; Thomas, K. R.; Famulok, M.; Zhang, K.; Ginsberg, M. H.; Li, D. Y. Slit2-Robo4 Signaling Promotes Vascular Stability by Blocking Arf6 Activity. Nature Cell Biol. 2009, 11, 1325-1331.

8. Liu, R.; Xu, R.; Chen, M.; Weiwer, M.; Zhou, X.; Bridges, A. S.; DeAngelis, P. L.; Zhang, Q.; Linhardt, R. J.; Liu, J. Chemoenzymatic Design of Heparan Sulfate Oligosaccharides. J. Biol. Chem. 2010, 285, 34240-34249.

9. Huang, W.; Hicks, S. N.; Sondek, J.; Zhang, Q. A Fluorogenic, Small Molecule Reporter for Mammalian Phospholipase C Isozymes. ACS Chem. Biol. 2011, 6, 223-228.

10. Sun, W.; Vanhooke, J.; Sondek, J.; Zhang, Q. High Throughput Fluorescence Polarization Assay for the Enzymatic Activity of GTPase-activating Protein of ADP-ribosylation Factor (ARFGAP). J. Biomol. Screen. 2011, 16, 717-723.

11. Huang, W.; Jiang, D.; Wang, X.; Sims, C. E.; Allbritton, N. L.; Zhang, Q. Kinetic Analysis of PI3K Reactions with Fluorescent PIP₂ Derivatives. Anal. Bioanal. Chem. 2011, 401, 1881-1888.

12. Song, Z.; Zhang, Q. Design, Synthesis, and Incorporation of Fluorous 5-Methylcytosines into Oligonucleotides. J. Org. Chem. 2011, 76, 10263-10268.

13. Song, Z.; Huang, W.; Zhang, Q. Isotope-coded, Fluorous Photoaffinity Labeling Reagents. Chem. Commun. 2012, 48, 3339-3341.