Brian Ferslew, Pharm.D.

E-mail: bferslew@unc.edu

Brian’s current research is focused on the exploration of the transport and metabolism processes involved in the disposition of drugs used in the treatment of hypertension and heart failure.  Brian will use mathematical pharmacokinetic and pharmacodynamic models to describe the disposition of these drugs, and thereby expects to allow the prediction of drug-drug interactions.

Latoya Griffin, B.S.

E-mail: poolelm@email.unc.edu

Latoya is investigating the mechanisms of hepatotoxicity associated with antiretroviral agents. Her research is focused specifically on the effect of lopinavir and ritonavir, alone and in combination, on bile acid transport and increased intracellular concentrations of protease inhibitors in vitro.

Nathan Pfeifer, Pharm.D.

E-mail: npfeifer@email.unc.edu

Nathan is researching clinically relevant hepatic transport drug-drug interactions.

Kevin Watt, M.D.

Email: wattk@email.unc.edu

Kevin's research interests include pharmacokinetics of drugs in critically ill children and dosing changes associated with extracorporeal life support. His current research is focused on antifungal prophylaxis in children supported with extracorporeal membrane oxygenation (ECMO).

Kyunghee Yang, M.S.

E-mail: kyang12@unc.edu

Kyunghee's research focuses on defining the mechanisms of drug-induced liver injury involving the interactions in efflux of bile acids and drugs. She is investigating troglitazone-mediated hepatotoxicity in transporter knockout sandwich-cultured rat hepatocytes.