Publications

Michel Weiwer, Trevor Sherwood, Dixy E. Green, Paul L. DeAngelis, Jian Liu, Robert J. Linhardt* (2008) Synthesis of uridine 5’-diphosphoiduronic acid (UDP-IdoA) as a potential unnatural substrate of glucuronosyltransferases for the chemoenzymatic synthesis of heparin. J. Org. Chem. (in press).
Zhenqing Zhang, Scott A. McCallum, Jin Xie, Lidia Nieto, Francisco Corzana, Jesús Jiménez-Barbero, Miao Chen, Jian Liu, Robert J. Linhardt* (2008) Solution structures of chemoenzymatically synthesized heparin and its precursors. J. Am. Chem. Soc. (in press).
Ronald Copeland, Arun Balasubramaniam, Vaibhav Tiwari, Arleen Bridges, Robert J Linhardt, Deepak Shukla, and Jian Liu* (2008) Using a 3-O-sulfated heparin octasaccharide to inhibit the entry of herpes simplex virus 1 Biochemistry 47: 5774-5783.
Xu, D., Moon, A.F., Song, D., Pedersen, L.C. and Liu*, J. (2008) Engineering the sulfotransferases to modify heparan sulfate Nat. Chem. Biol. 4: 200-202.

→ more

Chen, J., Jones, C.L., and Liu*, J. (2007) Using an enzymatic combinatorial approach to identify novel anticoagulant heparan sulfate structures Chemistry & Biology 14: 986-993 (Commentary by Linhardt, R.J. and Kim, J.-H. (2007) Chemistry & Biology 14: 972-973)
Xu, D., Song, D., Pedersen, L. and Liu*, J. (2007) Mutational study of heparan sulfate 2-O-sulfotransferase and chondroitin sulfate 2-O-sulfotransferase J. Biol. Chem. 282: 8356-8367.

→ more

→ more papers

Robert J Linhardt*, Jonathan S. Dordick, Paul DeAngelis, Jian Liu (2007) Enzymatic synthesis of glycosaminoglycan heparin Semin. Thromb. Hemost. 33: 453-465.
Jian Liu* and Lars C. Pedersen (2007) Anticoagulant heparan sulfate: Structural specificity and biosynthesis. Appl. Microbiol. Biotechnol. 74:263-272.
Jian Liu* and Suzanne C. Thorp (2001) Cell surface heparan sulfate and the roles in assisting viral infections. Med. Res. Rev. 22:1-25.
Robert D. Rosenberg*, Nicholas W. Shworak, Jian Liu, John J. Schwartz, and Lijuan Zhang (1997) Heparan sulfate proteoglycans of the cardiovascular system: specific structures emerge but how is synthesis regulated J. Clin. Invest. 99: 2062-2070.
Robert J. Linhardt*, Jian Liu and Xue-jun Han (1993) Mapping and sequencing of oligosaccharides by electrophoresis. Trends Glycosci. Glycotechnol. 5: 181-192.

Fikri Y. Avci, Paul L. DeAngelis, Jian Liu, and Robert J. Linhardt* (2007) Enzymatic synthesis of glycosaminoglycans: improving on nature, in Frontiers in Carbohydrate Chemistry, pp 253-284.
Jian Liu* and Robert D. Rosenberg (2001) Heparan sulfate D-glucosaminyl 3-O-sulfotransferase, in Handbook of Glycosyltransferases and Their Related Genes (N. Taniguchi and M. Fukuda Eds.) Springer-Verlag, Tokyo pp 475-483. (Book Chapter)
Robert J. Linhardt*, Ali Al-Hakim and Jian Liu (1991) Acidic polysaccharides: Their modification and potential uses, in Biotechnology and Polymers (C. G. Gebelein Ed.) Plenum Press, new York, 155-165. (Book Chapter)