Current Research Projects
Current Research Projects
The Kashuba Lab is engaged in a number of research projects. Current studies include the following sponsored research:
- Kashuba ADM, Principal Investigator. The Effect of Silymarin on Fibrosis in Patients with Hepatic Disease, sponsored by the NIH/CAM.
- Kashuba ADM, Principal Investigator. First-Dose and Steady-State Pharmacokinetics of Raltegravir in the Genital Tract of HIV-Infected and HIV Uninfected Women, funded by Merck.
- Kashuba ADM, Principal Investigator. A phase IV open-label study to characterize extracellular and intracellular tenofovir/emtricitabine residues in multiple biological matrices after a single dose: implications for pre-exposure HIV prophylaxis dosing of Truvada®, supported by Gilead.
- Kashuba ADM, Principal Investigator. A phase IV, open label study in healthy male subjects to investigate the extent of maraviroc exposure in blood, saliva, seminal fluid, and rectal mucosal tissue following single and multiple dosing, funded by Pfizer, Inc.
- Kashuba ADM, Principal Investigator. Fesibility of CCR5 Inhibitors in Preventing Maternal to Infant SIV Transmission, funded by the NIAID.
- Kashuba ADM, Patterson KB, Co-Principal Investigators. The Effect of Pregnancy on the Pharmacokinetics of the Kaletra Tablet: A Longitudinal Investigation in the Second and Third Trimesters Including Empiric Dosage Adjustment. Abbott, Inc. (Investigator-Initiated Research).
- Corbett, A, Co-Investigator. Impact of malnutrition on TB IRIS and pharmacokinetics of TB and HIV co-treatment. NIH/NICHD.
- Corbett, A, Co-Investigator. HIV Infection and Breastfeeding: Interventions for Maternal and Infant Health. Centers for Disease Control, Special Interest Project 13-01.
- Corbett, A, Co-Investigator. Ryan White Comprehensive AIDS Resources Emergency Act Title III Grant. US DHHS/Health Resources and Services Administration/HIV/AIDS Bureau.
- Dumond J, Principal Investigator; Corbett A, Kashuba ADM, Patterson KB Co-Investigators. Atripla pharmacokinetics in the aging HIV-infected population. Society of Infectious Diseases Pharmacists.
