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Administrative Contact:
Barbara Dearry
919-843-0766
dearry@email.unc.edu

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Resources and Portfolio

Resources & Portfolio

The Center was initiated with funding from across the University and a significant contribution from the Cancer Research Fund (recently created by the State legislature). This initial funding and the facilities devoted to the Center, combined with NIH grant and contract awards, have enabled

Recruitment of:

  • 11 medicinal/synthetic chemists – including two research Professors
  • 8 assay development & compound profiling scientists – including one research Professor
  • 2 computational/informatics scientists - including one research Professor

The Center has acquired:

  • Compound collection of approx. 106,280 maximally diverse small molecules available for screening including

►100K diversity screening compounds

►Kinase targeted set of 15K compounds

►LOPAC set of 1.2K compounds

  • Capability to outsource synthetic chemistry to enhance productivity
  • Capability to develop cellular and biochemical based screens utilizing multiple technologies including

►fluorescence (FLINT, FP, FRET, HTRF)

►luminescence (reporter, BRET)

►radioactive binding

►AlphaScreen

►FLIPR

►microfluidity mobility shift

Portfolio Model

 2011 Portfolio Goals

 For a list of portfolio projects click here

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