November 7, 2007
Students from the UNC School of Pharmacy will present posters at the American Association of Pharmaceutical Scientists Annual Meetings and Expositions at the San Diego Convention Center on November 13-14.
The students are:
Koji Abe, PhD — Visiting Scholar
Faculty adviser: Kim Brouwer, PhD
Division: Pharmacotherapy and Experimental Therapeutics
Title of Abstract: “In Vitro Biliary Clearance of Angiotensin II Receptor Blockers and HMG-CoA Reductase Inhibitors in Sandwich-Cultured Rat Hepatocytes — Comparison to In Vivo Biliary Clearance”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Dan Bow, PhD
Faculty adviser: Kim Brouwer, PhD
Division: Pharmacotherapy and Experimental Therapeutics
Title of Abstract: “P-gp (Abcb1) and Mrp2 (Abcc2) localization in freshly-isolated rat hepatocytes”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Lucila Garcia-Contreras
Faculty adviser: Athony Hickey, PhD
Title of Abstract: 1) “Pharmacokinetics of Inhaled capreomycin particles in the guinea pig”
2) “Efficacy of inhaled capreomycin particles for the treatment of tuberculosis in the guinea pig”
Session Date: Monday, November 12
Session Time: 1:00-5:00 p.m.
Location: Exhibition Hall
Wujian Ju
Faculty adviser: J Ed Hall, PhD
Division: Molecular Pharmaceutics
Title of Abstract: “Anti-trypanosomal Drug Metabolite DB775 Induces Apoptosis in MCF-7 Cells”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Beverly Knight
Faculty adviser: Dhiren Thakker, PhD
Division: Molecular Pharmaceutics
Title of Abstract: “Why is Metabolism Higher during Absorptive vs. Secretory Transport across Intestinal Epithelium?”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Jin K Lee
Faculty adviser: Kim Brouwer, PhD
Division: Pharmacotherapy and Experimental Therapeutics
Title of Abstract: “Modulation of ET-743 Hepatobiliary Disposition by Multidrug Resistance-Associated Proteins (Mrps) May Protect the Liver from Hepatotoxicity”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Shyh-Dar Li/Sumio Chono/Leaf Huang, PhD
Faculty adviser: Leaf Huang, PhD
Division: Molecular Pharmaceutics
Title of Abstract: “Efficient Gene Silencing in Lung Metastasisby Systemically Delivered siRNA”
Session Date: Tuesday, November 13
Session Time: 9:35 p.m.
Dongmei Lu
Faculty adviser: Athony Hickey, PhD
Title of Abstract: “Pulmonary delivery of recombinant antigen 85B in microparticulate vaccine systems for protection against Tuberculosis”
Session Date: Monday, November 12
Session Time: 8:00 a.m.
Location: Exhibition Hall
Heidi Mansour, PhD/Zhen Xu
Faculty adviser: Athony Hickey, PhD
Title of Abstract: “Characterization of Dry Powder Aerosols of Albuterol Sulfate and Cromolyn Sodium with Various Sugar Carriers Delivered by Standardized Entrainment Tubes.”
Session Date: Wednesday, November 14
Session Time: 1:00-5:00 p.m.
Location: Exhibition Hall
Xin Ming
Faculty adviser: Dhiren Thakker, PhD
Division: Molecular Pharmaceutics
Title of Abstract: “Role of Human Organic Cation/Carnitine Transporter OCTN2 (SLC22A5) in Intestinal Absorption of Zwitterionic Drugs”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Xin Ming (in collaboration with the Hall Lab)
Faculty adviser: Dhiren Thakker, PhD
Division: Molecular Pharmaceutics
Title of Abstract: “Differential Oral Absorption of the Antitrypanosomal Diamidine Compounds DB829, DB75, and DB820 in Mice”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Pavan Muttil
Faculty adviser: Athony Hickey, PhD
Title of Abstract: 1) “Spray drying of GFP tagged Pseudomonas aeruginosa in Alginate Microparticles”
2) “Spray drying of GFP tagged Pseudomonas aeruginosa in Alginate Microparticles”
Session Date: November, 12
Session Time: 1:00-5:00 p.m.
Location: Exhibition Hall
Session Date: 11/12/2007 1:00 PM 5:00 PM
Exhibition Hall
Will Proctor/Yan Gao, PhD
Faculty adviser: Dhiren Thakker, PhD
Division: Molecular Pharmaceutics
Title of Abstract: “Development of a High Throughput 96-well Transwell MDCK II Cell-based Screen to Identify Intestinal Tight Junction Permeability Enhancers”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Brandon Swift
Faculty adviser: Kim Brouwer, PhD
Division: Pharmacotherapy and Experimental Therapeutics
Title of Abstract: “Impact of Basolateral Multidrug Resistance-Associated Proteins (Mrp) 3 (Abcc3-/-) and Mrp4 (Abcc4-/-) on the Hepatic Disposition of Fexofenadine (FEX) in Mice”
Session Date: Tuesday, November 13
Session Time: 1:00-5:00 p.m.
Location: Exhibit Hall
Chenchen Wang
Faculty adviser: Athony Hickey, PhD
Title of Abstract: “Preparation, Characterization, and Cellular Response to Microparticles Containing Muramyl Dipeptide and Trehalose Dibehenate.”
Session Date: Monday, November 12
Location: Exhibition Hall
Kristina Wolf, PhD
Faculty adviser: Kim Brouwer, PhD
Division: Pharmacotherapy and Experimental Therapeutics
Title of Abstract: “Effect of Albumin and Free Fatty Acids on the Hepatobiliary Disposition of Digoxin in Sandwich-Cultured Rat Hepatocytes”
Session Date: Wednesday, November 14
Session Time: 8:00 am-12:00 pm
Location: Exhibit Hall
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