Singleton Research Group

Scott F Singleton Ph.D.

Associate Professor
Medicinal Chemistry and Natural Products

Office
UNC School of Pharmacy
CB # 7360
Beard Hall, Room # 323
Chapel Hill, NC 27599-7360

Phone
919-966-7954

Fax
919-966-0204

Email
sfs@email.unc.edu

 

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Research Philosophy

Our laboratory is interested in the discovery and exploitation of new strategies for controlling drug-resistant microorganisms.  In one project area, we are investigating the initiation of DNA repair in bacteria as a functional target for controlling bacterial survival in the absence of traditional antibiotics.  In a second project area, we are developing methods to perform high-throughput screening of billions of protein variants in order to investigate the inhibition of proteases found in microbial human pathogens such as HIV, hepatitis C virus, and a range of bacteria.