| The Functional Proteomics Laboratory at School of Pharmacy and Carolina Center for Genome Sciences |
Rihe
Liu
Ph.D.
Associate Professor |
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Natural Caspase Substrate Repertoire in Human
This project aims at identifying from the human proteome the family member-specific natural substrate repertoire of each caspase in the mammalian caspase family. The project is funded by the National Institute of Neurological Disorders and Stroke. We have finished the proteome-wide selections of the downstream substrates of the following caspase members:
1. Caspase-2
2. Caspase-3
3. Caspase-6
4. Caspase-8
5. Caspase-9
6. Caspase-10