Natural Products Research Laboratories
Document Actions
The Natural Products Research Laboratories (NPRL) has established an exceptional research program in rational drug discovery. Current research programs in the NPRL include the following:
- Medicinal Chemistry
- Bioactive Natural Products
- New Anticancer and Anti-AIDS Drug Discovery and Development
- Chinese Medicine
Dr. Lee combines the fields of natural products and synthetic medicinal chemistry research to discover and develop bioactive natural products and their analogs as clinical trials drug candidates. Since 1971, the NPRL has discovered more than 3,000 novel bioactive natural products and synthetic analogs. These discoveries are used as new leads to develop future pharmaceuticals agents in the same manner that numerous previously discovered bioactive natural products (including ephredrine, taxol, and artemisinin) were developed as current pharmaceutical agents to treat cancers and other diseases. Using basic natural products and medicinal chemistry principles coupled with modern technologies, including new computational techniques and new target-based and genomic evaluation methods, our newly discovered lead compounds will provide a solid foundation of potential chemotherapeutic drug candidates in the 21st century.