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“In both [natural and social sciences], there is no ‘certain’ substantive knowledge; only tentative hypotheses that can never be "proved" but can only fail to be rejected, hypotheses in which we may have more or less confidence, depending on such features as the breadth of experience they encompass relative to their own complexity and relative to alternative hypotheses, and the number of occasions on which they have escaped possible rejection.”
- Milton Friedman
Lecture upon receipt of1976 Nobel Prize for Economics