Latest Publications

This list contains articles published since 2004

264.     Tyagi, P., Chancellor, M., Li, Z., de Groat, Wm., Yoshimura, N., Fraser, M., and Huang, L.  Urodynamic and immunohistochemical evaluation of intravesical capsaicin delivery using thermosensitive hydrogel  & liposomes. J. of Urology, 171: 483-489, 2004.

265.     Liu, F., Lei, J., Vollmer, R., and Huang, L.  Mechanism of liver gene trasfer by mechanical massage.  Molecular Therapy, 9: 452-457, 2004.

266.     Tyagi, P., Li, Z., Chancellor, M., De Groat, W., Yoshimura, N., and Huang, L.  Sustained intravesical drug delivery using thermosensitive hydrogel.  Pharmaceutical Research, 21: 832-837, 2004.

267.     Stabile, L.P., Lyker, J.S., Huang, L. and Siegfried, J.M.  Inhibition of human non-small cell lung tumors by a c-Met antisense/U6 expression plasmid strategy.  Gene Therapy.  11: 325-335, 2004.

268.     Cui, Z., Han, S-J, Huang, L.  Coating of mannan on LPD nanoparticles containing HPV E7 peptide significantly enhanced immunity against HPV-positive tumor. Pharmaceutical Research, 21:1018-1025, 2004.

269.     Liang, K., Nishikawa, M., Liu, F., Sun, B., Ye, Q. and Huang, L.  Restoration of dystrophin expression in mdx mice by intravascular injection of naked DNA containing full-length dystrophin cDNA.  Gene Therapy, 11: 901-908, 2004..

270.     Lee, P-Y; Chesnoy, S.; and Huang, L.  Electroporatic delivery of TFG-B1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice.  J. of Investigative Dermatology.  123:  791-798. 2004.

271.     Li, Z. and Huang, L.  Sustained delivery and expression of plasmid DNA based on biodegradable polyester, poly (D, L-lactide-co-4-hydroxy-L-proline).  J. of Controlled Release, 98: 437-446, 2004.

272.     Banerjee, R., Tyagi, P., Li, S., and Huang, L. Anisamide-targeted stealth liposomes:  a potent carrier for targeting doxorubicin to human prostate cancer cells.  International J. of Cancer. 112: 693-700, 2004.

273.     Liu, F., Shollenberger, L., and Huang, L.  Non-immunostimulatory nonviral vectors. FASEB J. 18: 1779-81, 2004.

274.     Hyndman, L., Lemoine, J.L., Huang, L., Porteous, D.J., Boyd, A.C., and Nan, X.  HIV-1 Tat protein transduction domain peptide facilitates gene transfer in combination with cationic liposomes.  J. of Controlled Release.  99: 435-444, 2004.

275.     Cui, Z., Han, S-J, Vangasseri, D-P, and Huang, L. The immunostimulation mechanism of LPD nanoparticles.  Molecular Pharmaceutics.  2: 22-28, 2005.

276.     Cui, ZR. and Huang, L.  Liposome-polycation-DNA (LPD) particle as a carrier and adjuvant for protein-based vaccines:  Therapeutic effect against cervical cancer.  Cancer Immunol. Immunother. 54: 1180-1190, 2005.

277.     Lemoine, J. and Huang, L. Mechanism of efficient transfection of the nasal airway epithelium by hypotonic shock. Gene Therapy. 12: 1275-1282, 2005.

278.     Wilson, A., Zhou, W., Champion, H., Alber, S., Tang, Z-L, Kennel, S., Watkins, S., Huang, L., Pitt, B., and Li, S. Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo.  Molecular Therapy. 12: 510-518, 2005.

279.     Zhang, J., Liu, F., Conwell, C., Tan, Y. and Huang, L. Mechanistic studies of sequential injection of cationic liposome and plasmid DNA. Molecular Therapy. 13:429-437, 2006.

280.     Liu, F., Heston, S., Shollenberger, L.M., Sun, B., Mickle, M., Lovell, M. and Huang, L.  Mechanism of in vivo DNA transport into cells by electroporation: electrophoresis across the plasma membrane may not be involved. J. Gene Med. 8:353-361. 2006.

281.     Mu, Y., Zhang, J., Zhang, S., Toma, D., Ren, S., Huang, L. Yaramus, M.,, Baum, A., Venkataramanan, R., and Xie, W. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate PXR and increase Warfarin clearance in rats. J. Pharmacol. Expt. Therap. In press.

282.     Tyagi, P., Banerjee, R., Basu, S., Yoshimura, N., Chancellor, M., Huang, L. Intravesical Antisense Therapy For Cystitis Using TAT-Peptide Nucleic Acid Conjugates.  Molecular Pharmaceutics. In Press.

283.     Vangasseri, D. and Huang, L. Immunostimulation of dendritic cells by cationic lipids. Molecular Membrane Biology. In Press

284.    Tyagi, P., Banerjee, R., Basu, S., Yoshimura, N., Chancellor, M., and Huang, L. Intravesical Antisense Therapy for Cystisis Using TAT-Peptide Nucleic Acid Conjugates.  Molecular Pharmaceutics, 3: 398-406, 2006.

285.    Li, S., Huang, L. Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells. Molecular Pharmaceutics. 3(5): 579-588, 2006.

286.    Olton, D., Li, J., Wilson, M.E., Rogers, T., Close, J., Huang, L., Kumta, P.N., and Sfeir, C.  Nanostructured Calcium Phosphates (NanoCaPs) for Non-Viral Gene Delivery: Influence of the Synthesis Parameters on Transfection Efficiency.  Biomaterials. 28: 1267 - 1279, 2007.

287.    Lee, P.Y., Cobain, E., Huard, J., and Huang, L.  Thermosensitive Hydrogel PEG-PLGA-PEG Enhances the Engraftment of Muscle-Derived Stem Cells and Promotes Healing in Diabetic Wound. Molecular Therapy. 15(6): 1189 – 1194, 2007.

288.    Liu, F., Conwell, C.C., Yuan, X., Shollenberger, L.M., and Huang, L. Novel Non-viral Vectors Target Cellular Signaling Pathways: Regulated Gene Expression and Reduced Toxicity.  J. Pharmacol. Expt. Therap. 321:777-783, 2007.

289.    Liu, F., Shollenberger, L.M., Conwell, C.C., Yuan, X., and Huang, L. Mechanism of Naked DNA Clearance After Intravenous Injection.  J. Gene Med. 9:613-619, 2007.

290.    Yan, W., Chen, W.C. and Huang, L. Mechanism of Adjuvant Activity of Cationic Lipsome: Phosphorylation of a Map Kinase, ERK and Induction of Chemokines. Molecular Immunology. 44: 3672 -3681, 2007.

291.    Chen, W., Yan, W., and Huang, L. A Simple but Effective Cancer Vaccine Consisting of an Antigen and a Cationic Lipid.  Cancer Immunology Immunotherapy.  57:517-530, 2008.

292.   Li, S-D., Chen, Y-C., Hackett, M.J. and Huang, L. Tumor Targeted Delivery of siRNA by Self-assembled Nanoparticles. Molecular Therapy. 16(1):163 -169, 2008

293.   Conwell, C.C., Liu, F., and Huang, L. Several Serum Proteins Significantly Decrease Inflammatory Response to Lipid Based Nonviral Vectors. Molecular Therapy.  16:370 - 377, 2008.

294.  Li, S-D., and Huang, L.  Efficient Gene Silencing in Metastatic Tumor by siRNA Formulated in Surface-modified Nanoparticles. Journal of Controlled Release. 126:77 - 84, 2008.

295. Li, S-D.,  Chono, S., and Huang, L. Efficient Oncogene Silencing in Matastasis Inhibition via Systemic Delivery of siRNA. Molecular Therapy 16(5):942 - 946, 2008.

296. Tyagi, P., Chancellor, M., Yashimura, N., and Huang, L. Activity of Different Phospholipids in Attenuating Hyperactivity in Bladder Irritation.  BJU International. 101:627 - 632, 2007.

297. Chen, W., and Huang, L. Induction of cytotoxic T-lymphocytes and anti-tumor activity by a liposomal lipopetide vaccine.  Molecular Pharmaceutics. 5(3): 464 - 471, 2008.

298. Yan, W., Chen, W., and Huang L. Reactive Species Play a Central Role in the Activity of Cationic Liposome Based Cancer Vaccine.  Journal of Controlled Release.  In press.

299.  Chono, S., Li, S-D., Conwell, C.C., and Huang, L. An Efficient and Low Immunostimulatory Nanoparticle Formulation for Systemic siRNA Delivery to the Tumor. Journal of Controlled Released.  311: 64 - 69, 2008.

300. Yan, W. and Huang, L. The Effects of Salt on the Physiochemical Properties and Immunogenicity of Protein Based Vaccine Formulated in Cationic Liposome.  International Journal of Pharmaceutics.  In press.

301. Chen Y, and Huang, L. Tumor Targeted Delivery of siRNA by Non-Viral Vector: Safe and Effective Cancer Therapy.  Expert Opin. Drug Deliv. 5(12): 1301 - 1311, 2008.

302. Gao, K and Huang, L. Non-viral Methods for siRNA Delivery. Molecular Pharmaceutics. In press.