Before 2000

This list contains articles published between 1997 and 1999

183.    Chang, J.Y., Xia, W., Shano, R., Sorgi, F., Huang, L. and Hung, M.-C. The tumor suppressing activity of E1A in HER-2/neu-overexpressing versus low expressing breast cancer. Oncogene. 14:561-568, 1997.

184.    MacVinish, L.J., Gill, D.R., Hyde, S.C., Mofford, K.A., Evans, M.J., Higgins, C.F., Colledge, W.H., Huang, L., Sorgi, F., Ratcliff, R. and Cuthbert, A.W. Chloride secretion in trachea of null cystic fibrosis mice: the effects of transfection with pTtrial10-CFTR1. J. of Physiology, 499.3:677-687, 1997.

185.    Shurin, G., Shanks, N., Nelson, L., Hoffman, G., Huang, L. and Kusnecov, A.W. Hypothalamic-pituitary-adrenal activation by the bacterial superantigen staphylococcal enterotoxin B: role of macrophages and T cells. Neuroendocrinology, 65:18-28, 1997.

186.    Xing, X., Liu, V., Xia, W., Stephens, L.C., Huang, L., Lopez-Berestein, G., Hung, M-C. Safety studies of the intraperitoneal injection of E1A-liposome complex in mice. Gene Therapy, 4:238-243, 1997.

187.    Gill, D.R., Southern, K.W., Mofford, K.A., Seddon, T., Huang, L., Sorgi, F., Thomson, A., McVinish, L.J., Ratcliff, R., Bilton, D., Lane, D.J., Littlewood, J.M., Webb, A.K., Middleton, P.G., Colledge, W.H., Cuthbert, A.W., Evans, M.J., Higgings, C.F., and Hyde, S.C. A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Therapy, 4:199-209, 1997.

188.    Li, S., Brisson, M., He, Y., and Huang, L. Delivery of PCR amplified DNA fragment into cells: a model for using synthetic genes for gene therapy. Gene Therapy, 4:449-454, 1997.

189.    Liu, F., Qi, H., Huang, L., and Liu, D. Factors controlling efficiency of cationic lipid-mediated transfection in vivo via intravenous administration. Gene Therapy, 4:517-523, 1997.

190.    Ferro, W.G., Li, S., Rosenblatt, J.D., Sirianni, N., Morgan, J.E., Partridge, T.A., Huang, L. and Hoffman, E.P. Selection and use of ligands for receptor-mediated gene delivery to myogenic cells. Gene Therapy, 4:664-674, 1997.

191.    Davies, J.C., Stern, M., Dewar, A., Caplen, N.J., Munkonge, F.M., Pitt, T., Sorgi, F., Huang, L., Bush, A., Gedes, D.M., and Alton, E.W.F.W. CFTR gene transfer reduces the binding of pseudomonas aeruginosa to cystic fibrosis respiratory epithelium. Am. J. Resp. Cel. Mol. Biol., 16:657-663, 1997.

192.    Yang, K., Mu, X-S, Hayes, R.L., Qiu, Y.H., Sorgi, F.L., Huang, L., and Clifton, G.L. DC-chol liposome-mediated gene transfer in rat spinal cord. Neuro Report, 8:2355-2358, 1997.

193.    Hui, K.M., Ang, P.T., Huang, L. and Tay, S.K. Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes. Gene Therapy, 4:783-790, 1997.

194.    Yang, J.P. and Huang, L. Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA. Gene Therapy, 4:950-960, 1997.

195.    Sorgi, F.L. Bhattacharya, S., and Huang, L. Protamine sulfate enhances lipid mediated gene transfer. Gene Therapy, 4:961-968, 1997.

196.    Li, S. and Huang, L. In vivo gene transfer via intravenous administration of cationic lipid/protamine/DNA (LPD) complexes. Gene Therapy, 4:891-900, 1997.

197.    He, Y. and Huang, L. Growth inhibition of HPV16 DNA positive mouse tumor by antisense RNA transcribed from U6 promoter. Cancer Res., 57:3993-3999, 1997.

198.    Hara, T., Tan, Y., and Huang, L. In vivo gene delivery to the liver using reconstituted chylomicron remnants as a novel non-viral vector. Proc. Natl Acad. Sci. USA 94:14547-14552, 1997. PMCID: PMC25050

199.    Yang, J.P. and Huang, L. Time-dependent maturation of cationic liposome-DNA complex for serum resistance. Gene Therapy.5:380-387, 1998.

200.    Goddard, C.A., Ratcliff, R., Anderson, J.R., Glenn, E., Brown, S., Gill, D.R., Hyde, MacVinish, L. J., Huang, L., Higgins, C.F., Cuthbert, A.W., Evans, M.J., and Colledge, W.H. A second dose of a CFTR cDNA-liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea. Gene Therapy. 4:1231-1236, 1997.

201.    Stern, M., Caplen, N.J., Browning, J.E., Griesenbach, U., Sorgi, F., Huang, L., Gruenert, D.C., Marriot, C., Crystal, R.G., Geddes, D.M., and Alton, E.W.F.W. The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro. Gene Therapy. 5: 91-98, 1998.

202.    Stern, M., Sorgi, F., Hughes, C., Caplen, N.J., Browning, J.E., Middleton, P.G., Gruenert, D.C., Farr, S.J., Huang, L., Geddes, and Alton, E.W.F.W. The effect of jet nebulisation on liposome mediated gene transfer across in vitro. Gene Therapy. 5:583-593, 1998.

203.    Li, S., Rizzo, M.A., Bhattacharya, S., and Huang, L. Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery. Gene Therapy. 5: 930-937, 1998.

204.    Li, S. and Huang, L. Targeted delivery of antisense oligodeoxynucleotides formulated in a novel lipidic vector. J. Liposome Res. 8: 239-250, 1998.

205.    Qiu, Y.H., Zhao, X., Hayes, R.L., Perez-Polo, J.R., Pike, B.R., Huang, L., Clifton, Gg.L., and Yang, K. Activation of phosphatidylinositol 3-Kinase by brain-derived neurotrophic factor gene transfection in septo-hippocampal cultures. J. Nuerosci. Res. 52: 192-200, 1998.

206.    Li, S., Deshmukh, H.M., and Huang, L. Folate-mediated targeting of antisense oligodeoxynucleotides to ovarian cancer cells. Pharma Res. 10: 1540-1545, 1998.

207.    He, Y., Lui, V., Barr, J., Wang, L., Shurin, M., Almonte, C., Watkins, S., and Huang, L. Potentiation of E7 antisense RNA induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor. Gene Therapy. 5: 1462-1471, 1998.

208.    Xing, X., Zhang, S., Chang, J.Y., Tucker, S.D., Chen, H., Huang, L., and Hung, M.-C. Safety study and characterization of E1A-liposome complex gene-delivery protocol in an ovarian cancer model. Gene Therapy. 5: 1538-1544, 1998.

209.    He, Y., Zeng, Q., Drenning, S., Melhem, M., Tweardy, D., Huang, L., and Grandis, J.R..  Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter.  J. Nat. Cancer Inst.  14: 1080-1087, 1998.

210.    Brisson, M., He, Y., Li, S., Yang, J-P, and Huang, L. A novel T7 RNA polymerase expression vector for efficient cytoplasmic expression of target genes. Gene Therapy. 6:263-270, 1999.

211.    Li, S., Tseng, W.C., Stolz, D.B., Wu, S.P., Watkins, S.C., and Huang, L. Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Therapy. 6: 858-594, 1999.

212.    Li, S., Wu, S.P., Whitmore, M. Loeffert, E.J., Wang, L., Watkins, S.C., Pitt, B.R.and Huang, L. Effect of immune response on gene transfer to the lung via systematic administration of cationic lipidic vectors. Am. J. Physiol. 276: L796-L804, 1999

213.    Nikitin, A.Y., Juarez, M.I., Li, S., Huang, L. and Lee, W.H. RB-mediated suppression of spontaneous multiple endocrine neoplasia and lung metastases in Rb+/- mice. Proc. Natl. Acad. Sci USA. 96: 3916-3921, 1999. PMCID: PMC22395

214.    Zou, L.L., Huang, L., Hayes, R.L., Black, C., Qiu, Y.H., Perez-Polo, J.R., Le, W., Clifton, G.L., and Yang, K. Liposome-mediated NGF gene transfection following neuronal injury: potential therapeutic applications. Gene Therapy. 6: 994-1005,1999

215.    Ueno, N.T., Xia, W., Tucker, S.D., Zhang, S., Lopez-Berenstein, G., Huang, L., and Hung, M.C. Issues in the development of gene therapy: Preclinical Experiments in E1A Gene Delivery. Oncology Reports 6:257-262, 1999.

216.    Kitson, C., Angel, B., Judd, D., Rothery, S., Severs, N.J., Dewar, A., Huang, L., Wadsworth, S.C., Cheng, S.H., Geddes, D.M., and Alton, EWFW. The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium. Gene Therapy. 6: 534-546, 1999.

217.    Savva, M., Duda, E., Huang, L., A genetically modified recombinant tumor necrosis factor-alpha conjugated to the distal terminals of liposomal surface grafted polyethyleneglycol chains. Intl. J.Pharmaceutics 184: 45-51, 1999.

218.    Tan., Y., Li, S., Pitt, B., and Huang, L. The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Human Gene Therapy. 10: 2153-2161, 1999.

219.    Savva, M. Torchilin, P. and Huang, L. Effect of Grafted Amphiphilic PVP-palmityl Polymers on the Thermotropic Phase Behavior of 1,2-dipalmitoyl-sn-glycero-3-phosphochline Bilayer. J. Colloid Interface Sci. 217: 166-171, 1999.

220.    Savva, M., Torchilin, P., Huang, L. Effect of Poly(vinylpyrrolidone) on the Thermal Phase Transition of 1,2 Dipalmitoyl1-sn-glycero-3-phosphocholine Bilayer. J. Colloid Interface Sci. 217: 160-165, 1999.

221.    Whitmore, M., Li, S., Huang, L. LPD lipopolyplex initiates a potent cytokine response and inhibits pulmonary tumor growth. Gene Therapy. 6:1867-1875, 1999

222.    Savva, M. and Huang, L. Effect of PEG homopolymer and grafted amphipilic PEG-palmityl on the thermotropic phase behavior of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine bilayer. J.Liposome Res. 9: 357-365, 1999.

223.    Brisson, M., Tseng, WC., Almonte, C., Watkins, S. and Huang, L. Subcelluar trafficking of the cytoplasmic expression system. Human Gene Therapy. 10:2601-2613, 1999.

224.    Chesnoy, S. and Huang, L. DNA condensed by polycations and lipids for gene transfer. S.T.P. Pharma Sci. 9:5-12, 1999.