Before 1991

This list contains articles published before January 1991

Dissertation:

1.    Structure and function of Acholeplasma membranes - effects of lipid chain length and carotenoid pigments. Ph.D. dissertation, Michigan State University, 1974.

Peer Reviewed Articles:

1.    Huang, L., Jaquet, D.D.and Haug, A. The effect of fatty acyl chain length on some structural and functional parameters of Acholeplasma membranes. Canad. J. Biochem. 52:483-490, 1974.

2.    Huang, L. and Haug, A. Regulation of membrane lipid fluidity in Acholeplasma laidlawii: effect of carotenoid pigment content. Biochim. Biophys. Acta 352:361- 370, 1974.

3.    Huang, L., Lorch, S.K., Smith, G. and Haug, A. Regulation of membrane fluidity in Acholeplasma laidlawii. FEBS Letters 43:1- 5, 1974.

4.    Hsung, J.C., Huang, L., Hoy, D. and Haug, A. Lipid and temperature dependence of membrane bound ATPase activity of Acholeplasma laidlawii. Canad. J. Biochem. 52:974- 980, 1974.

5.    Pagano, R.E., Huang, L. and Wey, C. Interaction of phospholipid vesicles with cultured mammalian cells. Nature 252:166, 1974.

6.    Huang, L. and Pagano, R.E. Interactions of phospholipid vesicles with cultured mammalian cells. I. characteristics of uptake. J. Cell Biol. 67:38- 48, 1974.

7.    Pagano, R.E. and Huang, L. Interaction of phospholipid vesicles with cultured mammalian cells. II. studies of mechanism. J. Cell Biol. 67:49- 60, 1975.

8.    Ozato, K., Huang, L. and Ebert, J.D. Accelerated calcium ion uptake in murine thymocytes induced by concanavalin A. J. Cell. Physiol. 93:153- 160, 1977.

9.    Huang, L., Ozato, K. and Pagano, R.E. Interactions of phospholipid vesicles with murine lymphocytes. I. vesicle- cell adsorption and fusion as alternate pathways of uptake. Memb. Biochem. 1:1- 25, 1978.

10.    Ozato, K., Huang, L. and Pagano, R.E. Interactions of phospholipid vesicles with murine lymphocytes. II. correlation between altered surface properties and enhanced proliferative response. Memb. Biochem. 1:27- 42, 1978.

11.    Wilkins, J.A., Greenawalt, J.W. and Huang, L. Transport of 5- hydroxytryptamine by dense granules from porcine platelets. J. Biol. Chem. 253:6260- 6265, 1978.

12.    Huang, L. Transmembrane nature of acetylcholine receptor as evidenced by protease sensitivity. FEBS Letters 102:9- 12, 1979.

13.    Huang, L. and Kennel, S.J. Binding of immunoglobulin G to phospholipid vesicles by sonication. Biochemistry 18:1702- 1707, 1979.

14.    Chang, B.C. and Huang, L. Synthesis and characterization of a new fluorescent phospholipid. Biochim. Biophys. Acta 556:52- 60, 1979.

15.    Adrian, G. and Huang, L. Entrapment of proteins in phosphatidylcholine vesicles. Biochemistry 18:5610- 5614, 1979.

16.    West, L.K. and Huang, L. Transient permeability changes induced osmotically in membrane vesicles from Torpedo electroplax: a mild procedure for trapping small molecules. Biochemistry 19:4418- 4423, 1980.

17.    Lawman, M.J.P., Naylor, P.T., Huang, L., Courtney, R.J. and Rouse, B.T. Cell mediated immunity to Herpes Simplex virus: induction of cytotoxic T lymphocyte responses by viral antigens incorporated into liposomes. J. Immunol. 126:304- 308, 1980.

18.    Huang, A., Huang, L. and Kennel, S.J. Monoclonal antibody covalently coupled with fatty acid: a reagent for in vitro liposome targeting. J. Biol. Chem. 255:8015- 8018, 1980.

19.    Huang, A., Kennel, S.J. and Huang, L. Immunoliposome labelling: a sensitive and specific method for cell surface labelling. J. Immunol. Meth. 46:141- 151, 1981.

20.    Lee, H.H. and Huang, L. Initiation of developmental biology in the People's Republic of China. J. Tenn. Acad. Sci. 56:110- 111, 1981.

21.    Grant, S.R., Babbitt, B.P., West, L. and Huang, L. A model system for studies of specific membrane interactions. Biochemistry 21:1274- 1279, 1982.

22.    West, L.K. and Huang, L. Acetylcholine receptor- mediated sodium ion efflux after rapid hypo-osmotic loading of radiotracer. Arch. Biochem. Biophys. 215:508- 513, 1982.

23.    Huang, A., Tsao, Y.S., Kennel, S.J. and Huang, L. Characterization of antibody covalently coupled to liposomes. Biochim. Biophys. Acta 716:140- 150, 1982.

24.    Ho, S.C. and Huang, L. Transfer of Torpedo acetylcholine receptors to mouse L- cell surface membranes by liposomes containing Sendai virus envelope proteins. Eur. J. Cell Biol. 27:221- 229, 1982.

25.    Naylor, P.T., Larsen, H.S., Huang, L. and B.T. Rouse. In vivo induction of anti- Herpes Simplex virus immune response by HSV- 1 antigens and lipid A incorporated into liposomes. Infection and Immunity 36:1209- 1216, 1982.

26.    Shen, D.F., Huang, A. and Huang, L. An improved method for covalent attachment of antibody to liposomes. Biochim. Biophys. Acta 689:31- 37, 1982.

27.    Pool, G.L., French, M.E., Edwards, R.A., Huang, L. and Lumb, R.H. Use of radiolabelled hexadecyl cholesteryl ether as a liposome marker. Lipids 17:448- 452, 1982.

28.    Ho, S.C. and Huang, L. A novel cytochemical marker for liposome decomposition in lysosomes. J. Histochem. Cytochem. 31:404- 410, 1983.

29.    Carpenter- Green, S. and Huang, L. Incorporation of acylated wheat germ agglutinin into liposomes. Analyt. Biochem. 135:151- 155, 1983.

30.    Huang, A., Kennel, S.J. and Huang, L. Interactions of immunoliposomes with target cells. J. Biol. Chem. 258:14034- 14040, 1983.

31.    Connor, J., Yatvin, M.B. and Huang, L. pH- sensitive liposomes: acid induced liposome fusion. Proc. Natl. Acad. Sci. U.S.A. 81:1715- 1718, 1984.

32.    Babbitt, B.P., Huang, L. and Freire, E. Thermotropic and dynamic characterization of interactions of acylated alpha- bungarotoxin with phospholipid bilayer membranes. Biochemistry 23:3920- 3926, 1984.

33.    Wang, C.- Y. and Huang, L. Polyhistidine mediates an acid dependent fusion of negatively charged liposomes. Biochemistry 23:4409- 4416, 1984.

34.    Tsao, Y.- S. and Huang, L. Sendai virus- induced leakage of liposomes containing gangliosides. Biochemistry 24:1092- 1098, 1985.
35.    Huang, L. Incorporation of acylated antibody into planar lipid multilayers: characterization and cell binding. Biochemistry 24:29- 34, 1985.

36.    Babbitt, B.P. and Huang, L. Alpha-bungarotoxin attached to and oriented on a lipid bilayer vesicle surface. Biochemistry 24:15- 21, 1985.

37.    Babbitt, B.P. and Huang, L. Effects of valency on thermodynamic parameters of specific membrane interaction. Biochemistry 24:2186- 2194, 1985.

38.    Sullivan, S.M. and Huang, L. Heat- sensitive immunoliposomes: preparation and characterization. Biochim. Biophys. Acta 812:116- 126, 1985.

39.    Connor, J. and Huang, L. Efficient cytoplasmic delivery of a fluorescent dye by pH- sensitive immunoliposomes. J. Cell Biol. 101:582- 589, 1985.

40.    Ho, R.J.- Y. and Huang, L. Interactions of antigen sensitized liposomes with immobilized antibody: a homogeneous solid- phase immunoliposome assay. J. Immunol. 134:4035- 4040, 1985.

41.    Kabalka, G.W., Varma, R.S., Jinaraj, V.K., Huang, L. and Painter, S.K. Synthesis of iodine- 125 labelled w- iodoundecyl cholesteryl ether. J. Labeled Compounds and Radiopharmaceuticals 22:333- 338, 1985.

42.    Norley, S.G., Huang, L. and Rouse, B.T. Targeting of drug loaded immunoliposomes to Herpes Simplex virus infected corneal cells- - an effective means of inhibiting virus replication in vitro. J. Immunol. 136:681- 685, 1986.

43.    Tsao, Y.S. and Huang, L. Kinetic studies of Sendai virus- target membrane interactions: independent analysis of binding and fusion. Biochemistry 25:3971- 3976, 1986.

44.    Connor, J. and Huang, L. pH- sensitive immunoliposomes as an efficient and target- specific carrier for antitumor drugs. Cancer Res. 46:3431- 3435, 1986.

45.    Tsusaki, B.E., Kanda, S. and Huang, L. Stimulation of superoxide release in neutrophils by 1- oleoyl- 2- acetylglycerol incorporated into pH- sensitive liposomes. Biochem. Biophys. Res. Commun. 136:242- 246, 1986.

46.    Ho, R.J.Y., Rouse, B. and Huang, L. Target- sensitive immunoliposomes: preparation and characterization. Biochemistry 25:5500- 5506, 1986.

47.    Wang, C.- Y., Hughes, K. and Huang, L. Improved cytoplasmic delivery to plant protoplasts via pH- sensitive liposomes. Plant Physiol. 82:179- 184, 1986. PMCID: PMC25050

48.    Sullivan, S.M. and Huang, L. Enhanced delivery to target cells by heat sensitive immunoliposomes. Proc. Natl. Acad. Sci. U.S.A. 83:6117- 6121, 1986.

49.    Ho, R.J.Y., Rouse, B.T. and Huang, L. Destabilization of phosphatidylethanolamine immunoliposomes by antigen binding - a valuable approach for rapid virus detection. Biochem. Biophys. Res. Commun. 138:931- 937, 1986.

50.    Connor, J., Norley, N. and Huang, L. Biodistribution of pH- sensitive liposomes. Biochim. Biophys. Acta 884:474- 481, 1986.

51.    Hu, L.R., Ho, R. and Huang, L. Trypsin induced destabilization of liposomes composed of dioleoylphosphatidylethanolamine and glycophorin. Biochem. Biophys. Res. Commun. 141:973- 978, 1986.

52.    Kabalka, G., Buonocore, E., Hubner, K., Moss, T., Norley, N. and Huang, L. Gadolinium- labeled liposomes: targeted MR contrast agents for the liver and spleen. Radiology 163:255- 258, 1987.

53.    Gao, K. and Huang, L. Preparation of colloidal gold labeled agarose- gelatin microspherules for electron microscopic studies of phagocytosis in cultured cells. J. Histochem. Cytochem. 35:163- 173, 1987.

54.    Norley, S., Sendele, D., Huang, L. and Rouse, B. Inhibition of herpes simplex replication in the mouse cornea by drug containing immunoliposomes. Invest. Ophthalmol. Vis. Sci. 28:591- 595, 1987.

55.    Collins, D. and Huang, L. Cytotoxicity of diphtheria toxin A fragment to toxin- resistant murine cells delivered by pH- sensitive immunoliposomes. Cancer Res. 47:735- 739, 1987.

56.    Tsao, Y.- S., Freire, E. and Huang, L. Thermodynamic and phase characterizations of phosphatidylethanolamine and ganglioside GD1a mixtures. Biochim. Biophys. Acta 900:79- 87, 1987.

57.    Gao, K. and Huang, L. Solid core liposomes with encapsulated colloidal gold particles. Biochim. Biophys. Acta 897:377- 383, 1987.

58.    Houck, K.S. and Huang, L. The role of multivalency in antibody mediated liposome targeting. Biochem. Biophys. Res. Commun. 145:1205- 1210, 1987.

59.    Ho, R.J.Y., Rouse, B. and Huang, L. Target- sensitive immunoliposomes as an efficient drug carrier for antiviral activity. J. Biol. Chem. 262:13973- 13978, 1987.

60.    Ho, R.J.Y., Rouse, B. and Huang, L. Interactions of target- sensitive immunoliposomes with herpes simplex virus: the foundation of a sensitive immunoliposome assay for the virus. J. Biol. Chem. 262:13979- 13984, 1987.

61.    Wang, C.- Y. and Huang, L. pH- sensitive immunoliposome mediates a target cell- specific delivery and controlled expression of a foreign gene in mouse. Proc. Natl. Acad. Sci. USA 84:7851- 7855, 1987.

62.    Wang, C.- Y. and Huang, L. Plasmid DNA adsorbed to pH- sensitive liposomes efficiently transforms the target cells. Biochem. Biophys. Res. Commun. 147:980- 985, 1987.

63.    Kanda, S. and Huang, L. Enhanced neutrophil stimulation by phorbol ester encapsulated in pH- sensitive liposomes. J. Liposome Res. 1:63- 79, 1988.

64.    Pinnaduwage, P. and Huang, L. A homogeneous, liposome- based signal amplification for assays involving enzymes. Clin. Chem. 34:268- 272, 1988.

65.    Ho, R.J.Y., Ting- Beall, H.P., Rouse, R. and Huang, L. Kinetic and ultrastructural studies of interactions of target sensitive immunoliposomes with herpes simplex virus. Biochemistry 27:500- 506, 1988.

66.    Pinnaduwage, P. and Huang, L. ß-Galactosidase induced destabilization of liposome composed of phosphatidylethanolamine and ganglioside GM1.    Biochim. Biophys. Acta 939:375- 382, 1988.

67.    Kabalka, G., Buonocore, E., Hubner, K., Davis, M. and Huang, L. Gadolinium- labeled liposomes containing paramagnetic amphipathic agents: targeted MRI contrast agents for the liver. Magnetic Resonance in Medicine 8:89- 95, 1988.

68.    Klibanov, A., Bogdanov, A., Torchilin, V. and Huang, L. Biotin- bearing pH- sensitive liposomes: high- affinity binding to avidin layer. J. Liposome Res. 1:233- 244, 1989.

69.    Liu, D. and Huang, L. Role of cholesterol in the stability of pH- sensitive, large unilamellar liposomes prepared by detergent- dialysis method. Biochim. Biophys. Acta 981:254- 260, 1989.

70.    Liu, D. and Huang, L. Small, but not large, unilamellar liposomes composed of dioloeyl- phosphatidyl-ethanolamine and oleic acid can be stabilized by human plasma. Biochemistry 28:7700- 7707, 1989.

71.    Liu, D., Zhou, F. and Huang. L. Characterization of plasma- stabilized liposomes composed of dioleoylphosphatidylethanolamine and oleic acid. Biochem. Biophys. Res. Commun. 162:326- 333, 1989.

72.    Tari, A. and Huang, L. Structure and function relationship of phosphatidylglycerol in the stabilization of phosphatidylethanolamine bilayer. Biochemistry 28:7708- 7712, 1989.

73.    Pinnaduwage, P., Schmitt, L. and Huang, L. Use of a quaternary ammonium detergent in liposome mediated DNA transfection of mouse L- cells. Biochim. Biophys. Acta 985:33- 37, 1989.

74.    Wang, C.- Y. and Huang, L. Highly efficient DNA delivery mediated by pH- sensitive immunoliposomes. Biochemistry 28:9508- 9514, 1989.

75.    Hughes, B.J., Kennel, S., Lee, R. and Huang, L. Monoclonal antibody targeting of liposomes to mouse lung in vivo. Cancer Res. 49:6214- 6220, 1989.

76.    Pinnaduwage, P. and Huang, L. The role of protein- linked oligosaccharide in the bilayer stabilization activity of glycophorin A for dioleoyl phosphatidylethanolamine liposomes. Biochim. Biophys. Acta 986:106- 114, 1989.

77.    Collins, D., Maxfield, F. and Huang, L. Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway. Biochim. Biophys. Acta 987:47- 55, 1989.

78.    Holmberg, E., Maruyama, K., Litzinger, D.C., Wright, S., Davis, M., Kabalka, G.W., Kennel, S.J. and Huang, L. Highly efficient immunoliposomes prepared with a method which is compatible with various lipid compositions. Biochem. Biophys. Res. Commun. 165:1272- 1278, 1989.

79.    Wright, S.E., White, J.C. and Huang, L. Partitioning of teniposide into membranes and the role of lipid composition. Biochim. Biophys. Acta. 1021:105- 113, 1990.

80.    Liu, D. and Huang, L. pH- Sensitive, plasma- stable liposomes with relatively prolonged residence in circulation. Biochim. Biophys. Acta 1022:348- 354, 1990.

81.    Brynestad, K., Babbitt, B., Huang, L. and Rouse, B.T. Influence of peptide acylation, liposome incorporation, and synthetic immunomodulators on the immunogenicity of a 1- 23 peptide of glycoprotein D of herpes simplex virus: implications for subunit vaccines. J. Virol. 64:680- 685, 1990.

82.    Maruyama, K., Holmberg, E., Kennel, S.J., Klibanov, A., Torchilin, V.P. and Huang, L. Characterization of in vivo immunoliposome targeting to pulmonary endothelium. J. Pharmaceut. Sci. 79:978-984, 1990.

83.    Liu, D., Huang, L., Moore, M.A., Anantharamaiah, G.M. and Segrest, J.P. Interactions of serum proteins with small unilamellar liposomes composed of dioleoylphosphatidylethanolamine and oleic acid: HDL, apolipoprotein A1 and amphipathic peptides stabilize liposomes. Biochemistry 29:3637- 3643, 1990.

84.    Zhu, Z., Hughes, K.W., Huang, L. and Li, X. Cationic liposome- mediated transformation of rice protoplasts. Focus 12:41- 44, 1990.

85.    Zhu, Z., Hughes, K. and Huang, L. Transformation of tobacco protoplasts with DNA entrapped in pH- sensitive liposomes. Plant Cell, Tissue and Organ Culture 22:135- 145, 1990.

86.    Collins, D., Litzinger, D.C. and Huang, L. Structural and functional comparisons of pH- sensitive liposomes composed of phosphatidylethanolamine and three different diacylsuccinylglycerols. Biochim. Biophys. Acta 1025:234- 242, 1990.

87.    Maruyama, K., Kennel, S.J. and Huang, L. Lipid composition is important for highly efficient target binding and retention of immunoliposomes. Proc. Natl. Acad. Sci. USA, 87:5744- 5748, 1990.

88.    Klibanov, A.L., Maruyama, K., Torchilin, V.P. and Huang, L. Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett. 268:235-237, 1990.

89.    Collins, D., Connor, J., Ting- Beall, H.P. and Huang, L. Proton and divalent cations induce synergistic but mechanistically different destabilization of pH- sensitive liposomes composed of phosphatidylethanolamine and oleic acid. Chem. Phys. Lipids 55:339-349, 1990.

90.    Holmberg, E., Maruyama, K., Kennel, S.J., Klibanov, A., Torchilin, V., Ryan, U. and Huang, L. Target-specific binding of immunoliposomes in vivo. J. Liposome Res. 1:393-406, 1990.