Cho Lab of Pharmaceutical Chemistry

Moo J Cho Ph.D.

Associate Professor
Molecular Pharmaceutics

Office
UNC School of Pharmacy
Division of Molecular Pharmaceutics
CB # 7360
Kerr Hall
Chapel Hill, NC 27599-7360

Phone
919-966-1345

Fax
919-966-7778

Email
m_j_cho@unc.edu

 

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References

  • Gratton, S.E.A., Pohlhaus, P.D., Lee, J., Guo, J., Cho, M.J., and DeSimone, J.M. (2007). Nanofabricated Particles for Engineered Drug Therapy: A Prelimnary Biodistribution Study of PRINT Nanoparticles. J. Controlled Release 121:10-18.
  • Palma, E. and Cho, M.J. (2007).  Improved Systemic Pharmacokinetics, Biodistribution, and Antitumor Activity of CpG Oligodeoxynucleotides Complexed to Endogenous Antibodies in Vivo. J. Controlled Release 120:95-103. 
  • Yang, Y., Lee, J., Cho, M.J., and Sheares, V.V. (2006). Synthesis of Amine-Functionalized Diene-Based Polymers as Novel Gene Delivery Vectors. Macromolecules 39:8625-8631.
  • Roberts J., Palma, E., Sazani, P., Ørum, H., Cho, M.J., and Kole, R. (2006). Efficient and Persistent Splice Switching by Systemically Delivered LNA Oligonucleotides in Mice. Molec. Ther. 14: 471-475.
  • Palma, E., Klapper, D. G., and Cho, M. J. (2005). Antibodies as drug carriers III: design of oligonucleotides with enhanced binding affinity for immunoglobulin G. Pharm. Res. 22:122-127.
  • Aravind, A., and Cho, M. J. (2005). Cytosolic Delivery of Macromolecules: 4. Head Group-Dependent Membrane Permeabilization by pH-Sensitive Detergents. J Controlled Release 106:146-153.
  • Asokan, A., and Cho, M. J. (2004). Cytosolic Delivery of Macromolecules. 3. Synthesis and Characterization of Acid-Sensitive Bis-Detergents. Bioconjug. Chem. 15:1166-1173.
  • Chen, F. J., Asokan, A., and Cho, M. J. (2003). Cytosolic Delivery of Macromolecules: I. Synthesis and Characterization of pH-Sensitive Acyloxyalkylimidazoles. Biochim. Biophys. Acta 1611:140-150.
  • Asokan, A., and Cho, M. J. (2003). Cytosolic Delivery of Macromolecules. II. Mechanistic Studies with pH-Sensitive Morpholine Lipids. ibid 1611:151-160.
  • Asokan, A., and Cho, M. J. (2002). Exploitation of Intracellular pH Gadients in the Cellular Delivery of Macromolecules. J. Pharm. Sci. 91:903-913.
  • Rehlaender, B. N., and Cho, M. J. (2001a). Anti-Drug Antibodies as Drug Carriers. I. For Small Molecules. Pharm. Res. 18:745-752.
  • Rehlaender, B. N., and Cho, M. J. (2001b). Antibodies as Drug Carriers. II. For Proteins. Pharm. Res. 18:753-760.