| Center for Integrative Chemical Biology and Drug Discovery |
Stephen
V.
Frye
PhD
Research Professor and Director, Center for Integrative Chemical Biology and Drug Discovery |
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Scientific Advisory Board
Scientific Advisory Board
The CICBDD resources will support progression of 3-5 targets at steady-state with a projected turnover of 2-3 targets per year. Proposals for targets will be reviewed by the scientific advisory board for the Center:
- Alex Tropsha, Medicinal Chemistry
- Bryan Roth, Screening Program Director
- Gary Johnson, Pharmacology
- Matt Redinbo, Chemistry & Biochem
- David Lawrence, Chemistry & Medchem
- Ned Sharpless, Cancer center
- Russ Mumper, Nanotechnology & Drug Delivery
- Howard McLeod, Pharmacogenomics
- Scott Forrest, Tech transfer office
Criteria for evaluation include:
- Disease relevance of target/pathway
- Potential scientific impact of small molecule tools
- Tractability of assay development and ligand discovery
- Portfolio balance and fit with center expertise