DPET Primary Faculty
Kim Brouwer, PharmD, PhD
- William R. Kenan Jr. Distinguished Professor
- Division Chair, Pharmacotherapy and Experimental Therapeutics
Kim L. R. Brouwer's areas of interest include mechanisms of hepatic uptake, translocation and biliary excretion, drug transport, aberrant gastrointestinal drug absorption phenomena, and pharmacokinetics.
Amanda Corbett, PharmD
- Clinical Associate Professor
Amanda Corbett's primary research interests are pharmacology of antiretrovirals and opportunistic infection therapies in resource-poor countries.
Robert Dupuis, PharmD
- Clinical Associate Professor
- Director of Clinical Fellowship Programs, DPET
Bob Dupuis's primary areas of interest include clinical pharmacokinetics/drug metabolism of immunosuppressants in organ transplant recipients and drug interactions with these agents, as well as the relationship between drug metabolism (phenotype and genotype) and toxicity and outcomes.
Roy Hawke, PharmD, PhD
- Clinical Assistant Professor
- Assistant Dean and Director of Graduate Studies
Roy Hawke is interested in the role of drug metabolism enzymes (cytochrome P450s) and hepatobiliary transporters in liver disease pathobiology and drug-induced hepatotoxicity; specifically, in clinical investigations in patients with hepatitis C or NASH (nonalcoholic steatohepatitis), with a focus on the association of disease progression and treatment response with: 1) serum biomarkers of inflammation, apoptosis, fibrosis/cirrhosis and 2) genetic polymorphisms or activity phenotypes for candidate cytochrome P450 and hepatobiliary transporter genes.
Federico Innocenti, MD, PhD
- Associate Professor
- Associate Director for Oncology Research, UNC Institute for Pharmacogenomics and Individualized Therapy
Melanie Joy, PharmD, PhD
- Clinical Associate Professor
- Associate Professor, UNC School of Medicine
Melanie Joy is interested in chronic kidney disease, pharmacokinetic/pharmacodynamic changes of drugs in renal disease and dialysis, alterations in drug transporters and drug metabolizing enzymes in kidney diseases, and kidney diseases resulting from exposure to drugs and their metabolites.
Angela DM Kashuba, PharmD
- Professor
- Director, UNC Center for AIDS Research Clinical Pharmacology and Analytical Chemistry Core
Angela Kashuba's primary interest is clinical pharmacology of antiretroviral agents used in the treatment of HIV infection; specifically, the role of antiretroviral therapy in preventing the transmission of HIV, determining optimal dosing and drug combinations for the treatment of HIV infection, understanding and predicting drug-drug and drug-cytokine interactions and adverse effects, and the role of sex and ethnicity in drug disposition.
Craig Lee, PharmD, PhD
- Assistant Professor
- Director of Graduate Admissions, DPET
Craig Lee is primarily interested in the role of genomics in the development, progression and treatment of cardiovascular disease, with a focus on eicosanoid metabolism and endothelial dysfunction.
Howard McLeod, PharmD
- Fred Eshelman Distinguished Professor
- Director, Institute for Pharmacogenomics and Individualized Therapy
Mary Paine, PhD
- Assistant Professor
Mary Paine's primary areas of interest include clinical pharmacokinetics, drug metabolism and transport, and pharmacogenetics. She is currently investigating pharmacokinetic mechanisms underlying drug-drug and drug-diet interactions.
Herb Patterson, PharmD
- Professor
- Executive Vice Chair, DPET
Herb Patterson is primarily interested in clinical research of drugs used in heart failure.
Adam Persky, PhD
- Clinical Associate Professor
Adam Persky's areas of interest include pharmacy education, pharmacokinetics, pharmacodynamics of dietary supplements, interaction of exercise and/or nutrition on drug disposition and action, skeletal muscle physiology and pathophysiology, as well as agents that influence form and function.
A. Wayne Pittman, MS Pharm
- Associate Professor of Pharmacotherapy
- Clinical Associate Professor of Medicine
Jo Ellen Rodgers, PharmD
- Clinical Associate Professor
- Associate Director, Clinical Fellowship Programs, DPET
Jo Ellen Rodgers is interested in clinical and translational research in heart failure.
Dhiren Thakker, PhD
- Associate Dean for Economic Development and International Partnerships
- Ferguson Distinguished Professor
Dhiren Thakker's primary interests include mechanisms of drug transport, structure-transport relationships, prodrug strategies for tumor-targeting, metabolism of drugs and xenobiotics, as well as delivery and disposition of macromolecule.
Christine Walko, PharmD
- Clinical Assistant Professor
Chris Walko's primary areas of interest include oncology-based research in translational pharmacology, phase I/II trials, pharmacokinetics, and pharmacogenomics.
Paul Watkins
- Professor
- Director, Hamner–UNC Institute for Drug Safety Sciences
Paul Watkins is interested in mechanisms that underlie serious liver injury due to drugs. His research spans preclinical models to patients in clinical trials and utilizes current genomics technologies, including genetics, transcriptomics, and metabolomics.
Dennis Williams, PharmD
- Associate Professor
- Vice Chair for Professional Education and Practice, DPET
Tim Wiltshire, PhD
- Associate Professor
- Associate Director, Institute for Pharmacogenetics and Individualized Therapy
William Zamboni, PharmD, PhD
- Associate Professor
- Director, GLP Analytical Facility
