Institute for Pharmacogenomics and Individualized Therapy

The Institute brings together researchers and clinicians across the University to create personalized therapies and treatments for patients suffering from a wide variety of conditions. IPIT will also offer the services of core facilities in molecular genomics, cellular phenotyping, and bioinformatics to add to the excellent core facilities already existing at UNC.

The UNC Cellular Metabolism
and Transport Core

The Core develops new experimental methodolgies, based on organ perfusion technologies, that can be applied to experimentation typically required for drug development and evaluation. The scope of the Core is to perform experimentation in a variety of isolated or in situ organs and tissues. These experimental techniques and models are available to investigators on a fee-for-service basis in three general areas including cell isolation, drug disposition, and drug action.

Center for AIDS Research Clinical Pharmacology and Analytical Chemistry Laboratory

The purpose of the Clinical Pharmacology and Analytical Chemistry Laboratory (Core E) is to provide a centralized unit to facilitate the pharmacological and analytical studies of HIV/AIDS related clinical, translational, and basic science research at UNC-Chapel Hill and at our collaborating institutions, and to establish collaboration with AIDS investigators at other national and international institutions.

Pharmacometrics Core

The Pharmacometrics Core assists investigators at each step in the pharmacokinetic/pharmacodynamic research process, from study design and data analysis to publication.

ADME Mass Spectrometry Center

The ADME Center focuses on small molecule analysis involving quantitation by triple quadrupole spectrometry, molecular weight determination by ion trap spectrometry, and targeted identification of novel metabolites by UV, fluorescence, and mass spectrometry.  We can provide the training, resources and expertise to produce first-rate, publication quality results for all our clients.

Good Laboratory Practice
Analytical Facility

The GLP Analytical Facility will support the development of newly discovered drugs and medical testing procedures. The lab will have the capacity to support all pharmacologic studies required as part of the translational development of drugs.