Wei Yue, PhD, received her PhD after completing the joint PhD program in the Department of Immunology at the Peking Union Medical College and the Department of Developmental Biology at Shandong University in China. After graduation, she joined the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill for her postdoctoral training. At the LCCC, she focused on studying tumor virology and the posttranslational regulation of virus-host interactions by phosphorylation and ubiquitination. While working in the field of cancer research, Yue became interested in drug transport proteins, particularly in how posttranslational modifications may regulate drug transport protein function and affect transport-mediated drug-drug interactions. Yue joined the Division of Pharmacotherapy and Experimental Therapeutics at the UNC Eshelman School of Pharmacy in 2007 as a postdoc and was appointed as a research assistant professor in 2008.

Currently, Yue directs an NIH-funded research program focused on studying the function and regulation of organic anion transporting polypeptides (OATP) 1B1 and OATP1B3, two hepatic uptake transport proteins, aiming to predict OATP-mediated drug-drug interactions and toxicities.

Research Interests

Dr. Yue's primary areas of interest include investigating the role of OATPs in healthy and disease states, including cancers, and establishing a mechanistic model to predict OATP-mediated drug-drug interactions and toxicities.