Dr. Jin is currently an associate professor and director of medicinal chemistry in the Center for Integrative Chemical Biology and Drug Discovery at the University of North Carolina at Chapel Hill. Prior to joining UNC-Chapel Hill in August 2008, Dr. Jin had more than ten years of medicinal chemistry and drug discovery experience at GlaxoSmithKline, where he most recently served as a manager of medicinal chemistry from 2003 to 2008. Dr. Jin has led numerous multi-disciplinary small molecule drug discovery programs that successfully delivered numerous high quality leads and precandidates that led to multiple clinical candidates during his career at GSK.

Dr. Jin received a BS in chemistry from University of Science and Technology of China in 1991 and a PhD in natural product total synthesis from the Pennsylvania State University in 1997. He then completed a one-year post-doctoral training at the Ohio State University prior to joining GSK.

To date, Dr. Jin has published 62 papers (40 papers since 2008). In addition, he is an inventor of 41 issued patents and patent applications.

Current research interests include discovering

• Chemical probes of protein methyltransferases,
• Nonnucleoside inhibitors of DNA methyltransferases, and
• Functionally selective ligands of GPCRs.

Recent press releases and feature articles

UNC Scientists Create "Excellent" Probe to Study Gene-Controlling Proteins

Jian Jin and molecular probe UNC0638 for G9a & GLP featured in UNC Endeavors October 2011

Discovery by Jin, Roth Could Lead to Better Schizophrenia Drugs (highlighted by SciBX as a cover story)

UNC Spotlight

Lab Website: http://pharmacy.unc.edu/research/labs/jian-jin-lab